An exemplary embodiment of an injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger mechanism can include a floating trigger member having a retaining portion, a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly further having a floating trigger engagement member configured to engage the retaining portion of the floating trigger member when the floating trigger member is in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation of the floating trigger member from the pre-firing condition to a firing condition in which the floating trigger engagement member is released from the retaining portion to allow the energy source to fire the ram.

A medicament delivery device includes a generally elongated tubular housing having opposite proximal and distal parts; a needle shield sleeve slidably and coaxially arranged inside the housing with a proximal part of the sleeve protruding a distance outside the proximal part of the housing; a syringe carrier mechanism having a syringe carrier slidably and coaxially arranged within the needle shield sleeve, a syringe having a stopper, a medicament, and a needle, the syringe being coaxially arranged within the syringe carrier; and a holding member connected to the syringe carrier; a first activator member an a second activator member; a drive mechanism adapted to accumulate a drive force for moving the syringe carrier mechanism in a first step and a second step. The second activator member is arranged within an information device for producing audible, visual, and/or tactile feedback to a user about a completed injection.

A power pack for use with a medicament delivery device is presented having a plunger rod movable along a longitudinal axis; a drive spring operably connected to said plunger rod; a plunger rod sleeve arranged with holding elements for releasably holding said plunger rod with said drive spring in a tensioned state. Signal initiating elements are arranged to said plunger rod; and signal generating elements arranged to cooperate with said signal initiating elements for providing information to a user of a medicament delivery device about the movement of said plunger rod when said plunger rod sleeve has been activated to release said holding elements.

A device, method, and system are provided for treating pleural effusion by administration of a chemical agent through a pleural catheter to achieve pleurodesis. A first embodiment includes a dual barreled syringe to deliver the sclerosing agent; one barrel includes a sclerosing agent, and the other barrel includes a flushing fluid. A kit of the invention comprises a plurality of syringe devices each preloaded with a sclerosing agent matched with a presumptive diagnosis regarding the etiology of the pleural effusion to be treated. A device of the invention includes a handheld, disposable, electronic delivery device with preloaded chambers holding selected medicaments and flushing fluid. Automatic delivery of medicaments is achieved in which a microcontroller of the device controls evacuation of the selected chambers by one or more actuators that communicate with the chambers.

The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament and to an insert for such a device. The insert comprises a cup-shaped body with a distal end and a proximal end. The body has a sidewall and a tube which extends centrally through the cup-shaped body in a longitudinal direction, thereby defining an annular space between the sidewall and the tube. The annular space is open in the proximal direction for receiving a compression spring. The tube comprises a thread provided at an inner surface of the tube. Further, the tube, the sidewall and/or a second part comprise a clutch feature for rotationally constraining a component part to the insert.

The present disclosure concerns an indication mechanism for an automatic applicator, particularly for insulin or other liquid preparations, particularly for multiple injection administration of set doses of a medicine from an exchangeable container, for example for the self-application of insulin by diabetes patients. An indication mechanism for an automatic applicator, having an assembly of at least two barrels movably coupled to each other has an indication barrel mounted on the driving barrel contains only marking on its external surface and is co-axially connected to the pull-push control nut.

A system for injecting medium into a patient includes an automated injector including a reservoir, an ejector for ejecting a volume of fluid medium from the reservoir, and an actuator coupled to the ejector. An input device includes a syringe housing, a plunger, a circuit board coupled to a first component of the input device, a plunger position sensor, a battery, and a transmitter for sending an input device action signal to the automated injector. The input device action signal is based at least in part on a signal sent from plunger position sensor. A diversion apparatus is disposed downstream from the reservoir and is configured to receive at least a first portion of the volume of the fluid medium ejected from the reservoir.

A method for assembling a drive spring, especially into a drug delivery device includes rotating a component part to which the drive spring is attached in a first direction, followed by a rotation of the component part in the opposite direction and followed by attachment of a rotational stop. Further, the disclosure includes a drug delivery device for selecting and dispensing a number of user variable doses of a medicament, which device comprises a pre-charged drive spring.

An autoinjector is described that includes an outer body, a first trigger, an output needle, and a first compartment. The first compartment is positioned within the outer body and includes (i) a main body, (ii) a first biasing member coupled to the first trigger, and (iii) a protrusion positioned at a distal end of the main body. The autoinjector further includes a second compartment positioned in the outer body and in fluid communication with the first compartment and the output needle. The autoinjector also includes a second biasing member coupled to a second trigger. The first biasing member is configured to, upon application of force to the first trigger, automatically move an ampule in a distal direction relative to the main body to force the ampule against the protrusion, so as to break the ampule and allow a medicament to flow from the ampule to the second compartment.

An infusion device includes a housing with an interior chamber sized and configured to hold at least a flange and plunger of a syringe, a trigger held by the housing, and a lever in communication with the trigger and including an upwardly extending cam with a cam path having an upper end. The cam is in communication with the flange of the syringe. In response to actuation of the trigger to dispense fluid from the syringe, the upper end of the cam travels upward above the syringe and longitudinally toward a dispensing end of the syringe to linearly translate the plunger of the syringe in a first direction to dispense fluid from the syringe. To refill fluid into the syringe, the upper end of the cam travels downward and longitudinally away from the dispensing end of the syringe to linearly translate the plunger in a second direction to intake fluid.