An autoinjector having a reservoir containing fluid and including: a piston; a piston rod cooperating with the piston and is movable between a rest position and an injection position in which the piston rod has moved the piston to inject the fluid; an actuator spring urging the piston rod towards its injection position; a force-adjustment system exerting at least one force on the piston rod, the force adding to the force exerted by the spring on the piston rod at the beginning of injection; two pivot members cooperating with the piston rod and are connected together by two resilient elements, at least one pivot member being blocked prior to actuation by a locking system, thus preventing the autoinjector from being actuated, and an unlocking element adapted to move and/or to deform the locking system so as to unblock the at least one pivot member.

An apparatus includes a housing, a medicament container and a movable member. The medicament container is configured to move within the housing between a first position and a second position in response to a force produced by an energy storage member. A proximal end portion of the medicament container includes a flange and has a plunger disposed therein. A first shoulder of the movable member is configured to exert the force on the flange to move the medicament container from the first position to the second position. A portion of the first shoulder deforms when the medicament container is in the second position such that at least a portion of the force is exerted upon the plunger. A second shoulder of the movable member is configured to exert a retraction force on the flange to move the medicament container from the second position towards the first position.

The present disclosure relates to a medicament delivery device. The medicament delivery device includes a needle for delivering a medicament and an insertion mechanism configured to urge the needle in a first direction parallel to a longitudinal axis of the needle. The insertion mechanism includes a driving mechanism and a cam. The driving mechanism is configured to exert a force in a second direction perpendicular to the first direction. The cam is coupled to the needle and is configured to receive a force from the driving mechanism and move in the first direction in response to the received force.

An injector device includes an elongate housing configured to receive container of medicament. The injector device also includes a needle sleeve mounted within the housing and moveable between an extended position in which the needle sleeve at least partially extends from the distal end of the housing, and a retracted position in which the needle sleeve is received further within the housing than in the extended position. The injector device also includes a release mechanism configured to control actuation of a piston rod. The release mechanism includes a rotatable member disposed within the housing and in cooperating engagement with the needle sleeve such that movement of the needle sleeve from the extended position to the retracted position causes the rotatable member to rotate within the housing from a first position to a second position.

An injection device includes a drive spring within the housing, a first drive component that transfers drive from the drive spring to a plunger disposed within a medicament container, and a damper concentrically arranged with respect to the first drive component. The damper is longitudinally fixed relative to the housing. The first drive component moves along the longitudinal axis relative to the damper under the influence of the drive spring. The damper frictionally engages a surface of the first drive component during movement of the drive component relative to the damper. A method of manufacturing the injection device is also described.

Disclosed is an auto-injector for administering a medicament, comprising: a housing; a cartridge receiver configured to receive a cartridge comprising a first stopper; a drive module coupled to move a plunger rod configured to move the first stopper; a resistance sensor configured to provide a resistance signal indicative of resistance against movement of the plunger rod; and a processing unit coupled to the drive module and to the resistance sensor. The processing unit being configured to: control the drive module to move the plunger rod towards the extended plunger rod position; determine present plunger rod position; receive the resistance signal; determine a cartridge parameter based on the resistance signal and the present plunger rod position; and control the drive module to adjust the movement of the plunger rod based on the cartridge parameter.

An autoinjector having a body (1; 2), a reservoir (S), a piston (P), a needle (A), and a piston rod (5) co-operating with the piston. The piston rod is movable between a first rest position, a second pricking position, and a third injection position. An actuator spring (6) is provided to urge the piston rod towards its pricking position and then towards its injection position. A force-adjustment system (7, 8) exerts a force (F1, F2) on the piston rod (5). The force (F1) opposes the force exerted by the actuator spring at the end of pricking to decrease the force exerted on the reservoir by the piston rod at the end of pricking, and the force (F2) adding to the force exerted by the actuator spring at the beginning of injection, to amplify the force exerted on the piston by the piston rod at the beginning of injection.

An apparatus includes a housing, a medicament container, and a movable assembly. The movable assembly includes a first movable member and a second movable member. The second movable member is configured to move relative to the first movable member to move the movable assembly from a first configuration to a second configuration. A distal end portion of the second movable member is configured to move a plunger disposed within the medicament container in a distal direction when the movable assembly is moved to the second configuration. The movable assembly is configured to move between a first position and a second position to move the medicament container within the housing between a first container position and a second container position.

A medicament delivery device (100) for the delivery of medicament from a container (12) through a cannula (16). The device comprises a chassis (300), a carriage (200), and an insertion spring (70) for biasing the carriage (200) for movement in an insertion direction with respect to the chassis (300) from a starting position in which the cannula (16) is shrouded to an insertion position in which the cannula (16) is extended. A drive mechanism (400) is provided for driving the container's stopper (22) to expel medicament. The drive mechanism (400) is carried by the carriage (200) and comprises a movable drive member (404), a drive means (40) for applying a driving force to the drive member (404), and force transmission means (406) for transmitting the driving force to the stopper (22). The drive means (40) is arranged around or alongside at least part of the force transmission means (406).

An auto-injector device comprises a stopper for expelling a medicament out of a medicament reservoir; a driving element which has a first configuration and a second configuration and is configured to change shape from the first configuration to the second configuration when the temperature of the driving element is raised above a shape change temperature, so as to drive the stopper of the syringe mechanism through the medicament reservoir; and a heating mechanism configured to actively heat the driving element. The heating mechanism is a chemical heating element configured to generate heat through an exothermic process or comprises a fluid reservoir for retaining a fluid; a heater configured to heat the fluid in the fluid reservoir; a pump configured to expel the fluid out of the fluid reservoir; and a connecting conduit arranged to carry the fluid from the fluid reservoir to the driving element.