An autoinjector and method of injection are described. A power spring causes rotation of a drive nut about the central axis of the autoinjector that, in turn, causes a middle screw to rotate in the same direction as the drive nut and also to move in the distal direction while pushing a center screw in the distal direction that pushes the syringe and needle. The center screw also pushes a plunger that pushes the fluid out of the syringe. After injection, a locked retract screw is freed and rotates in the same direction as the middle screw causing the syringe to retract the syringe into the housing.

An injector device includes an elongate housing configured to receive container of medicament. The injector device also includes a needle sleeve mounted within the housing and moveable between an extended position in which the needle sleeve at least partially extends from the distal end of the housing, and a retracted position in which the needle sleeve is received further within the housing than in the extended position. The injector device also includes a release mechanism configured to control actuation of a piston rod. The release mechanism includes a rotatable member disposed within the housing and in cooperating engagement with the needle sleeve such that movement of the needle sleeve from the extended position to the retracted position causes the rotatable member to rotate within the housing from a first position to a second position.

A spring release mechanism for a drug delivery includes a fusible member to restrain a spring in a charged state. A heating element is utilized to selectively heat and sever the fusible member. When the fusible member is severed, the spring is allowed to discharge and drive the drug delivery device components operably coupled thereto.

A device (1) for dispensing a substance to a patient comprising a cylindrical first container (2) containing the substance and a second container (3) containing a liquid. The device further comprises an injection device (4) and transfer mechanism (5) for transferring the liquid from the second container (3) to the first container (2) and from the first container (2) to the injection device (4). The first container (2) has a connection element (7) and a plunger (9) that can be moved between the first (6) and second ends (8). By moving the plunger (9) towards the first end (6), liquid contained therein can be dispensed via the injection device (4). The injection device (4) comprises a piercing cannula (15) and an indwelling cannula (16). In an initial position, a distal end region of the piercing cannula (15) extends coaxially in the interior of the indwelling cannula (16).

A user-powered medicament injector including a reusable, user-powered automatic injection assembly including a user energizable medicament injection subassembly and a medicament module removably insertable into the reusable, user-powered automatic injection assembly and including a module housing adapted to receive a syringe having a barrel, a needle engaged to said barrel, and a removable needle cap covering the needle; a needle shield configured to be moveable with respect to the module housing and a needle cap remover associated with the needle shield. The medicament module is configured for energizing the user energizable medicament injection subassembly by insertion of the medicament module into the reusable, user powered automatic injection assembly.

Systems and methods for measuring and damping forces within autoinjectors in accordance with embodiments of the invention are disclosed. In one embodiment of the invention, an injection system comprises a syringe disposed within a housing, the syringe having a first end and a second end; a needle disposed at the second end of the syringe; a plunger disposed at the first end of the syringe and configured to move toward the second end of the syringe; a stopper disposed between the plunger and the second end of the syringe; a first damper disposed between the plunger and the stopper, such that the first damper is capable of damping a first event occurring between the plunger and the stopper; and a second damper disposed at the second end of the syringe, such that the second damper is capable of damping a second event occurring at the second end of the syringe.

An apparatus includes a housing, a medicament container and a movable member. The medicament container is configured to move within the housing between a first position and a second position in response to a force produced by an energy storage member. A proximal end portion of the medicament container includes a flange and has a plunger disposed therein. A first shoulder of the movable member is configured to exert the force on the flange to move the medicament container from the first position to the second position. A portion of the first shoulder deforms when the medicament container is in the second position such that at least a portion of the force is exerted upon the plunger. A second shoulder of the movable member is configured to exert a retraction force on the flange to move the medicament container from the second position towards the first position.

A container for delivering a medicament to a target location includes a housing having a proximal end and a distal end, the housing including a cap locking tab at the distal end, and a vial containing medicament. The container includes a plunger slidable within the vial from the proximal end to the distal end of the vial to dispel the medicament, an injection member associated with the distal end, such that medicament dispelled from the vial passes through the injection member to the target location, and a slidable interaction member associated with the distal end of the vial configured to slide with the vial. An interaction between the slidable interaction member and cap locking tab causes the cap locking tabs to bias outward, and placement of a safety cap on the container after use locks the safety cap onto the container via the interaction with the cap locking tabs. The container may further include a resistance feature to control movement of the plunger rod relative to the vial.

An autoinjector is provided that includes an actuator assembly having an actuator body and a relief valve assembly. The actuator body includes a receptacle, an open distal end in fluid communication with the receptacle, and a channel in fluid communication with the receptacle. The relief valve assembly includes a first timing member and a second timing member. The first timing member is movable between a primary position and a secondary position under the influence of a force. The second timing member is movable between a first position directly engaged with the first timing member and a second position spaced from the first timing member.

A medicament delivery device (100) for delivery of medicament from a container (12) into an injection site through a cannula (16). The device comprises a chassis (106), a drive mechanism (400) for driving a piston member (22) along a container axis (A) to expel the medicament through the cannula (16), and a carriage (200) for retaining the container (12), the cannula (16) and the drive mechanism (400). An insertion mechanism (70, 120, 130, 504) is provided for moving the carriage (200) in an insertion direction (H) relative to the chassis (106), and a cannula bending mechanism (300) is provided for bending the cannula (16) about a bending axis (B) to substantially align at least an end part of the cannula (16) with the insertion direction (H) prior to movement of the carriage (200) in the insertion direction (H).