A calibration system for calibrating a pressure output of a fluid injector having a housing configured for connecting to the fluid injector; a drive member engagement portion configured for contacting a drive member of the fluid injector; a compressible member, which may have a known modulus of compression, connected at its proximal end to the drive member engagement portion, wherein the compressible member is compressed with movement of the drive member of the fluid injector between a first, uncompressed position and a second, at least partially compressed position of the fluid injector in a distal direction; and a sensor connected to the compressible member is described. The sensor is configured for measuring at least one of a force imparted by the drive member and a displacement of the drive member when the compressible member is in the second, at least partially compressed position. The system may generate a calibration curve for the drive member of the fluid injector and allow the generation of a fault condition. Methods for calibrating a fluid injector are also described.

A medical injector including a cap remover or second cap is disclosed. The medical injector includes an injector housing defining a reservoir, a plunger rod, and a stopper engaged with a portion of the plunger rod and slidably disposed within the reservoir. The stopper being sized relative to an interior of the injector housing to provide sealing engagement with a sidewall of the injector housing. The medical injector further includes a needle having a sharpened first end and a second end in communication with the reservoir, a first cap covering the sharpened first end of the needle, and a second cap covering at least a part of the first cap. The second cap is engaged with the first cap such that removal of the second cap simultaneously removes the first cap from the first end of the needle.

A protective assembly includes a body for receiving the syringe; and a coupling device inside the body, rigidly connected to the barrel as regards to axial movement relative to the body. The coupling device includes an attaching element which can be either in an engaged state to axially fix the coupling device and the plunger rod, or in a release state in which the coupling device and the plunger rod are axially free relative to one another. The coupling device is axially movable in the body from a storage position to an injection position in which the needle extends beyond the body, and in which the attaching element can move towards the release state. The coupling device is axially movable in the body from the injection position towards a safety position, in which the needle is covered by the body.

A syringe assembly includes a substantially cylindrical syringe barrel including a fluid dispensing end, an open end, and at least one protrusion adjacent the open end, the at least one protrusion projecting inwardly from an inner surface of the syringe barrel, a stopper configured to be received within the open end of the syringe barrel, and a plunger rod having a plunger rod body extending along a longitudinal axis from a proximal end to a distal end and at least one support disk provided on the distal end thereof. The support disk on the plunger rod is configured to bear against the protrusion of the syringe barrel upon misalignment of the plunger rod in the syringe barrel.

An automatic injector dispenses a predetermined dose of medicament without a user having to manually force the needle into an injection site. The automatic injector includes a needle cover having a locked retracted position with respect to the injector housing prior to a medicament dispensing operation. The needle cover is operative to engage an injection site prior to a medicament dispensing operation.

The invention relates to an apparatus (2, 3), comprising a mating unit (20-1, 20-2) for releasably attaching the apparatus (2) to a medical device (1) or for releasably receiving at least a part of the medical device (1). The apparatus (2, 3) further comprises one or more optical sensors (25, 26) and/or one or more acoustical sensors (27) for determining information related to a condition and/or use of the medical device (1). The invention further relates to a system comprising such an apparatus (2, 3) and such a medical device (1), to a method (500, 600, 700) and a computer program (61) for determining information related to a condition and/or use of such a medical device (1), and to a computer-readable medium (60) storing such a computer program (61).

The present disclosure relates to a dosing mechanism for a drug delivery device for selecting and dispensing a number of user-variable doses of a medicament. The dosing mechanism comprises a housing, a piston rod, and a driving mechanism for rotating the piston rod and/or a movement application component, which is directly engaged with the piston rod, in a dispense rotational direction with respect to the housing for dose dispense. The dosing mechanism further comprises a rotational end stop mechanism for terminating dose dispense with a first engagement means, which is rotationally fixed with respect to the piston rod and/or the movement application component, and a second engagement means, which is prevented from rotation with respect to the housing in the dispense rotational direction at an end of dose dispense. In order to improve the dose delivery accuracy, the second engagement means directly engages the first engagement means. disclosure

Devices and methods are disclosed that provide a syringe actuator device for use in the distention and irrigation of a body conduit before the use in a medical procedure such as a coronary bypass graft procedure. The device can be retrofit to a syringe by attaching it to the cap of the plunger and engaged to automatically apply pressure to fluid in the syringe. In some embodiments, elastic bands attached to the device are easily engaged or removed from a syringe during a procedure to limit the pressure on the syringe to various levels. The device may be overridden by an operator pushing on the plunger of the syringe as in normal syringe operation.

An apparatus (100) for use with an auto-injector configured to receive a syringe and comprising: a firing assembly (102) comprising a rearward portion (108), a plunger rod (110) moveable forward relative to the rearward portion (108) and a plunger rod driver (112) configured to drive the plunger rod (110) forward relative to the rearward portion (108); an insertion driver (106) configured to drive the syringe forwards on an insertion stroke for inserting a needle of the syringe into an injection site; and wherein the firing assembly (102) further comprises a retainer (114) engaged with the plunger rod (110) and/or the rearward portion (108) and configured to prevent forward movement of the plunger rod (110) relative to the rearward portion (108), and to disengage from the firing assembly (102) at a point on the insertion stroke.

A medicine injection pen includes a rotatable drive member and a rotary encoder associated with the drive member. The rotary encoder is configured to determine an amount of liquid medicine dispensed based on a rotational orientation of the drive member.