A garment (e.g., a shirt) for monitoring biometric properties of the wearer of the garment is disclosed. The garment may include sensors for monitoring or assessing the vital signs and body position of the wearer. A processor associated with the garment may provide an output indicative of an assessed condition of the wearer based on the assessed vital signs and the assessed body position of the wearer of the fabric. The garment may include an injector assembly that is used to administer a drug injection to the wearer when the assessed condition indicates that the wearer is in an alert condition.

Tissue access devices and methods of using the same are disclosed. The devices can have a sensor configured to occlude a flow path by deflecting a membrane into the flow path when the devices become dislodged from tissue. The sensor can be configured to partially or fully occlude the flow path. The sensor can have a spring. The spring can be biased to move the sensor from a sensor first configuration to a sensor second configuration when a force applied by the sensor first surface against a non-sensor surface changes from a first force to a second force less than the first force. The membrane can be deflected into the flow path when the sensor is in the sensor second configuration.

Needle insertion mechanisms include a housing and a needle holder, the needle holder being linearly guided by the housing to be moved along the needle-axis. A slider linearly guided by the housing and transversally moveable with respect to the needle-axis from a first to a second slider position. The needle holder is operatively coupled to the slider when the slider is in the first position, thereby retaining the needle holder in a retracted position against the bias of a spring acting on the needle holder. In the second position the slider is decoupled from the needle holder and the holder is moved into an inserted position by the spring. A blocking member arranged between the slider and the housing blocking movement of the slider into the second position, is moved by an active drive thereby unblocking the movement of the slider and subsequently moving the slider to the second position.

A hub member for an infusion set device includes a body and pads configured to receive a squeezing force directed radially inward relative to an axis of the body. The body compresses radially inward relative to the axis in response to the squeezing force. A plurality of connection features on the body are moveable from a first position radially inward toward a second position when the hub member is compressed radially inward. The connection features engage one or more further connection features on a housing to attach the hub member to the housing when the connection features are in the first position, and disengage the further connection features to release the hub member when the connection features are moved toward the second position.

Tissue access devices and methods of using and making the same are disclosed. The devices can have a needle, a housing having wings, a tube having a flow channel, a tube first extension, and a tube second extension, and a torsion spring having a first coil and a second coil. The first coil can have a first coil first arm and a first coil second arm. The first coil first arm can be shorter than the first coil second arm. The second coil can have a second coil first arm and a second coil second arm. The second coil first arm can be shorter than the second coil second arm. The devices can have a sensor. More energy can stored in the torsion spring when the sensor is in a sensor closed configuration than when the sensor is in a sensor open configuration.

The present solution provides trans-round window membrane (RWM) drug delivery. As an overview, the system can include a micropump that is connected to a flexible cannula. The cannula can include a stiffened and sharpened tip to facilitate insertion through the RWM. The cannula can be inserted through the RWM to improve the distribution of the delivered drug throughout the inner ear. The present solution can function as a small implantable or wearable device that can be used for both chronic and acute trans-RWM drug delivery. With this configuration, the micropump can constantly or intermittently deliver, over a period of days to months, small volumes of drugs from an internal reservoir.

The cover for a drug delivery tube device according to a disclosed embodiment is configured to define an insertion space having an opening formed on a lower side thereof so that the drug delivery tube device having a capillary flow path configured to allow a drug solution to flow therethrough is capable of being inserted into the opening. The cover includes a cover body extending along a circumference of the insertion space around a center axis perpendicular to an upper-lower direction.

Devices, systems, and methods are provided herein for delivering medication (e.g., insulin) via a wearable pump having a patch-style form factor for adhesion to a user's body. The reusable pump may be coupled to a disposable cap housing a microdosing system for delivering precise, repeatable doses of medication to a cannula configured to deliver medication to a target infusion area beneath the user's outer skin layer. The system further may include an applicator for inserting the cannula into the user's skin and/or applying an adhesive pad to the skin.

Devices, systems, and methods are provided herein for delivering medication (e.g., insulin) via a wearable pump having a patch-style form factor for adhesion to a user's body. The reusable pump may be coupled to a disposable cap housing a microdosing system for delivering precise, repeatable doses of medication to a cannula configured to deliver medication to a target infusion area beneath the user's outer skin layer. The system further may include an applicator for inserting the cannula into the user's skin and/or applying an adhesive pad to the skin.