Disclosed are hypodermic needle devices with a dose dispensing mechanism and methods of using those hypodermic needle devices. The dose dispensing mechanism, which may be an electronically-controlled pump, may be used to measure out a specific dosage amount of a drug while compensating for environmental factors, such as temperature and pressure. This allows the device to be used by patients for self-administration since a specific dosage amount of the drug may be precisely delivered regardless of the environmental conditions at the time of delivery. The specific dosage amount may be set using the device or remotely, and a fingerprint sensor may be used to prevent injecting the drug into the wrong patient.

A method for improving the accuracy of the quantity of medication injected using an injector pen, the injector pen comprising a needle, a cartridge provided with a piston and a motorized assembly for driving the piston in translation inside the cartridge, the motorized assembly comprising a pusher, the method comprising successive steps consisting of a) selecting a desired quantity of medication to be injected, b) inserting the needle into the patient body, c) moving the pusher in a forward direction in order to push the piston over a certain stroke, which is determined as a function of the desired quantity of medication selected at step a), and d) moving the pusher in a backward direction, so as to allow the piston to deform towards the pusher and take its original shape.

An actuation device for an administration device and/or an administration device for the parenteral administration of a medicament, includes a rotary element rotatable through an angle proportional to a dose volume, a pushing element configured to act on a drive, a magnetic element operatively connected to the rotary element and/or the pushing element and movable therewith relative the instrument housing, a sensor arrangement with at least three magnetic field sensors, each with a directivity with regard to the direction of a magnetic field component, and an evaluation device. At least a first and a second of the magnetic field sensors are fitted such that they selectively sense the changes in the field component in the circumferential direction and the at least third magnetic field sensor is fitted such that it selectively senses the changes in the field component in the axial direction.

An apparatus includes a housing, an actuator, a lock mechanism, and a medicament container. The lock mechanism selectively engages a portion of the housing such that (1) the lock mechanism is maintained in a substantially fixed position when the housing is in a first orientation and (2) the lock mechanism is removable from the housing when the housing is in a second orientation. The medicament container is moved in a proximal direction when the lock mechanism is removed from the housing to mix a first medicament portion contained within the medicament container with a second medicament portion contained within the medicament container. The actuator can be moved from a first position to a second position when the lock mechanism is removed from the housing to release energy stored within an energy storage member such that the medicament container is moved in a distal direction.

The invention relates to a system comprising a cassette and an auto injector for delivery of medicament. The cassette for containing the medicament comprises an index ring.

An insulin delivery system and method for dispensing a measured, user selected, amount of insulin, a derivate thereof, or another substance into an animal via a dosing module and a delivery module. The system includes a reusable dosing module. The reusable dosing module is adapted to extract a set volume of the insulin, a derivate thereof, or another substance and a set volume of the diluent from reservoir(s). The reservoir(s) optionally includes a vial, and transfers the set volume(s) to a single use, manually activated injector reservoir. The reusable injector carrier module is configured to house the single use manually activated injector reservoir and configured to provide a surface to stroke or calm the animal prior to injection.

Apparatuses, systems and methods are provided that characterize a rear sub-assembly for an autoinjector (AI). Apparatuses, systems and methods are also provided that generate injection time (IT) models for autoinjectors (AIs). Autoinjectors (AIs) (e.g., mechanical AIs, spring-loaded AIs, etc.), components for use within AIs (e.g., prefilled syringes (PFS), rear sub-assemblies (RSAs), etc.), and related methods may utilize mathematical modeling along with design for six sigma (DFSS) and design for reliability and manufacturability (DRM) to establish upstream controls that ensure injection time (IT) robustness of mechanical autoinjectors (AIs). For example, break-loose and extrusion (BLE) alert limit, rear sub-assembly (RSA) area under the curve (AUC), and RSA minimum force.

An apparatus includes a housing, an actuator, a lock mechanism, and a medicament container. The lock mechanism selectively engages a portion of the housing such that (1) the lock mechanism is maintained in a substantially fixed position when the housing is in a first orientation and (2) the lock mechanism is removable from the housing when the housing is in a second orientation. The medicament container is moved in a proximal direction when the lock mechanism is removed from the housing to mix a first medicament portion contained within the medicament container with a second medicament portion contained within the medicament container. The actuator can be moved from a first position to a second position when the lock mechanism is removed from the housing to release energy stored within an energy storage member such that the medicament container is moved in a distal direction.

A drug delivery device which includes a first housing part, a second housing part, a button, a drug expelling mechanism, a graduated plate, a circuit board and a pressing rod. The button is connected to the first housing part. The drug expelling mechanism is disposed inside the second housing part, and includes a dose setting member which is rotatable and configured to set a drug dose to be expelled. The graduated plate is disposed inside the first housing part and connected to the button, and includes a first conductive element and a plurality of second conductive element disposed on a surface thereof. The plurality of second conductive elements are arranged in interval and the first conductive element is electrically connected to the plurality of second conductive elements. The circuit board is disposed inside the first housing part and connected to the dose setting member. The pressing rod is inserted through the graduated plate, and includes an end connected to the button and the other end movable on an axial direction to trigger the actuating switch.

An apparatus includes a housing, an energy storage member, a carrier, a medicament container, and a delivery control mechanism. The housing defines a gas chamber configured to receive pressurized gas from the energy storage member to pressurize the gas chamber. The carrier has a proximal surface that defines a portion of the gas chamber. The medicament container is coupled to the carrier and has a distal end portion coupled to a delivery member. The medicament container contains at least 5 mL of medicament and includes an elastomeric member that seals the medicament within the medicament container. The delivery control mechanism is coupled to a proximal end portion of the medicament container and includes a flow restriction member for regulating a pressure supplied by the gas chamber and entering into the medicament container that acts on the elastomeric member.