Drug delivery systems, devices and methods of use for recording a drug dose completion signal in a data management system are provided. Aspects of the invention include drug delivery systems comprising a syringe stopper rod that comprises a sensor component comprising a wireless transmitter module and an activation component configured to activate the sensor component when the syringe stopper rod has completed a delivery stroke, wherein the wireless transmitter module is configured to transmit a report comprising a drug dose completion signal when the sensor component is activated.

A delivery device for delivering a medical fluid to a patient has a housing configured for receiving a container at least partially filled with the medical fluid. The delivery device further has a drive mechanism associated with the housing configured for delivering the medical fluid from the container to the patient in a dosing procedure. The delivery device further has a module configured for detecting at least one of a property of the dosing procedure and a property of the medical fluid. The module has at least one dose detection sensor configured for detecting an initiation, progression, and completion of the dosing procedure based on a position of a stopper within the container. The module further has at least one temperature sensor configured for measuring a temperature of the medical fluid within the container based on a temperature of the container.

A drug delivery device includes a container for storing a drug having a longitudinal axis. A plunger rod aligned with the longitudinal axis of the container has a first end and a second end, where the second end is disposed within the container. A stopper is disposed in and movable relative to the container for expelling the drug, and a drive mechanism is operatively coupled to the first end of the plunger rod. The drive mechanism is configured to deliver a drive force to move the plunger rod along the longitudinal axis and through the container. A chamber disposed between a plunger rod and the stopper is adapted to oppose the drive force of the drive mechanism.

An injection-device and an injection-measuring method are described. The injection-device includes a pen-type sleeve for accommodating a cartridge holder, a mechanical injection system provided in the pen-type sleeve, which has a dosing sleeve by which a dosage quantity to be injected is predefinable and which is configured to execute a rotatory motion during the injection process; a selector device, connected to the dosing sleeve, for adjusting the dosage quantity to be injected; an injection button, connected to the selector device, for applying an injection force; and an optical sensor device for detecting the rotatory motion of the dosage sleeve during injection of the dosage quantity, which has a signal-processing device for ascertaining and storing the injected dosage quantity based on the detected rotatory motion of the dosage sleeve. The injection button has a switch device by which the optical sensor device is activatable when applying the injection force.

A method of adapting an auto injector configured to actuate a prefilled syringe, the auto injector having a biasing member having a spring constant, the prefilled syringe being filled with a volume of therapeutic fluid, the prefilled syringe including a barrel, stopper, and a needle, the stopper having a path of travel, the biasing member arranged to move the stopper along the path of travel. An auto injector having an injection spring adapted to an aged prefilled syringe.

A fat suction and graft syringe includes a negative pressure adjustment mechanism. The negative pressure state in a barrel can be maintained during a procedure only by pulling and releasing a plunger, and only by slightly rotating the plunger. The plunger can be pushed inside the barrel without being constrained by a multi-level holding plate and a single-surface rotation clip, whereby the syringe has enhanced convenience in the use and production thereof so that many practitioners accustomed to using a normal syringe can easily use the syringe without separately learning how to manipulate the syringe.

A syringe with an integrated guidewire tract. The tract provides a physical channel by which a guidewire is guided through the syringe structure. The syringe is configured to allow for a one-handed aspiration operation or injection operation, while freeing the other hand to move the guidewire through the guidewire tract of the syringe system.

A double barreled injector assembly for performing multiple sequential vaccinations includes a pair of barrels, each of which is engaged by a first terminus thereof to a bar and extends from a lower face thereof. A respective agent can be positioned in each barrel. Each barrel has an orifice positioned in a second terminus thereof. A pair of actuators is engaged to an upper face of the bar. Each actuator is operationally engaged to a respective barrel and can be actuated by action of a hand of a user to dispense an associated agent through the orifice of the respective barrel into an animal. The injector assembly allows the user to perform multiple sequential vaccinations with two different vaccines and will be useful in vaccination of herds or flocks of livestock, such as poultry, cattle, and the like.

The invention relates to a spring driven multi-use fixed dose injection device with an End-of-Content (EoC) mechanism. A housing structure contains a volume of a liquid drug which is expelled in a predefined number of substantially equally sized dose volumes. Each dose volume is expelled automatically with the assistance of a spring which is loaded with a force sufficient to expel the full number of the predefined plurality of predetermined and equally sized dose volumes. Each dose volume is prepared and released by moving a drive element a predetermined axial distance in the proximal direction away from an initial position, followed by a rotation of the drive element by the force of the spring back to the initial position during which rotation the drive element rotates the piston rod to move helically. The End-of-Content mechanism determines how many times the drive element can be moved proximally and comprises a longitudinal track structure associated with the piston rod which has a free length defined by a proximal stop associated with the piston rod which stop prevents the drive element from moving an additional predetermined axial distance in the proximal direction required to prepare a subsequent predetermined dose volume after the predefined plurality of predetermined and equally sized dose volumes have been selected.

A drug delivery device (100, 200) for delivering a fixed dose, wherein the drug delivery device comprises: a housing assembly, a drug reservoir with a piston and a drive mechanism. The drive mechanism comprises a piston rod (109, 209) for advancing the piston to expel a drug, and a drive tube (180, 280), wherein the drive mechanism is adapted to deliver the predefined fixed dose in response to activation. The drug delivery device further comprises an activation mechanism for activating the drive mechanism, in response to moving the drive tube in an axial direction. The housing assembly comprises a guide structure for guiding the drive tube during activation and delivery of a dose, wherein the guide structure comprises an axial portion (156, 256) providing a sliding surface for guiding the drive tube during activation, and for providing a rotational stop defining an end of dose, and a helical portion (157, 257) providing a sliding surface adapted for guiding the drive tube (180, 280) during dosing. The drive tube (180, 280) comprises a guide structure comprising an axial portion (182, 282) adapted for slidably engaging the axial portion of the housing assembly for activation, and a helical portion (189, 289) for slidably engaging the helical portion of the housing assembly during dosing during dosing.