A drug delivery device and cartridge wherein the cartridge includes a movable use indicator that indicates whether the cartridge has been opened and/or used.

The present disclosure is directed to pharmaceutical packaging such as syringes, vials, and blood tubes having a thermoplastic wall that is coated with a gas barrier coating in which at least one layer is applied by atomic layer deposition. The gas barrier coating may include, for example, one or more layers of SiO.sub.2, one or more layers of Al2O3, or a combination thereof, and may serve as a barrier against a variety of gases including oxygen, water vapor, and nitrogen. The present disclosure is also directed to syringes and vials which are configured for the storage of lyophilized or cold-chain drugs and in particular to maintain container closure integrity throughout the supply and storage conditions associated with such drugs. The present disclosure is also directed to evacuated blood tubes having extended shelf lives.

A syringe assembly having a barrel for storing a medication and a stopper positioned within the barrel and having an opening, the stopper separating the proximal and distal sections of the barrel. A plunger is movable axially within the barrel. A cover extends radially from the plunger, the cover movable within the barrel from an open position to a closed position, wherein in the open position the cover exposes the opening in the stopper to enable the medication to flow within the barrel from the proximal section to the distal section and in the closed position the cover covers the opening to prevent the flow of medication from the proximal to the distal section.

A reduced profile syringe assembly is provided that includes an overall profile that is substantially similar to a profile of a syringe barrel. The syringe assembly includes a plunger rod that is significantly disposed within the syringe barrel when filled for use, with the plunger rod adapted to be retracted from the syringe barrel during dispensing of contents of the syringe barrel.

Medical devices capable of filling liquid into a syringe barrel while evacuating any air from the syringe are described. An exemplary medical device includes a syringe barrel having a tapered sidewall portion for permitting air to vent from the chamber and preventing liquid from exiting the chamber, a plunger rod, and stopper. Another exemplary medical device includes a syringe barrel having a plurality of air venting grooves associated with the sidewall of the barrel, a plunger rod and stopper. Also described is a medical device including a syringe barrel, plunger rod and stopper having a porous plug. Described is a medical device including a syringe barrel having a plurality of air venting grooves associated with the sidewall of the barrel and a porous membrane disposed over the air venting grooves, a plunger rod and stopper. Methods for filling a syringe barrel with a liquid are also provided.

A syringe adapter includes a housing having a first end and a second end positioned opposite the first end, with the housing including a connector body positioned at the first end of the housing and configured to be secured to a syringe barrel, a cannula positioned within the housing, with the cannula defining a transfer opening and a valve opening, a seal arrangement positioned within the housing and movable within the housing, and an aspiration assembly comprising an aspiration housing defining an aspiration opening, a filter received by the aspiration housing, and one-way valve received by the aspiration housing, where the valve opening of the cannula is positioned within the aspiration housing, and where air is configured to flow into the filter via the aspiration opening, into the one-way valve, and into the valve opening of the cannula.

A system and method of humanely dosing a human or animal with a formulation at a distance. A system capable of dosing a recipient with a formulation having a mass between 10 and 500 grains propelled at low-to-medium ballistic velocities (300 to 800 feet per second) and with medium-to-long range ballistic accuracy (10 to over 100 yards) without causing serious physical harm to, nor the death of, the recipient.

A transfer device for living organisms is used for placing an object in a living organism. The transfer device for living organisms includes a tubular needle extending in one direction, and a pushing member located inside the needle. The needle is configured to capture an object therein from an opening at a tip of the needle. The pushing member is configured to be movable relative to the needle from inside the needle toward the opening.

A method of delivering epinephrine includes placing a distal end surface of a medical injector into contact with a target location of a patient. The medical injector includes a housing, an energy storage member, and a medicament container containing a dose of epinephrine effective for administration to the patient experiencing anaphylaxis and having a weight of less than 15 kg. The medicament container is coupled to a needle. The medical injector is actuated such that the energy storage member produces a force to move the needle from a first needle position to a second needle position. A distal tip of the needle extends from the distal end surface by a distance of between 7 millimeters and 8 millimeters when the needle is in the second needle position. A portion of the force is exerted to expel the dose of epinephrine when the needle is in the second position.

An air bubble removal cap includes: a main body portion that is formed in a tubular shape and defines a hollow portion inside, the hollow portion being configured to communicate with a collection tube that accommodates a body fluid from a living body; a connection portion that is located on a proximal side of the hollow portion and to which the collection tube is connectable; an exhaust portion that is located on a distal side of the hollow portion and is configured to discharge gas discharged from the collection tube; a filter that is disposed in the hollow portion and divides the exhaust portion and the connection portion; and a scattering prevention mechanism that covers a proximal side of the filter and prevents the body fluid from scattering to the filter.