An automatic injection device including an injection syringe equipped with a syringe body and with a piston rod mounted movably in this syringe body so as to cover an injection stroke, a piston control member capable of changing between a configuration in which it is in engagement with the piston rod and a configuration in which it is disengaged from this piston rod, mechanism for moving the piston control member between its two configurations with respect to the piston rod. The mechanism for moving the control member between its two configurations includes a camway carried by a disengagement member and a cam carried by the control member. The disengagement member is movable with respect to the piston rod and the syringe body after the end of the injection stroke, in such a way as to cause the camway to interact with the cam.

The invention provides an injection device for delivering a dose of medicament from a syringe. The injection device comprises a housing (10), a plunger (110) moveably mounted within the housing, an actuation mechanism (120, 122) arranged to provide a forward biasing force to urge the plunger forward in use to express a dose of medicament and a trigger mechanism (40) arranged to (directly or indirectly) releaseably hold the plunger against the force of the actuation mechanism. The injection device further comprises a plunger velocity regulator comprising a cam surface (162) associated with one of the housing or the plunger, and a cam member (152) associated with the other of the plunger or the housing and arranged to engage the cam surface during actuation movement of the plunger such that axial movement of the plunger relative to the housing causes relative rotational movement of the cam member and limits the forward velocity of the plunger movement.

An injection device, method, and system for drug delivery includes a primary container for storing a drug, the container having a stopper movably disposed in the container for expelling the drug, an injection drive mechanism comprising a plunger for acting on the stopper and an energy source for exerting a force on the plunger to cause the plunger to act on the stopper to expel the drug, the force causing the plunger to accelerate to a velocity prior to acting on the stopper, and a damping mechanism for reducing the velocity of the plunger prior to acting on the stopper. The damping mechanism can include a dashpot or an energy absorbing material associated with the plunger. Alternatively or additionally, the damping mechanisms can include absorbing material disposed between support members of an outer casing of the injection device and the primary container.

Systems and methods for measuring and damping forces within autoinjectors in accordance with embodiments of the invention are disclosed. In one embodiment of the invention, an injection system comprises a syringe disposed within a housing, the syringe having a first end and a second end; a needle disposed at the second end of the syringe; a plunger disposed at the first end of the syringe and configured to move toward the second end of the syringe; a stopper disposed between the plunger and the second end of the syringe; a first damper disposed between the plunger and the stopper, such that the first damper is capable of damping a first event occurring between the plunger and the stopper; and a second damper disposed at the second end of the syringe, such that the second damper is capable of damping a second event occurring at the second end of the syringe.

An autoinjector includes: an insertion spring between a housing and plunger assembly; a syringe driver; a second release mechanism releasing the plunger assembly from the housing, causing the insertion spring to move the plunger assembly through the housing with a syringe driver; a stop limiting movement of the syringe driver in the housing; and a third release mechanism releasing the plunger assembly from the syringe driver upon engagement with the stop, allowing the plunger assembly to continue through the housing. The first release mechanism releases the plunger from the delivery spring housing upon contact between the plunger assembly and a bung, causing the delivery spring to separate the delivery spring housing and the plunger, applying a delivery force to a bung. A latch mechanism latches the delivery spring housing at a forward position, preventing rearward movement of the delivery spring housing following release of the plunger.

The invention provides a pen-type injection device (1) with a piston rod brake mechanism for improving the determination of an expelled dose.

A drug delivery device includes a container for storing a drug having a longitudinal axis. A plunger rod aligned with the longitudinal axis of the container has a first end and a second end, where the second end is disposed within the container. A stopper is disposed in and movable relative to the container for expelling the drug, and a drive mechanism is operatively coupled to the first end of the plunger rod. The drive mechanism is configured to deliver a drive force to move the plunger rod along the longitudinal axis and through the container. A chamber disposed between a plunger rod and the stopper is adapted to oppose the drive force of the drive mechanism.

The present disclosure relates to an assisted injection device for injecting a composition contained in a medical container. The injection device includes a body adapted to receive a medical container in a fixed position relative to the body. The injection device includes a spring-loaded piston rod translationally movable inside the body between a proximal rest position allowing inserting of the medical container in the body and a distal operative position wherein the piston rod engages a stopper of the medical container and pushes the stopper in the medical container. The injection device includes a blocking system comprising a locking member mounted on the body and configured to engage the piston rod. The piston rod includes a proximal end extending out of the body and configured to be pushed by the user in a distal direction to accelerate the movement of the piston rod to the distal operative position.

The present disclosure relates to an assisted injection device for injecting a composition contained in a medical container. The injection device includes a main body adapted to receive a medical container in a fixed position relative to the main body. The main body includes an inner wall part and a second part. The first part includes an inner spring-loaded piston rod, and an outer piston body extending coaxially around the inner spring-loaded piston rod. The second part is arranged between the inner spring-loaded piston rod and the outer piston body, and is provided of the piston. The actuator is adapted to selectively move the second part between the proximal first portion and the distal second position.

An autoinjector includes a body (1; 1010), a reservoir containing fluid product, a piston, a needle, a piston rod (5 5; 1005) that is displaceable between a loaded position and an injection position, and an injection spring (8; 1008) to stress 10 the piston rod towards the injection position. The autoinjector also includes an injection lock having a control sleeve (4; 1004) containing the piston rod and the injection spring. The piston rod includes a radial recess (50; 1050) receiving a substantially spherical blocking element (7; 1007) mobile between a blocking position and an unblocking position, stressed radially towards the exterior by the piston rod, and held in the blocking position by a blocking member (23; 1004) that is displaceable relative to the piston rod to release the blocking element.