Systems and methods for monitoring an operational state and/or a fill status of a drug container of a drug delivery device are provided. The drug container can hold a liquid drug. A plunger can be positioned within the drug container. A drive system can advance the plunger to expel the liquid drug from the container. A monitoring system can detect a movement and/or a position of the plunger and/or any component coupled to the plunger. The detection can enable determination of an amount of liquid drug that has been expelled and/or an amount of liquid drug remaining in the drug container. Dosing rates, flow rates, and dosage completion can also be determined.

A system for delivery of a volume of infusible fluid. The system includes a controller configured to calculate a trajectory for delivering infusible fluid, the trajectory comprising at least one volume of fluid, and determine a schedule for delivering the at least one volume of fluid according to the trajectory, wherein the schedule comprising an interval and a volume of infusible fluid for delivery. The system also includes a volume sensor assembly for determining the at least one volume of fluid delivered, wherein the controller recalculates the trajectory based on the volume of fluid delivered.

A fluid injector system for delivering a multi-phase fluid injection to a patient and methods of fluid delivery is disclosed. Methods of creating and using a multi-aspect fluid path impedance model of the injector system are used. Modeling and adjustment of factors that affect impedance and prevent or reduce backflow, reduce the likelihood of fluid flow rate spikes and provide more accurate flow rates and mixing ratios of fluids may be repeated or happen essentially continuously during an injection. The adjustments may be determined before the injection or determined and/or adjusted during the injection. The determination may include sensor feedback commonly used in injectors such as pressure and position feedback as well as other sensors. In all cases, the user can be notified of adjustments through on-screen notices and/or through the recordation of the injection data by a control device of the injector at the conclusion of the injection.

A data processing device is provided for an anesthesia device for feeding an intravenously administered hypnotic, a volatile hypnotic, and an opioid such that the volume flow can be adjusted. The device determines and standardizes the effective concentrations of the anesthetics. A pharmacokinetic model adds up the standardized concentrations of the hypnotics to a total hypnotic concentration. An isobole is calculated based on a coordinate plane with a total hypnotic concentration axis and an opioid concentration axis, as a function of the currently determined concentrations. The system displays a two-dimensional action diagram with the y-axis as an indicator of the total hypnotic concentration and the x-axis as an indicator of the standardized opioid concentration. The calculated standardized total hypnotic concentration and opioid concentration and the isoboles determined are displayed. The display is adapted to changes occurring in the isoboles determined in the course of time.

Systems and methods for controlling fluid delivery via a manually administrable medication container to a patient through a fluid delivery pathway are provided. The systems and methods described herein incorporate rules-based clinical decision support logic to drive a flow control valve within a flow pathway based on a determination of whether or not an IV fluid connected to an input port on the pathway is appropriate for patient administration by considering such factors as patient-specific clinical circumstances, current medical orders, and accepted delivery protocols. Related apparatus, systems, methods and articles are also described.

A flow meter includes an image sensor and a processor. The image sensor is configured to capture an image of a drip chamber. The processor is configured to determine whether the captured image of the drip chamber contains a match to a template, and to apply a blurring function to the image captured by the image sensor of the drip chamber such that the processor can determine if the captured image contains a match to the template.

A flow meter includes a first image sensor, a background pattern, and at least one processor. The first image sensor has a first field of view and is positioned to view a drip chamber within the first field of view. The background pattern is positioned within the field of view of the first image sensor, and the background pattern includes first and second portions. The processor is operatively coupled to the first image sensor and configured to: receive a first image from the first image sensor, and estimate at least one parameter of liquid within the drip chamber in accordance with a distortion of the background pattern caused by the liquid as indicated by the first image.

A filling aid. The filling aid includes a needle housing portion including at least one tab having a starting position and a filling position, and a filling needle cradle including a filling needle, the filling needle cradle slidable connected to the needle housing portion and having a starting position and a filling position, wherein when the at least one tab on the needle housing moves from a starting position to a filling position, the filling needle cradle slides from a starting position to a filling position, and wherein when the at least one tab on the needle housing moves from a filling position to a starting position, the filling needle cradle slides from a filling position to a starting position.

A system for delivery of a volume of infusible fluid. The system includes a controller configured to calculate a trajectory for delivering infusible fluid, the trajectory comprising at least one volume of fluid, and determine a schedule for delivering the at least one volume of fluid according to the trajectory, wherein the schedule comprising an interval and a volume of infusible fluid for delivery. The system also includes a volume sensor assembly for determining the at least one volume of fluid delivered, wherein the controller recalculates the trajectory based on the volume of fluid delivered.

A flow metering insert (10) for a drip chamber (50) is provided that is suitable for use in intravenous administration. The insert comprises: a primary liquid flow channel with an inlet, an outlet, and a flow-resistant passage between the inlet and the outlet; and a flow indicating channel in communication with the primary liquid flow channel between the inlet and the flow-resistant passage. The flow-resistant passage provides a resistance to liquid flow such that liquid is forced into the flow indicating channel and reaches a height proportional to the rate of liquid flow through the primary liquid flow channel. The flow-resistant passage and the flow indicating channel are at least partially defined by one or more first recesses and/or channels in the insert such that the flow-resistant passage and the flow indicating channel are formed between the insert and a wall of the drip chamber when the insert is inserted into the drip chamber.