An indwelling assembly includes an inner needle having a sharp needlepoint, an inner needle hub fixed to the inner needle, a hollow elongated outer member in which the inner needle is positioned and movable in a distal direction relative to the inner needle after puncturing the blood vessel to position the elongated outer member at a desired position in the blood vessel, an outer member hub fixed to hollow elongated outer member, a projection removably connected to the outer member hub and configured to be engaged by a finger of the user to apply a force to the projection causing the outer member hub and the hollow elongated outer member to move together with the projection in the distal direction relative to the inner needle and the inner needle hub, and an elongated movable member that is movable relative to the hollow elongated outer member and the outer member hub.

In an aspect, the present disclosure provides a combined drug delivery cannula and continuous glucose sensor that measures glucose without interference from the drug excipient, said cannula being a hollow tube, the outer wall of which includes: an electrode layer with at least one indicating electrode, said layer underlying a redox-catalytic layer that includes an osmium compound bound to a ligand, and either glucose oxidase or glucose dehydrogenase.

Embodiments relate to subcutaneous insertion systems comprising a surface device to be applied to a patient's skin and an insertion system for applying the surface device to the patient, wherein the applying can include subcutaneous insertion of a cannula or other element, and related devices and methods. The surface device comprises a surface for application to the skin of a patient and a subcutaneous element, such as a cannula, wire, filament or other device, extending from the skin's surface at an angle greater than 0 degrees and less than 90 degrees.

A delivery device is provided for introducing a fluid to a patient. The delivery device has a base with a bottom face for attaching to the skin of the patient, and a cannula extending from the bottom face for penetrating the skin of the patient. A fluid supply conduit has a first lumen connected to the cannula for supplying the fluid to the cannula, where the fluid contains an active agent and stabilizing agent. The conduit has a second lumen with an open end for capturing leakage of the fluid from the infusion site and carrying the fluid away from the infusion site. The second lumen has a leak detector containing a color changing in an amount to react with the stabilizing agent and produce a visual indication to the patient through the conduit. The leak detector is spaced from the infusion site and oriented in a location visible by the patient through the conduit.

A catheter system may include a catheter assembly, a fluid storage unit, and fluid. The catheter assembly may include a catheter hub, a catheter, an extension tube, and an adapter. The catheter hub may include a distal end, a proximal end, a lumen extending between the distal end and the proximal end, and a side port. The catheter may extend distally from the distal end of the catheter hub. A distal end of the extension tube may be coupled to the side port. The adapter may be coupled to a proximal end of the extension tube. The fluid storage unit may be coupled to the adapter and may include a reservoir, a barrier, and an actuator. The fluid may be disposed within the reservoir. In response to breach of the barrier by the actuator, the reservoir may be in fluid communication with the lumen of the catheter hub.

A drug infusion set is provided, in which a catheter fixing unit and a drug infusion unit are mounted/unmounted, the catheter fixing unit includes a body member, which includes a guide unit, in which a receiving space is formed in a downward direction from an upper surface; a drug injection unit, in which an accommodation space is formed in a horizontal direction from the other side to communicate with the guide unit, and into which the drug infusion unit is inserted; and a catheter insertion unit, which extends in a downward direction of the guide unit; a guided insertion member, which is provided with a guide needle, inserted into the guide unit; first and second sealing members, which are inserted into the accommodation space of the guide unit and the drug injection unit; and a catheter, which is inserted into the catheter insertion unit.

The present invention relates to a needle having safety mechanism and particularly relates to a huber needle assembly (10; 110) having safety mechanism comprising a needle hub (12; 112), a base (14; 114), a huber needle (16; 116) slidably disposed through the needle hub (12; 112), a wing holder (16; 116) having two wings (18; 118) at the opposite end of the wing holder (16; 116), a connector (24; 124) which connect the needle hub (12; 112) and the base (14; 114) for protecting the tip of the huber needle.

A portable electronic fluid dispensing system can provide pre-filled, pre-primed IV bag assemblies comprising therapeutic fluids. The same fluid line and connector in the IV bag assembly can be used to fill the IV bag as is used to withdraw fluid from the IV bag and infuse such fluid into the patient. The connection points along the IV assembly, such as the connection between the IV bag and a drip chamber, or between an IV bag and tubing, or between a drip chamber and tubing, or between tubing and a closeable, resealable connector, can each be resistant to disconnection by a user. The healthcare practitioner at the patient care site is not required to attach any of these components to each other, and the healthcare practitioner at the patient care site is not required to introduce a spike into a spike port on the IV bag.

This disclosure teaches the concept, and method of creating, a dual use device intended for persons who take insulin. In one embodiment, the novel device is an insulin delivery cannula, the outer wall of which contains electrodes, chemical compounds and electrical interconnects that allow continuous glucose sensing and delivery of data to a remote device. Heretofore, the main problem in attempting to sense glucose at the site of insulin delivery has been the high current resulting from oxidation by the sensor of the preservatives in the insulin formulations. One means of eliminating these interferences is to poise the indicating electrode(s) of the sensor at a bias sufficiently low to avoid the signal from oxidation of the preservatives. One way of obtaining a glucose signal at a low bias is to use an osmium-ligand-polymer complex instead of conventional hydrogen peroxide sensing. Another is to use a size exclusion filter located in line with the insulin delivery tubing in order to remove the smaller phenolic preservative molecules while allowing the larger insulin molecules to pass unimpeded. These filtration concepts can also be more broadly applied, that is, the general concept of removal of unwanted drug formulation excipients from a drug delivery system.

The application relates to an infusion part comprising a cannula part (7) and a fluid path, whereby a sealing (18) is positioned between the cannula part and the inlet/outlet opening (12) of the fluid path when the cannula part is in position for use in order to keep the fluid path to the cannula tight. The sealing (18) is surrounding the inlet/outlet opening (12) and/or the distance di between a centre line c of the cannula part and a point on the outer surface of the cannula part positioned at or above the upper edge of the sealing (18) is larger than the distance 02 between the centre line c of the cannula part and a point on the outer surface of the cannula part positioned at or below the lower edge of the sealing.