A disposable transfer device has an injection device support surface for receiving an on-body injection device thereon and a flow path arrangement for transfer of fluid into the injection device, the transfer device being configured to define preferential gripping areas for user gripping of an injection device when such device is located on the support surface and interfering areas for interfering with user gripping of the injection device in the interfering areas.

A self-righting device is disclosed having a support body for supporting a medicament delivery device, where the support body has a mass, a center of gravity (G) and a shape such that the self-righting device, when positioned on a substantially horizontal surface, moves from an unbalanced position to an upright position. The self-righting device can also have a mechanical adaptor configured for attachment to the support body and for holding an elongated medicament delivery device at an angle less than 30 degrees from a vertical axis when the self-righting device is in the upright position. An assembly of a self-righting device and an elongated medicament delivery device is also provided.

Disclosed herein is an auto injector for administering a medicament, the auto injector comprising: a housing; a cartridge receiver configured to receive a cartridge comprising a first stopper and a cartridge compartment containing the medicament, the cartridge compartment having a first cartridge subcompartment containing a first medicament component of the medicament and a second cartridge subcompartment containing a second medicament component of the medicament; a drive module coupled to move a plunger rod between a retracted plunger rod position and an extended plunger rod position, the plunger rod being configured to move the first stopper; a processing unit coupled to the drive module, wherein the processing unit is configured to control the drive module to move the plunger rod from a first plunger rod position to a mix plunger rod position with a mix plunger rod speed, wherein the mix plunger rod position is selected to position the first stopper in a position wherein the first medicament component is mixed with the second medicament component, and to provide an onset signal after a number of completed inversions of the auto injector has been performed.

A medicament delivery device includes a housing having a longitudinal axis, a container holder, an axially movable plunger adapted to be displaced along the longitudinal axis into the container holder, and an energy accumulating member arranged inside the housing and adapted for displacing the plunger along the longitudinal axis. The plunger includes an outer plunger rod and an inner plunger rod arranged at least partially inside the outer plunger rod, the inner plunger rod being threadedly engaged with the outer plunger rod and manually rotatable to displace the inner plunger rod along the longitudinal axis into the container holder.

Disclosed is a method for controlling an auto injector and an auto injector for administering a medicament from a cartridge having a first cartridge end and a second cartridge end and having a cartridge outlet at the first cartridge end, the cartridge comprising a cartridge compartment with a first cartridge subcompartment containing a first medicament component of the medicament and a second cartridge subcompartment containing a second medicament component of the medicament. The auto injector comprises: a housing; a cartridge receiver; a cartridge sensor; a drive module; an orientation sensor; and a processing unit.

The present disclosure relates to drug administration. In an exemplary embodiment, a system can include a drug administration device configured to dispense a drug to a patient, a monitoring device configured to log a delivery event of drug delivery from the drug administration device into the patient, and a sensor configured to sense a patient parameter following delivery of the drug into the patient. In another exemplary embodiment, a drug administration device can include a drug holder configured to hold a drug, a dispensing mechanism configured to dispense the drug, and a sensor configured to sense a patient parameter, and the drug administration device can be configured to locally activate the drug at a target location in the patient. In another exemplary embodiment, methods, devices, and systems are provided to assess when operation of a drug dispensing mechanism is complete and to confirm whether drug administration was successful.

Handheld motor-driven drug reconstitution and auto-injector device (1) having a proximal drive system (2) comprising an elongated body (3) housing a controllable drive motor (6), and an axially drivable piston rod (7), and a distal drug cartridge holder assembly (11) housing a multiple chamber (30, 31) drug cartridge (25), the cartridge holder assembly (11) being releasably attached to a distal zone (23) of the drive system (2), the drive system (2) and cartridge holder assembly (11) being configured to impart a movement to the drug cartridge holder assembly (11) in which said drug cartridge holder assembly (11) is moved from a first substantially extended distal configuration along the central longitudinal axis, to a second substantially collapsed proximal configuration along the central longitudinal axis, the relative movement of the drug cartridge holder assembly (11) effecting reconstitution of an injectable product from substances contained in each of the chambers (30, 31).

A system for producing a mixture to deliver to a treatment site. A multi-lumen chamber can be connected to a proximal end of a mixing lumen and include a first lumen aligned and adjacent a second lumen. The first lumen can be configured to include a first constituent in a proximal portion of the first lumen and a second constituent in a distal portion of the first lumen. A first plunger can be internally positioned within the first lumen to distally move the first constituent into the distal portion to mix with the second constituent in a first state to form a first mixture. The first lumen can terminate in a first port. The second lumen is configured to include a third constituent. A second plunger is internally positioned within the second lumen to distally move the third constituent and the first mixture.

The devices, assemblies, and methods described herein utilize photoacoustic principals to create a jet of fluid using a ultrasonic resonance member and a pulsed laser light beam. The ultrasonic resonance member is a treated substrate having an liquid interface surface in contact with a fluid. When a pulsed laser light beam is applied to the treated substrate, pressure is generated via induced ultrasonic waves to urge the fluid into a jet stream.

An injector (10) for injecting a medicament into a patient. The injector includes a container (18) defining a first chamber (22), which contains a fluid therein, and a second chamber (23). The injector also includes an injection conduit (126) configured for directing the fluid fired from the container into the patient. A transfer mechanism is operable by a user to transfer the fluid from the first chamber to the second chamber in a first stage of operation, and a firing mechanism is operable by the user for firing the fluid from the second chamber through the injection conduit in a second stage of operation. An energy source (62) is in powering association with the firing mechanism to drive firing mechanism in the first and second stages.