A medicament container for a syringe or carpule has a base body surrounding an interior at least in sections. The base body has a central axis and a proximal opening. An end plug is arranged in the interior such that the end plug in the interior is displaceable along the central axis and separates a first proximal region of the interior from a second distal region of the interior. A plug securing part is at least partially insertable into the second region through the proximal opening. When inserted into the interior, the plug securing part is arranged closer to the proximal opening than the end plug and is fixedly held in the interior by the positive and/or non-positive connection at least in a holding area.

A device (200) for mixing first and second substances. The device comprises a first container (100) for storage of the first substance and a second container (150) received in the first container (100) and for storage of the second substance. An outlet (112) is disposed at the distal end of the first container (100). Valve means (180) are provided for closing a distal end of the second container (150) and a proximal end of the first container (100). A stopper means (166) closes a proximal end of the second chamber (152) and is movable with respect to the second container (150). An operating mechanism drives relative movement between the first and second containers for causing displacement of the second substance into the first chamber (102) through the valve means (180) when the outlet (112) is closed, for mixing the first and second substances in a mixing stroke of the device.

The present invention provides a drug delivery device (2, 3; 102) for sequential administration of substances, comprising a first variable volume reservoir (40a; 140a) holding a first substance and comprising a first outlet (41 a, 141 a) and a first displaceable wall (43a; 143a), a second variable volume reservoir (40b; 140b) holding a second substance and comprising a second outlet (41 b; 141 b) and a second displaceable wall (43b; 143b), a first wall actuation structure (65a, 70a, 75a, 77a; 177a) activatable to move the first displaceable wall (43a; 143a) and thereby expel a dose of the first substance through the first outlet (41 a; 141 a), a second wall actuation structure (65b, 70b, 75b, 77b; 177b) activatable to move the second displaceable wall (43b; 143b) and thereby expel a dose of the second substance through the second outlet (41 b; 141 b), and a drive structure (90; 190) for activating the first wall actuation structure (65a, 70a, 75a, 77a; 177a) and the second wall actuation structure (65b, 70b, 75b, 77b; 177b). The drive structure (90; 190) performs a predetermined movement during one sequential administration of the first substance and the second substance, the predetermined movement comprising a first part movement followed by a second part movement, and is configured to activate the first wall actuation structure (65a, 70a, 75a, 77a; 177a) during the first part movement and to activate the second wall actuation structure (65b, 70b, 75b, 77b; 177b) during the second part movement.

A dose recording device (100) for a drug delivery device is disclosed, wherein the drug delivery device comprises a housing, a cartridge holder configured to receive a cartridge for holding a plurality of doses of a drug, and a dose setting member connected to the housing and configured to set the dose of the drug. The dose recording device (100) comprises a device housing (102), an electronic controller (114) disposed within the device housing (102), and at least one identifier member (120) configured to be mounted to the device housing (102). The electronic controller (114) comprises switches (116). The identifier member (120) comprises at least one actuation member (122) configured to actuate at least one of the switches (116) when mounted to the device housing (102). An actuation of the switch (116) is configured to provide additional information on the drug.

A syringe apparatus is provided for stirring and delivering single or multi-component compositions. The syringe apparatus comprises a syringe barrel, a plunger, a stirring paddle, and a connecting member. The plunger partially disposed within the syringe barrel is movable along an axial direction of the syringe barrel. The stirring paddle disposed within the syringe barrel has one end passing through the plunger and slidably disposed within the plunger. The syringe apparatus of the disclosure can stir the components and deliver the mixture safely for maintaining a good hygiene condition during the therapeutic process.

A medicine container for medicine substances which can be mixed with one another includes a container body, a stopper and a mixing element. The container body has a first end with a stopper opening and a second end with a base having an outlet. The stopper is displaceable between the ends. A mixing chamber for receiving the medicine substances is delimited by a portion of an inner casing surface of the container body, a side of the stopper and the base. The mixing element can be disposed in the mixing chamber. The medicine container is adapted to discharge the medicine substances from the medicine container by displacement of the stopper in the direction of the outlet. The stopper is adapted to receive the mixing element at least partially by a recess. The invention further relates to a method for operating such a medicine container.

A cartridge for dispensing a material, having: a sleeve having a longitudinal axis and a distal wall with a dispensing hole; a barrel defining a chamber for the material, including a proximal open end and a breakable distal wall at its distal end, and being movable in the sleeve between a first position where its distal wall is a distance from the sleeve's distal wall and a second position where its distal wall's sealing portion contacts an inner surface of the sleeve's distal wall; and a piston having a plate movable to seal the barrel's chamber. The sleeve includes an internal piercing element, near the dispensing hole, for breaking the barrel's distal wall upon moving the barrel from the first to the second position. Around the piercing element is an annular cavity delimited peripherally by a beveled inner surface that complements a beveled outer surface of the barrel.

A syringe for injecting medication into a body includes a barrel having an inner diameter, a plunger for longitudinal movement within the barrel, the plunger having threads along at least a portion thereof for engaging internal threads of a thread ring, and a handle for rotating the plunger relative the barrel. An alternate embodiment of a syringe includes a barrel having internal threads positioned along a first interior wall, a diameter of the internal threads being greater than or equal to a diameter of a second interior wall of the barrel, and a plunger in sealing engagement with the second interior wall having threads for engaging the internal threads of the barrel.

A method for mixing a first substance of a first chamber of a syringe and a second substance of a second chamber of the syringe, wherein communication of the first chamber and the second chamber is blocked by a removable member, the method including positioning the first chamber at an elevation higher than the second chamber; removing the removable member to enable communication of the first substance with the second substance to form a mixture; positioning the second chamber at an elevation higher than the first chamber; and replacing the removable member to confine the mixture in the first chamber.

A dispensing device for use with a beneficial agent has a dispensing package, a dispenser disposed on an end portion of the dispensing package, and an actuator movably disposed along at least a portion of the package between a pre-dispensing state and a dispensing state. One arrangement also provides a beneficial agent dispenser having a dispensing port, an elongate portion and a plunger that is movably disposed relative to a tubular wall of the elongate portion during a dispensing stroke to partially penetrate a separable barrier and expel the beneficial agent through the dispensing port.