A pre-filled medical delivery system can have a blow-fill-seal (BFS) module and a mixing assembly. The BFS module can have first and second chambers, first and second sealed ports, and first and second actuation members. Each chamber can have a respective liquid agent therein. Each sealed port and each actuation member can be in fluid communication with a respective one of the chambers. The mixing assembly can be constructed for coupling to the BFS module. When coupled to the BFS module, the mixing assembly can breach the seals of the first and second ports and provide fluid communication therebetween. The disclosed systems, when assembled, can combine the liquid agents from the first and second chambers of the BFS component and deliver the combination as a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) to a patient.

Mixing/administration systems and methods for preparing an agent for administration to an individual are disclosed. Caps may be included as part of the system, which may include compositions comprising at least one of a cleansing, antiseptic, antimicrobial, or disinfectant agent. The caps may additionally be included that may be used for hemostasis at an injection site. Packaging and/or the mixing/administration system within it may include a tracking mechanism for data tracking regarding many different aspects of the system, including aspects of manufacture and administration.

The present invention comprises methods and devices for generating and providing contrast medium for sonography of structures such as ducts or cavities. The invention provides for creation of a contrast medium comprising detectable acoustic variations between two phases, for example, a gas and a liquid. Sonography is the primary means of imaging but other conventional detection means may also be employed with the present invention.

The present disclosure relates to a syringe including a container, for containing a primary fluid, and at least one secondary fluid chamber configured to contain a secondary fluid. The container comprises a proximal end and a distal end and having a distal end opening at the distal end. The syringe further comprises a stopper, movably arranged within the container; and a plunger engageable with the stopper and configured to apply a force to the stopper to move the stopper within the container towards the distal end of the container, to expel primary fluid from the container through the distal end opening. The plunger is further configured to expel secondary fluid from the at least one secondary fluid chamber towards the distal end opening, to expel at least a portion of a residual volume of primary fluid through the distal end opening. A plunger system and assembly for a syringe and methods of expelling fluid from a syringe are also disclosed.

A mixing vial having a hollow interior chamber with a tubular portion having distal and proximal open ends and a stopper positioned in sealing relationship in the tubular portion, the stopper having a hollow interior chamber with an open end and a dislodgeable plug positioned in and sealing the open end.

One aspect relates to a device for mixing two liquids including a tube having an open end, a main line connected to the tube in a liquid-permeable manner, a rubber-elastic body delimiting a line wall of the main line, at least one secondary line in the rubber-elastic body, wherein the at least one secondary line extends from at least one secondary opening up to the main line and opens via at least one mouth into the main line, a main connection for introducing a first liquid into the main line, at least one feed line for introducing a second liquid into the at least one secondary line, which is connected to the at least one secondary opening in a liquid-permeable manner. The at least one secondary line is closed in the rubber-elastic body without the action of a force and is hydraulically openable by a pressure being exerted on a second liquid fed to the at least one secondary line by an elastic deformation of the at least one rubber-elastic body. The open at least one secondary line closes without a pressure being exerted on the supplied second liquid by the restoring force of the elastically deformed rubber-elastic body.

A gas mixture apparatus includes a measurement control system, an activation system, a pressurized chamber with one or more gases, and a mixing chamber. A filter can be preattached to the outlet of the mixture apparatus, allowing excess gas to be discharged therethrough and then atmospheric air to be drawn into the mixture apparatus through the filter for creating a therapeutic gas mixture.

The present disclosure provides devices, kits and methods for preparing injections with cells and carrier components for delivery to a target area in the body. The disclosed devices, kits, and methods provide preparation and monitoring of injections.

The present invention improves the feeling in use when a finger is hooked on a finger grip. This syringe is provided with a cylinder 22, a syringe needle 24, a finger grip 30, and a plunger rod 32. The finger grip 30 is provided with a cylindrical portion and a pair of finger hook portions. The finger hook portion has an inclined curved surface 70 and an end-side curved surface 72. The inclined curved surface 70 is disposed on a side, of a side surface of the finger hook portion, connected to the cylinder 22. In the inclined curved surface 70, the inclination of a base-side region with respect to the center axis of the cylindrical portion is gentler than the inclination of an end-side region with respect to the center axis of the cylindrical portion. The end-side curved surface 72 is disposed at the boundary between the end of the finger hook portion and the inclined curved surface 70. The end-side curved surface 72 extends along the boundary.

A dispensing device for use with a beneficial agent has a dispensing package, a dispenser disposed on an end portion of the dispensing package, and an actuator movably disposed along at least a portion of the package between a pre-dispensing state and a dispensing state. One arrangement also provides a beneficial agent dispenser having a dispensing port, an elongate portion and a plunger that is movably disposed relative to a tubular wall of the elongate portion during a dispensing stroke to partially penetrate a separable barrier and expel the beneficial agent through the dispensing port.