An autoinjector having a body (1, 2), a reservoir (S) including a piston, a piston rod (5) movable between a rest position and an injection position, an actuator spring (6) urging the piston rod (5) towards the injection position, and a force-adjustment system (7, 8) to exert a force (F2) on the piston rod (5), adding to the force exerted by the spring (6) at the beginning of injection. The system has two pivot members (7) co-operating with the piston rod (5), the pivot members (7) connected together by two resilient elements (8). The body (1, 2) includes a sleeve (3), the pivot members (7) pivotally mounted on the sleeve (3) to pivot about stationary pins (79). The autoinjector includes an end-of-injection indicator that includes an indication portion movable and/or deformable relative to the body (1, 2) to co-operate with a viewing window after the end of injection.

An injection device has a plunger for displacing a stopper in a syringe or carpule, a holder for the plunger, a drive for the axial displacement of the holder of the plunger, and a control device functionally assigned to the drive. The plunger, or at least a subcomponent thereof, relative to the holder, the holder is able to move over a limited distance relative to the plunger or a subcomponent thereof, opposing a pretensioning force, in that a sensor device is included which detects the relative position of the plunger, or at least a subcomponent thereof, relative to the holder, which comprises at least one sensor element which works together with the control device. The control device is designed such that, upon activation of the sensor element, the speed of advancement of the holder of the plunger is at least reduced.

A spring assembly for an administering device includes a driving spring configured as a spiral spring and a spring shaft. An inner end of the spring is rotationally fixedly attached to the spring shaft. A spring sleeve extends around the circumferential region of the spring, wherein the outer end of the spring is connected to the spring sleeve in a rotationally fixed manner and a disk-type spring-sleeve cover is attached to the spring sleeve or the spring shaft. The flange and the spring-sleeve cover extend radially away from an axis of the spring shaft and the flange is arranged near a distal end of the spring shaft. A radial stop is arranged on the flange periphery, and a blocking element is arranged on the spring sleeve to be complementary to the radial stop for releasably rotationally securing to each other when the blocking element and the radial stop engage.

A feedback mechanism for an injection device that is configured to deliver a medicament to a user is described. The feedback mechanism comprises a piston and a fluid chamber, and the piston is adapted to move into the fluid chamber during use of the injection device. The feedback mechanism also has a damper that is arranged to damp movement of the piston, and an indicator that is arranged to provide feedback to the user after the piston has moved a pre-determined distance into the fluid chamber.

A drive assembly for a drug delivery device is provided, including a piston rod which is moveable in a distal direction in order to deliver a dose of medication, and including a drive element which is configured to cause a movement of the piston rod. The drive assembly further includes a decelerating mechanism which is configured to decelerate the movement of the drive element such that the movement of the piston rod is decelerated during the dispense of a dose. The decelerating mechanism includes a decelerating element which is fixed with respect to a housing of the drug delivery device at least during the dispense of a dose and the drive element, wherein the drive element is configured to rotate with respect to the housing during the dispense of a dose, and wherein the decelerating element and the drive element rub against each other during the dispense of a dose.

An injection device for delivering a dose of medicament from a syringe (5), the injection device comprising a housing (10), a plunger (210) moveably mounted within the housing (10), an actuation mechanism (200), a trigger mechanism (40), and a plunger velocity regulator. The actuation (mechanism (100) is arranged to provide a forward biasing force to urge the plunger (210) forward in use to express a dose of medicament, and the trigger mechanism (40) is arranged to releasably hold the plunger (210) against the force of the actuation mechanism (200). The plunger velocity regulator comprises a cam surface (262) associated with the housing, and a cam member (252) associated with the plunger (210) and arranged to engage the cam surface (262) during actuation movement of the plunger (210) such that axial movement of the plunger (210) relative to the housing (10) causes relative rotational movement of the cam member (252) which limits the forward velocity of the plunger movement. The plunger (210) is axially connected to the cam member (252) by a releasable coupling (300), and the plunger velocity regulator further comprises a coupling member (350) which blocks release of the releasable coupling (300) when the plunger (210) is in a rearward position and wherein forward movement of the plunger (210) moves the releasable coupling (300) out of engagement with the coupling member (350) such that the plunger (210) may disengage the cam member (252) after an initial movement of the plunger (210).

Systems and methods for triggering a drug injection device are disclosed. One disclosed system for injecting a substance into a patient includes: a chamber comprising a propellant; a light source mechanically coupled to the chamber, wherein energy from the light source ignites the propellant; and a power source electrically coupled to the light source via a control circuit, wherein the control circuit applies power to activate the light source.

A medicament delivery device has a drive mechanism that includes a first resilient member and a delay plunger rod assembly that includes a proximal plunger, a distal plunger, a chamber formed between the proximal and the distal plungers, an aperture, and a delay device in the chamber. The distal plunger is positioned and configured in relation to a hold and release mechanism such that, as the drive mechanism exerts a pressure on the medicament container, the distal plunger acts against the delay device, delaying a release of a signal generating member after a release of the drive mechanism to allow remaining contents of medicament in a medicament container to be completely expelled before the signal generating member is released.

An autoinjector comprising a body (1, 2), and a reservoir (S) containing fluid and including a piston (P) and a needle (A), such as a pre-filled syringe, said autoinjector further comprising a piston rod (5) that is suitable for co-operating with the piston (P) of said reservoir (S), said piston rod (5) being movable between a rest position and an injection position in which said piston rod (5) has moved the piston (P) of the reservoir (S) so as to inject the fluid through the needle (A), an actuator spring (6) being provided so as to urge said piston rod (5) towards its injection position, the autoinjector further comprising a force-adjustment system (7, 8) that exerts a force (F2) on said piston rod (5), said force (F2) adding to the force exerted by said actuator spring (6) on said piston rod (5) at the beginning of injection, so as to amplify the force exerted on said piston (P) by said piston rod (5) at the beginning of injection.

An autoinjector for dispensing a liquid product, in particular a highly viscous medication, includes: a housing, a product container, which is arranged in the housing and has a slidable piston, wherein the piston can be slid in a dispensing direction in order to dispense the product contained in the product container, a forward drive element, which acts on the piston as the product is being dispensed, a first spring, which is preloaded such that the product can be dispensed from the product container by the sliding of the forward drive element and the piston, and a rotation element, which is operatively coupled to the forward drive element, wherein the first spring acts on the rotation element in such a way that the rotation element is set into rotation in order to dispense the product, wherein the rotation element or the forward drive element has a thread having a variable pitch.