An introducer needle may include a proximal end, a distal tip, and a needle lumen extending therebetween. The introducer needle may include a wall defining the needle lumen, a first notch formed through the wall, and a second notch formed through the wall. A catheter system may include a catheter adapter, a catheter extending distally from the distal end of the catheter adapter, a flash chamber coupled to the introducer needle, and the introducer needle, which may extend through the catheter. The first and second notches and the flash chamber may facilitate pressure-driven blood flow into the catheter for improved flashback and detection of transfixation when the catheter is primed prior to insertion into vasculature of a patient or otherwise.

The present disclosure relates to a hemodialysis catheter that can monitor intravascular pressure using a MEMS sensor. The hemodialysis catheter comprises a venous lumen, an atrial lumen, and at least one MEMS system sensor. The hemodialysis catheter also comprises a data acquisition and processing system. The hemodialysis catheter can communicate with a monitor system to display pressure data.

Aspects of systems and methods for controlling SAR in medical infusion illumination are disclosed herein. In one aspect a system for reducing microorganism load in an environment surrounding an electronic illuminator is disclosed. In the system an electronic illuminator is disclosed comprising an LED module, a power driver equipped to the LED module for driving power to the LED, housing to protect the contents of the electronic illuminator and dissipate heat, and a PCB configured with an MCU for controlling operations within the electronic illuminator. Further, the system comprises a side emitting fiber optic line or line, also known as side glow fiber. The side emitting fiber optic line comprises a funnel cap for engaging with the electronic illuminator and a protective end cap for protecting and reflecting light radiation. In other aspects, a method for reducing microorganism count in an environment surrounding an electronic illuminator is disclosed. The method comprises provisioning an electronic illuminator equipped with an LED module and a side emitting fiber optic line. Then transmitting a signal, to a power driver of the LED module to begin the microorganism reduction. Next, emitting light radiation, by the LED module, and lastly terminating the light radiation after a set duration.

A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.

A multi-lumen extension system may include a first lumen forming a fluidic channel within the multi-lumen extension system; a second lumen forming a non-fluidic channel within the multi-lumen extension system; a patency instrument housed within the second lumen; a seal between the first lumen and the second lumen to prevent fluid from entering the second lumen from the first lumen; and a grip formed along the second lumen and operatively coupled to the patency instrument housed within the second lumen to selectively advance the patency instrument along the second lumen.

An introducer needle may include a proximal end, a distal tip, and a needle lumen extending therebetween. The introducer needle may include a wall defining the needle lumen, a first notch formed through the wall, and a second notch formed through the wall. A catheter system may include a catheter adapter, a catheter extending distally from the distal end of the catheter adapter, a flash chamber coupled to the introducer needle, and the introducer needle, which may extend through the catheter. The first and second notches and the flash chamber may facilitate pressure-driven blood flow into the catheter for improved flashback and detection of transfixation when the catheter is primed prior to insertion into vasculature of a patient or otherwise.

A system and method for controlling and monitoring a diabetes-management system through the use of a model that predicts or estimates future dynamic states of glucose and insulin from variables such as insulin delivery or exogenous glucose appearance as well as inherent physiological parameters. The model predictive estimator can be used as an insulin bolus advisor to give an apriori estimate of postprandial glucose for a given insulin delivery profile administered with a known meal to optimize insulin delivery; as a supervisor to monitor the operation of the diabetes-management system; and as a model predictive controller to optimize the automated delivery of insulin into a user's body to achieve a desired blood glucose profile or concentration. Open loop, closed-loop, and semi-closed loop embodiments of the invention utilize a mathematical metabolic model that includes a Minimal Model, a Pump Delivery to Plasma Insulin Model, and a Meal Appearance Rate Model.

An injection needle has an opening at a distal end thereof the injection needle and defines a hole. An optical fiber is configured to output a light from a light source and inserted in the hole. The optical fiber has a distal end positioned on an inner side of the opening. A protector is configured to transmit the light and is positioned further towards an opening side of the injection needle than the distal end. The protector is configured to prevent adherence of tissue to the optical fiber. The light emitted from the optical fiber is configured to irradiated onto a treatment target in a state in which the injection needle is inserted into skin, the distal end is positioned on an inner side of the opening, and the protector is positioned further towards the opening side of the injection needle than the distal end.

An apparatus includes a needle, a cutter, a medication fluid path, and a filter assembly. The needle defines a tissue receiving feature. The cutter is movable relative to the needle to sever tissue protruding into the tissue receiving feature. The medication fluid path includes a first portion and a second portion. The first portion is configured to couple with a source of medication fluid. The tissue receiving feature is in fluid communication with the medication fluid path such that the first portion is upstream of the tissue receiving feature. The filter assembly is located in the second portion of the medication fluid path. The filter assembly is configured to permit air to pass through the filter assembly. The filter assembly is further configured to prevent medication fluid from passing through the filter assembly.

A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.