An auto-injector for administering a dose of a liquid medicament (M) is presented having an elongate case, a carrier subassembly comprising a tubular carrier slidably arranged inside the case, where the carrier adapted to contain a syringe with a hollow injection needle. The injector also has, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for advancing the needle beyond a proximal end of the auto-injector, and a trigger button is used for releasing the control spring on actuation.

A system determines the location of a tip of a hypodermic needle by moving a needle along a path, shining light from two sources onto respective portions of the path, and analysing signals received from the respective light sources that have been reflected by the needle.

An automatic injector dispenses a predetermined dose of medicament without a user having to manually force the needle into an injection site. The automatic injector includes a needle cover having a locked retracted position with respect to the injector housing prior to a medicament dispensing operation. The needle cover is operative to engage an injection site prior to a medicament dispensing operation.

An apparatus (100) for use with an auto-injector configured to receive a syringe and comprising: a firing assembly (102) comprising a rearward portion (108), a plunger rod (110) moveable forward relative to the rearward portion (108) and a plunger rod driver (112) configured to drive the plunger rod (110) forward relative to the rearward portion (108); an insertion driver (106) configured to drive the syringe forwards on an insertion stroke for inserting a needle of the syringe into an injection site; and wherein the firing assembly (102) further comprises a retainer (114) engaged with the plunger rod (110) and/or the rearward portion (108) and configured to prevent forward movement of the plunger rod (110) relative to the rearward portion (108), and to disengage from the firing assembly (102) at a point on the insertion stroke.

Devices and methods are provided for delivering gas. In one example, the device includes a syringe body including a proximal end, a distal end including an outlet and a gas chamber communicating with the outlet, and a plunger carrying a piston slidably received within the syringe body. A canister containing a gas is provided within the plunger adjacent a passage through the piston communicating with the gas chamber. A drive actuator is movable to cause an opener pin to open a septum of the canister and release the gas, whereupon the gas travels through the passage into the gas chamber, thereby displacing the piston proximally to fill the gas chamber. Once activated, the plunger may be advanced to deliver the gas within the gas chamber through the outlet into a patient's body, e.g., into an eye via a cannula connected to the outlet.

The present disclosure relates to a medicament delivery device. The medicament delivery device comprises a housing, a needle and a reservoir. The needle is configured to project from a distal end of the housing. The reservoir is disposed in the housing and has a flexible wall. The medicament delivery device further comprises a dispensing member and a biasing member. The dispensing member is disposed in the housing and the biasing member is configured to bias the dispensing member to move in an arcuate path relative to the housing such that the dispensing member moves across the flexible wall of the reservoir to dispense medicament from the reservoir when the reservoir contains medicament.

A medicament delivery device is presented having a medicament container having an attached medicament delivery member; a housing where the medicament container is movable between a retracted and an extended position in which the medicament delivery member extends from the housing; a drive unit that advances the medicament container from its retracted position to its extended position to expel the contents through the medicament delivery member; and a medicament container holder for carrying the medicament container as it is advanced, the medicament container holder having a proximal end through which the medicament delivery member extends and a holding member releasably connected to the drive unit and attached to the medicament container holder. The holding member has a biasing element having a resilient structure in the form of a tubular wall provided with slots extending in the generally circumferential direction arranged to bias the medicament container in the proximal direction in the medicament container holder.

An autoinjector includes a case adapted to hold a medicament container having a needle, a needle shroud telescopically coupled to the case, and a plunger rotationally and slidably disposed in the case. The needle shroud is movable between a first extended position relative to the case in which the needle is covered and a retracted position relative to the case in which the needle is exposed. The plunger is rotatable relative to the case between a first rotational position in which the plunger is engaged to the case and a second rotational position in which the plunger disengages the case. The needle shroud is operably coupled to the plunger. When the needle shroud translates from the first extended position to the retracted position, the plunger rotates from the first rotational position to the second rotational position.

Impact testing apparatuses are disclosed which simulate and measure various impact-related events associated with the operation of a drug delivery device. The impact testing apparatus may include an impactor configured to simulate a plunger rod of the drug delivery device, and a guide sleeve configured to receive a syringe corresponding to the drug delivery device. The syringe may have a proximal end, a distal end defining an outlet, and an interior chamber extending between the proximal and distal ends and carrying a plunger. Additionally, the impact testing apparatus may include an energy source configured to reduce a distance between the impactor and the plunger so that the impactor strikes the plunger. Various sensors may be included to measure characteristics of one or more impacts caused by the impactor. Methods of impact testing a syringe filled with a fluid and carrying a plunger are also disclosed.

Systems and methods for automatic intravenous injection in accordance with embodiments of the invention are illustrated. One embodiment includes a method for automatically injecting a needle into a vein. The method includes steps for identifying an injection position using a first set of one or more sensors, positioning an injection mechanism at the identified injection position, and vertically inserting a needle until entry in a vein is detected using a second set of one or more sensors.