An injection device for receiving a syringe therein and for delivering a dose of medicament from the syringe, the injection device including: a driver mechanism retainable in a primed state and releasable from the primed state for driving one or more features of the injection device forwards, a trigger mechanism including a ramped surface engaged with the driver mechanism to retain the driver mechanism in the primed state, the trigger mechanism being configured on actuation thereof to withdraw the ramped surface from engagement with the driver mechanism for release thereof.

A medicament delivery device (100) for the delivery of medicament from a container (12) through a cannula (16). The device comprises a chassis (300), a carriage (200), and an insertion spring (70) for biasing the carriage (200) for movement in an insertion direction with respect to the chassis (300) from a starting position in which the cannula (16) is shrouded to an insertion position in which the cannula (16) is extended. A drive mechanism (400) is provided for driving the container's stopper (22) to expel medicament. The drive mechanism (400) is carried by the carriage (200) and comprises a movable drive member (404), a drive means (40) for applying a driving force to the drive member (404), and force transmission means (406) for transmitting the driving force to the stopper (22). The drive means (40) is arranged around or alongside at least part of the force transmission means (406).

The present disclosure relates to a medicament delivery device. The medicament delivery device includes a needle for delivering a medicament and an insertion mechanism configured to urge the needle in a first direction parallel to a longitudinal axis of the needle. The insertion mechanism includes a driving mechanism and a cam. The driving mechanism is configured to exert a force in a second direction perpendicular to the first direction. The cam is coupled to the needle and is configured to receive a force from the driving mechanism and move in the first direction in response to the received force.

Aspects of the present invention relate to an injection device comprising a housing configured to house a syringe, an activation member, a drive mechanism configured to, upon activation by the activation member, drive the plunger driver between a first, initial, position and a second, final, position thereby to operate the syringe within the housing and a damping mechanism configured to damp movement of the plunger driver in either a forward or rearward motion. In this way, tolerances in plunger position may be accounted for. Plunger position may affect the amount of travel of the plunger driver before the plunger driver is in contact with the plunger and the plunger is in contact with the drug within the barrel. During this travel, the drive force may cause rapid acceleration of the plunger driver, which may then cause damage to the syringe or discomfort to the recipient of the injection when contact between the three elements is made. Damping of the forward motion of the plunger driver reduces or overcomes the risk of this.

An autoinjector having a reservoir (100) containing fluid and a piston; a needle; a driver (200) having a body; a piston rod (210) movable between a rest position and an injection position; an injection spring (220); and a force control mechanism (280, 290) for causing the force exerted by the injection spring to vary in predetermined manner during injection, and a lever (280) and a cam (290), the lever (280) pivotally mounted on the piston rod, being connected to the injection spring (220), and co-operating with the cam; and an interface module (300) fastened to the driver that receives a reservoir (100) before each actuation. The interface module having a selector ring (310) mounted to turn on the driver module, and pivot elements (320) fastening the reservoir module in the interface module.

Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a subject. The present disclosure comprises apparatus for the controlled administration of the therapeutic agent through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.

A medicament delivery device is presented having a housing, a container assembly, a needle assembly and a driver assembly. The container assembly includes a medicament container having an interior containing a medicament. The needle assembly is connected to the container assembly and has a needle and an outer cap, wherein the outer cap is configured to be manually manipulated to move the needle toward the medicament container in order for a distal end of the needle to pierce a first seal and enter an interior of the medicament container. The driver assembly is disposed at a distal end of the medicament container and configured to be released and move the container assembly and the needle assembly toward the proximal end of the housing to an insertion position where a proximal end of the needle exits the housing.

Disclosed is an auto-injector for administering a medicament, comprising: a housing; a cartridge receiver configured to receive a cartridge comprising a first stopper; a drive module coupled to move a plunger rod configured to move the first stopper; a resistance sensor configured to provide a resistance signal indicative of resistance against movement of the plunger rod; and a processing unit coupled to the drive module and to the resistance sensor. The processing unit being configured to: control the drive module to move the plunger rod towards the extended plunger rod position; determine present plunger rod position; receive the resistance signal; determine a cartridge parameter based on the resistance signal and the present plunger rod position; and control the drive module to adjust the movement of the plunger rod based on the cartridge parameter.

An automatic injection device including an injection syringe equipped with a syringe body and with a piston rod mounted movably in this syringe body so as to cover an injection stroke, a piston control member capable of changing between a configuration in which it is in engagement with the piston rod and a configuration in which it is disengaged from this piston rod, mechanism for moving the piston control member between its two configurations with respect to the piston rod. The mechanism for moving the control member between its two configurations includes a camway carried by a disengagement member and a cam carried by the control member. The disengagement member is movable with respect to the piston rod and the syringe body after the end of the injection stroke, in such a way as to cause the camway to interact with the cam.

An autoinjection device (10′) for expelling a dose of drug is described. A housing (300) movably holds a power unit (400, 500, 550, 700) configured for driving the piston of a held container (100), the power unit comprising: a) a plunger (500) comprising a retaining geometry (515), b) a drive spring (550) arranged in a tensed state wherein a first end portion of the drive spring (550) provides a distally directed force on the plunger (500), and c) a power base (400) operably coupled to the drive spring (550) and the plunger (500), the power base (400) grounding a second end portion of the drive spring (550), wherein, in a pre-firing state of the autoinjector, a retaining element (410, 415) of the power base (400) releasably engages the retaining geometry (515) of the plunger to retain the plunger against the force of the drive spring (550), wherein the autoinjection device (10′) further defines a user operable trigger element (700) cooperating with the retaining element (410, 415) to maintain retaining engagement with the retaining geometry (515) of the plunger until triggering, and further defines an electronic module (80′) comprising a sensor (850, 851) configured to sense the shift of position of the power base (400) as it moves upon triggering.