The present invention relates to a method for producing a sterile oxybutynin-comprising composition in a preferably ready-to-use piston syringe or for producing a preferably ready-to-use sterile piston syringe filled with an oxybutynin-comprising composition as well as a sterile oxybutynin-comprising composition and piston syringe as such.

There is provided drug delivery devices comprising a drug container assembly with a needle and automatic needle insertion and drug delivery mechanisms. Aspects of the devices described include a noise-generation mechanism to indicate the completion of drug delivery, a mechanism for triggering drug delivery following needle insertion, front-end activation of the device and a safety mechanism for covering the needle after use and methods of assembly of the devices.

There is provided drug delivery devices comprising a drug container assembly with a needle and automatic needle insertion and drug delivery mechanisms. Aspects of the devices described include a noise-generation mechanism to indicate the completion of drug delivery, a mechanism for triggering drug delivery following needle insertion, front-end activation of the device and a safety mechanism for covering the needle after use and methods of assembly of the devices.

Embodiments disclose a disposable protective assembly apparatus for a dental syringe body of a dental syringe. The apparatus is a combination of a disposable syringe tip and a disposable protective sleeve, the sleeve being pre-attached to the syringe tip, and the sleeve being in a pre-folded position to be quickly and easily slid over the dental syringe prior to a dental operation.

A syringe assembly includes a plunger assembly, a syringe body, and a needle. The plunger assembly includes a plunger rod, a spring, a plunger base, and a plunger plug. The plunger rod includes a first end member having a first stepped part positioned in an inner wall thereof, a second end member, and a first accommodating room. The plunger base includes a plunger body, a projection, a second stepped part, a plunger member, and a locating member. The plunger body is received in the first accommodating room, and the projection abuts against the first end member. The spring is arranged around the plunger body and positioned between the first stepped part and the second stepped part. The plunger plug is mounted to the second end member, and defines a fixing groove. The syringe body includes a needle cannula, a needle base, a fixing pole, and a fixing valve. The plunger assembly is received in the needle cannula. The needle base is mounted to the needle cannula. The fixing valve is received in the needle base. The fixing pole is received in the fixing valve and protrudes out of the needle base. The needle is received in the fixing pole. The syringe assembly of the present invention is prevented from reuse and accidently damage because the needle can retract into the plunger rod using restoring force of the spring.

Mixing/administration systems and methods for preparing an agent for administration to an individual are disclosed. Caps may be included as part of the system, which may include compositions comprising at least one of a cleansing, antiseptic, antimicrobial, or disinfectant agent. The caps may additionally be included that may be used for hemostasis at an injection site. Packaging and/or the mixing/administration system within it may include a tracking mechanism for data tracking regarding many different aspects of the system, including aspects of manufacture and administration.

The present invention provides a needle unit (10, 310, 410, 510) having a proximal space (13, 513) adapted to accommodate a portion of a variable volume reservoir, the needle unit (10, 310, 410, 510) comprising: a needle carrier (15, 315, 415, 515), a needle tube (21, 121, 221, 321, 421, 521) being fixed to the needle carrier (15, 315, 415, 515) and comprising a distal needle end (23, 123, 223, 323, 423, 523) for providing fluid communication to an injection site, a needle shield (50, 350, 450, 550) carrying a sealed chamber (38, 138, 238, 338, 438, 538) for accommodating a distal portion of the needle tube (21, 121, 221, 321, 421, 521), the sealed chamber (38, 138, 238, 338, 438, 538) being sealed distally by a penetrable self-sealing septum (39, 139, 239, 339, 439, 539), and a flow channel (24, 124, 224, 324, 424, 524) for establishing fluid communication between the sealed chamber (38, 138, 238, 338, 438, 538) and the proximal space (13, 513), wherein the needle shield (50, 350, 450, 550) and the needle carrier (15, 315, 415, 515) are capable of relative motion between a first relative position in which the sealed chamber (38, 138, 238, 338, 438, 538) houses the distal needle end (23, 123, 223, 323, 423, 523), and a second relative position in which the distal needle end (23, 123, 223, 323, 423, 523) protrudes from the sealed chamber (38, 138, 238, 338, 438, 538) through the penetrable self-sealing septum (39, 139, 239, 339, 439, 539), and wherein the needle tube (21, 121, 221, 321, 421, 521) further comprises a side hole (25, 125, 225, 325, 425, 525), the side hole (25, 125, 225, 325, 425, 525) being in fluid communication with the flow channel (24, 124, 224, 324, 424, 524) and positioned within the sealed chamber (38, 138, 238, 338, 438, 538) when the needle shield (50, 350, 450, 550) and the needle carrier (15, 315, 415, 515) are in the second relative position.

Embodiments disclose a disposable protective assembly apparatus for a dental syringe body of a dental syringe. The apparatus is a combination of a disposable syringe tip and a disposable protective sleeve, the sleeve being pre-attached to the syringe tip, and the sleeve being in a pre-folded position to be quickly and easily slid over the dental syringe prior to a dental operation.

A medicament injection device includes a main body configured to receive a medicament cartridge sealed by a penetrable barrier, a cap assembly having an inner needle part and an outer needle part, wherein the inner needle part is movable in a proximal direction with respect to the outer needle part, a needle carrier carrying a needle, the needle carrier being releasably coupled to the inner needle part, wherein, when the inner needle part is displaced in the proximal direction, the inner needle part causes the needle carrier to be displaced axially in the proximal direction, and wherein, subsequent to the axial displacement of the inner needle part, the cap assembly is separable from the main body by movement of the cap assembly in a distal direction.

A sealed and cryoresistant device for injecting a solution, the device being designed to be associated with a needle for subsequent injection of the solution and including an injection body, a plug and a plunger head. The injection body includes a first, proximal end closed in a sealed manner by the plunger head and a second, distal end closed in a sealed manner by the plug. The plug is held on the injection body by a fastening and includes a breakable portion allowing a needle to be mounted, the plug being a divisible plug, the separation of a divisible portion releasing an element for fastening an injector including a needle. The materials forming the device are cryoresistant.