The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.

A medical injection system comprising an injection module, a retract module, and a bi-directional dose setting module. The bi-directional dose setting module comprises a dose plate, and the injection module comprises a dose knob engaged with the dose plate. The medical injection system generates a first response when the dose knob is rotated in the first direction, and generates a second response when the dose knob is rotated in the second direction.

An auto injector for delivery of a medicament is disclosed. The auto injector comprises a housing, a syringe holder configured to receive a syringe; a first drive module adapted to move the syringe holder relatively to the housing; and a rigid needle shield remover comprising a first part adapted for separating a rigid needle shield from the syringe.

The disclosure relates to injectors that are configured to inject and deliver medicaments and other fluids from a syringe into a target site.

The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.

An assembly for a drug delivery device comprises a housing, a dose member which is displaceable in a proximal direction with respect to the housing for setting of a dose of a drug, a clutch member which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member configured to define a clutch stop position. The clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose.

A cassette for use in an auto injector for administering a medicament, the cassette comprises a syringe compartment containing the medicament; a hollow needle in fluid connection with the syringe compartment; a rigid needle shield connected to the syringe compartment and covering the hollow needle; a stopper movable inside the syringe compartment; a syringe holder extending around at least part of the syringe compartment; a rigid needle shield holder having a first part positioned between the rigid needle shield and the proximal end of the syringe compartment, and a cassette skin sensor. Also disclosed is the auto injector.

The present disclosure relates to a medicament delivery device including a cartridge holder to which an injection needle holder can be fixed, the injection needle holder holding an injection needle having a proximal end and a distal end, the proximal end being protected by an inner injection needle cap detachably connected to the injection needle holder, the cartridge holder being mounted in a housing and configured to receive a cartridge of medicament, a cap assembly detachably connected to the housing, and a gripping mechanism configured to remove the inner injection needle cap from the injection needle holder when the cap assembly is pulled away from the cartridge holder.

In one aspect the present disclosure relates to an injection device. The injection device includes a housing configured to receive a container; a drive mechanism having a plunger configured to urge against a bung in the container in a distal direction to expel the dose of the medicament from the container, wherein the plunger is configured to releasably connect to the bung to form a plunger bung assembly; a container moving mechanism configured to move the container relative to the housing between a proximal replacement position and a distal injection position; at least one retainer configured to prevent a proximally directed movement of the container relative to the housing. The drive mechanism is configured to retract the plunger and the plunger bung assembly along the proximal direction relative to the tubular barrel of the container.

An apparatus for tracking an amount of dispensed fluid, a system for fluid injection including the apparatus, and related methods of use are described. In an embodiment, the apparatus includes a dosage meter shaped to couple with a leadscrew and a cartridge containing a fluid for injection, and configured to track fluid injection. In an embodiment, the dosage meter includes an index wheel including a plurality of teeth, wherein the index wheel is shaped to position coaxially with a major axis of the leadscrew and to receive rotational motion from the leadscrew; and a cantilevered protrusion positioned to deflect due to contact with the plurality of teeth as the index wheel rotates coaxially with the leadscrew inducing a strain in the cantilevered protrusion, wherein the dosage meter outputs a signal indicative of the strain.