An injection system is described that receives, from one or more sensors, a first group of one or more signals indicating a current volume of injection fluid dispensed from a fluid reservoir at a first time. The injection system determines, based on the first group of one or more signals, that a difference between a dispensed volume limit and the current volume of the injection fluid dispensed from the fluid reservoir at the first time is less than a necessary volume of fluid required to complete both a systolic injection phase and a diastolic injection phase. The injection system further, responsive to determining that the difference is less than the necessary volume of fluid required to complete both the systolic injection phase and the diastolic injection phase, controls the injection system to refrain from performing each of the systolic injection phase and the diastolic injection phase.

An intravenous delivery system may operate by gravity feed, and may have a liquid source containing a liquid, a drip unit that receives the liquid from the liquid source, and tubing that receives the liquid from the drip unit for delivery to a patient. A flow rate sensor may be used to measure a flow rate of liquid through the intravenous delivery system, and may generate a flow rate signal indicative of the flow rate. A controller may receive the signal, and may compare the flow rate with a desired flow rate. If the flow rate is more or less than the desired flow rate, the controller may transmit a control signal to a flow rate regulator. The flow rate regulator may receive the control signal and, in response, modify the flow rate to bring the flow rate closer to the desired flow rate.

Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device capable of delivering fluid to a patient involves obtaining, by a control system associated with the infusion device, an input meal indication, obtaining historical data for the patient associated with the input meal indication, determining an estimated carbohydrate amount corresponding to the input meal indication based at least in part on the historical data, determining a bolus dosage of the insulin based at least in part on the estimated carbohydrate amount, and operating an actuation arrangement of the infusion device to deliver the bolus dosage of the insulin to the patient.

The present invention provides a negative pressure guided bone cement injection system comprising a negative pressure system, comprising a negative pressure introduction device, a pushing system for implant bone cement to the target area, a control system for regulating the negative pressure system and the pushing system, and at least one sensing device disposed at any position of the negative pressure system, which can sense at least one environmental parameter for observing the physiological condition of a patient's spinal vertebral body can be monitored immediately, and the result is actively or passively sent back to the system or the operator for adjusting the injection parameters.

A medicinal liquid supply control apparatus according to an embodiment of the present disclosure includes a reservoir located on a second channel to define an internal space that stores a medicinal liquid, an inlet hole and an outlet hole being formed in one portion of an outer surface of the reservoir and connected to the internal space, and a reservoir support part on which the one portion of the reservoir is fixed, an inlet connection hole connected to the inlet hole and an outlet connection hole connected to the outlet hole being formed at the reservoir support part.

A drug delivery system for delivering a drug product is provided that includes a drug product container containing a drug product, a fluid path adapted to receive the drug product from the drug product container, and a drug delivery device positioned along and/or adjacent to the fluid path. The drug delivery device may include a housing, a fluid displacement assembly at least partially supported by and/or surrounded by the housing, and a drive component at least partially supported by and/or surrounded by the housing. The drive component may drive the medicament through the fluid displacement assembly. Further, the drug delivery device includes a controller workingly coupled with the drive component for controlling the drug delivery device. The controller may operate in a normal operation mode and a reserve mode.

A system for delivering a medicinal fluid to a patient includes a variable volume pressure delivery chamber, a variable volume medication chamber, an optional medication reservoir, a movable delivery element, a fixed reference volume chamber, a pressure source, and a control sub-system. The variable volume pressure delivery chamber is configured to store pressure controllably. The variable volume medication chamber is fluidically isolated from the pressure delivery chamber and is configured to store medicinal fluid. The movable delivery element is disposed between the medication chamber and the pressure delivery chamber. The pressure source is coupled to the pressure delivery chamber. The control system is configured to selectively cause the pressure source to deliver pressure to the pressure delivery chamber causing the movable delivery element to apply pressure to the medicinal fluid in the medication chamber thereby causing the medicinal fluid to exit the medication chamber at an outlet along the fluid communication path to the patient.

An automatic injection device with flow regulation. The automatic injection device has an insertion needle configured to be inserted into a patient and a drug container which contains a pharmaceutical product and includes a plunger. The automatic injection device also has a fluid path which fluidly connects the drug container to the patient via an insertion needle, a potential energy source, and a regulator configured to restrict release of potential energy and restrict linear movement of the plunger and the pharmaceutical product into the fluid path at a proscribed pace. The regulator includes a clock escapement mechanism and a wire and pulley system including a wire coupled to at least one pulley. The potential energy source may be a spring that surrounds the drug container and may be directly coupled to the plunger and the wire such that movement of the spring and the wire is restricted over time.

Disclosed herein a real time multipurpose infusion monitoring and controlling unit comprising power source, monitor, micro controller and drop rate sensors, wherein said unit is performing employing horizontal screw mechanism adapted to monitor and control the drip by locking the airdrop in the saline tube to make the drip mechanism more accurately and efficiently.

A drive system for a drug delivery device is described. The drive system comprises an axial drive component configured to drive advancement of a stopper sealing a container; a variable rate drive drives advancement of the axial drive component and a controller controls the variable rate drive to deliver a first volume of medicament at a first rate, and a second volume of medicament at a second rate. The controller is configured to: optionally, identify a start point for delivery of medicament from the container, the start point being identified as completion of a predefined preparatory event; drive the variable rate drive at a first speed during a first phase from the identified start point to deliver the first volume of medicament at the first rate; drive the variable rate drive at a second speed during a second phase to deliver the second volume of medicament at the second rate.