A vacuum liquid-filling needle includes a needle shaft (2) and a pressure relief valve (3). The pressure relief valve is disposed within the needle shaft at a first end (21) thereof, and the needle shaft is able to connect at a second end (22) thereof to a pipe for supplying a solution to be filled. The pressure relief valve defines an internal cavity, in which a first slide valve and a second slide valve are disposed so as to be axially spaced apart from each other and both movable relative to the internal cavity. The valve body defines an inflow channel (33), an inflow port (34), an outflow port (35), an outflow channel (37) and exit apertures (38). Each of the inflow channel and the outflow channel is formed by a blind bore, and both the inflow channel and the outflow channel axially extend along the valve body. This vacuum liquid-filling needle can prevent undesired accidental efflux of the solution while providing depressurization and pressure stabilization effects during filling of the solution. Moreover, the solution can be sucked back in a quantitative manner, thus avoiding it from stringing at a dispensing port of the vacuum liquid-filling needle. This makes the filling process more stable, more controllable and suitable for use in precise filling in environments at high vacuum levels. Also disclosed is a pressure relief valve.

An intravenous IV pressure assembly includes a body, an outlet port disposed on the body and a connector coupled to the outlet port, the connector being configured to couple with a fluid reservoir and the IV pressure assembly configured as a pressurized container. IV sets with an IV pressure assembly and methods of operating an IV pressure assembly are also provided.

A method of dispensing a therapeutic fluid from a line includes providing an inlet line connectable to an upstream fluid source. The inlet line is in downstream fluid communication with a pumping chamber. The pumping chamber has a pump outlet. The method also includes actuating a force application assembly so as to restrict retrograde flow of fluid through the inlet while pressurizing the pumping chamber to urge flow through the pump outlet. A corresponding system employs the method.

A catheter for use in medical applications is disclosed. The catheter comprises tubing with a tip hole at one end and an end portion at the other end. Fluid exits the catheter at the tip hole thereof. One or more alternative fluid pathway(s) are provided on the sidewall of the catheter to permit outflow of fluid medication from the catheter to ensure proper delivery of the medication to the intended target area, particularly when the tip opening is occluded or restricted for any reason.

Embodiments described herein generally relate to devices, systems and methods for measuring a volume or number of doses remaining in a drug delivery device that is used for delivering a dose to a patient. In some embodiments, a dose measurement system for measuring the liquid volume in a container includes a light guide disposed and configured to reflect electromagnetic radiation toward the container. The dose measurement system also includes a light guide disposed and configured to emit electromagnetic radiation into the light guide. A plurality of sensors are located in the apparatus that are optically coupleable to the light guide and are disposed and configured to detect the electromagnetic radiation emitted by at least a portion of the light guide. The apparatus also includes a processing unit configured to receive data representing the portion of the detected electromagnetic radiation from each of the plurality of sensors. The processing unit is further operable to convert the received data into a signature representative of the electromagnetic radiation detected by the plurality of sensors.

Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device capable of delivering fluid to a patient involves obtaining, by a control system associated with the infusion device, an input meal indication, obtaining historical data for the patient associated with the input meal indication, determining an estimated carbohydrate amount corresponding to the input meal indication based at least in part on the historical data, determining a bolus dosage of the insulin based at least in part on the estimated carbohydrate amount, and operating an actuation arrangement of the infusion device to deliver the bolus dosage of the insulin to the patient.

A flush device including: a first housing provided with a first flow path; a second housing provided with a second flow path, the second housing being coupled to the first housing; a flow control device including a protrusion and a through hole connecting the first flow path to the second flow path in fluid communication; and an elastic member provided around the base of the flow control device to seal off a space between the first and the second flow paths. The elastic member is deformed to further connect the first and second flow paths in fluid communication. The first housing has an inner periphery provided with fitting receiving portions each being fitted to each of the fitting projections of the protrusion. According to this structure, the flush device can discharge a chemical liquid at a flow rate close to a defined amount.

A fluid delivery system is disclosed which comprises at least one supply station for supplying at least one fluid, a pressurizing unit for pressurizing said at least one fluid, an inlet fluid circuit in fluid communication with said at least one supply station and with a pump module of said pressurizing unit and an outlet fluid circuit in fluid communication with said pump module for discharging the fluid from the chamber. The chamber is provided with a piston reciprocating therein, thereby defining first and second variable-volume sub-chambers. The fluid delivery system further comprises a recirculation fluid circuit fluidically connecting said first and second variable-volume sub-chambers, and an actuator associated to said recirculation fluid circuit for managing the passage of said at least one fluid between said first and second variable-volume sub-chambers in both directions. A method of operating the fluid delivery system is also disclosed.

Systems and methods for drug delivery with pressure sensitive control are disclosed. A drug delivery system may include a reservoir filled or fillable with a drug, a drug delivery device coupled to the reservoir to deliver the drug from the reservoir to a patient, a pressure sensor, an output device, and a controller. The controller may be configured to determine if the drug delivery device has completed delivering a dose of the drug to the patient, and if delivery of the dose of the drug is complete, to measure tissue back pressure using the pressure sensor. Subsequently, the controller may be configured to determine if the tissue back pressure is below a first predetermined value, and if so, control the output device at least once and/or control a mechanism to retract an administration member from the patient.

A method of operating an infusion pump includes transmitting light through or around a drop of fluid suspended from an end of a drip tube for the infusion pump, the end of the drip tube located in a drip chamber for the infusion pump, wherein the drip tube is configured for connection to a source of the fluid; receiving, using an optical system for the pump, light transmitted through or around the drop; transmitting, to a specially programmed microprocessor and using the optical system, data regarding the received light; and, using the microprocessor to calculate a volume of the drop using the data.