A syringe cover device comprises a first cap with a first frame and a first seal coupled thereto, and a second cap with a second frame and a second seal coupled thereto. The first frame and the second frame are couplable to each other to form an accommodating space therebetween. The first seal and the second seal are couplable to each other to form a main seal body and disposed in the accommodating space. The main seal body has a first surface abutting against the first frame and the second frame, a second surface opposite to the first surface and an aperture formed through the first surface and the second surface. The first frame and the second frame may be attached to a syringe flange with the syringe plunger passing through the aperture to cover and seal a back opening of the syringe barrel.

Various systems and methods for the pressure-regulated transfer of medical fluids are disclosed. The system can include an adapter assembly that connects with a medical container and with a syringe assembly. The syringe assembly can include a first reservoir and a second reservoir. In various embodiments, when the adapter assembly and the syringe assembly are coupled, the first reservoir and the container can exchange regulating fluid and the second reservoir and the container can exchange medical liquid from the medical container.

Various systems and methods for the pressure-regulated transfer of medical fluids are disclosed. The system can include an adapter assembly that connects with a medical container and with a syringe assembly. The syringe assembly can include a first reservoir and a second reservoir. In various embodiments, when the adapter assembly and the syringe assembly are coupled, the first reservoir and the container can exchange regulating fluid and the second reservoir and the container can exchange medical liquid from the medical container.

An injector includes a housing having a syringe assembly and an actuating mechanism at least partially disposed within the housing. The syringe assembly includes a syringe barrel that stores a medicament to be injected into a user, a needle assembly, and a filter member disposed adjacent to the needle assembly. The actuating mechanism is operatively coupled to the syringe assembly and includes a torque spring that exerts a torque to urge the medicament through the filter member to be injected into the user. The actuating mechanism further includes a damper mechanism that exerts an opposing force to dampen the motion exerted by the torque spring.

Apparatus and methods for medicament delivery. The apparatus may include, and the methods may involve, a delivery device for delivering a target amount of the medicament from a distal end of the device. The device may include a rod for moving a plunger that discharges the medicament from the distal end. The device may avoid or reduce deformation of the plunger during the discharge. The plunger motion may be stopped by detent that interacts with the rod. The apparatus and the methods may provide an operator indication of progress of stages of operation. The device may feature triggers corresponding to stages of medicament displacement from the device, such as pre-delivery stages, including priming.

A fat conditioning apparatus includes a conditioning vessel enclosing a conditioning chamber and a displacable plug. The conditioning chamber is bounded on one end by the displacable plug and has a variable volume that is a function of the position of the plug within the conditioning vessel. The apparatus has utility in a fat conditioning method, wherein the conditioning chamber contains a harvested fat emulsion. A washing liquid is injected into the conditioning chamber and mixes with the harvested fat emulsion, thereby displacing the plug in an outward expansion direction and expanding the variable volume of the conditioning chamber. The resulting mixture of harvested fat emulsion and washing liquid is stratified in the conditioning chamber into a contaminant-lean fat fraction and a contaminant-rich remainder fraction. The fat fraction, which is substantially free of the remainder fraction, is recovered from the conditioning chamber as a desired product of the method.

A disposable syringe for use with a pneumatic driver. The syringe has an elongated barrel with a cap secured to the proximal end that has a through bore. A filter is secured to the cap interior of the barrel that covers an opening in the through bore interior of the barrel. The pneumatic driver includes a source of pressurized air; a support for receiving and locating the syringe; and a supply block configured to receive pressurized air from the source and having an outlet for delivery of pressurized air. The supply block is movable between a first position spaced apart from the cap of the syringe and a second position in contact with the cap with fluid communication being established between the outlet of the supply block and the through-bore in the cap.

A composite media includes a stack with 20 or more layers, each layer including a substrate with a first major surface and an opposing second major surface; and a fiber layer deposited onto the first major surface of the substrate and including polymeric fibers with a diameter of 100 nm to 1.5 μm. Each fiber layer independently has a thickness of 5 μm to 100 μm, and each layer independently has a pore size of 0.1 μm to 10 μm. A filter may include a housing and the composite media disposed within the housing. The filter may be a syringe filter.

Medical device assemblies capable of aspirating liquid into a syringe barrel or other medical devices while evacuating any air from the syringe are described. An exemplary medical device includes a syringe barrel, plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within either the stopper or the plunger rod. Described is a medical device including a syringe barrel, plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within chamber between the stopper and plunger rod wherein the plunger rod includes a sealing edge and is moveable relative to the stopper. Exemplary medical devices may include a vent for allowing air that permeates through the porous portion to escape to atmosphere. Methods for aspirating a syringe barrel with a liquid are also provided.

Provided herein are devices, systems, and methods for the removal of preservatives/excipients/stabilizers from pharmaceutical preparations/medicaments. The devices and systems include a resin for the filtering of preservatives from pharmaceutical preparations. The methods allow for a period of time of incubation of the pharmaceutical preparation in the resin that effectively removes preservatives, while at the same time maintaining the required amount or concentration of active compound in the preparation. Also provided herein are devices, systems, and methods for the controlled release of anti-inflammatory agents in an insulin infusion set.