The invention according to the present document discloses a device 1 configured for conveying a toxic aerosol from a drug contained in a syringe (S) or in a vial (F) toward a suction pipe, comprising a cylindrical hollow element comprising an inner space configured for accommodating a syringe so that the inner walls of said space slidingly adhere to the outer walls of the syringe barrel, provided with a proximal end 2.10 which includes an opening 2.6 configured in such a way as to allow the insertion of a syringe barrel, and a flange configured for accommodating a syringe flange, and a distal end 2.11 which includes an opening 2.7 configured in such a way as to allow the cone, fitting, and needle of said syringe to pass through, and a cap configured for being connected to said cylindrical hollow element present in two configurations, one suitable for administering a drug and another suitable for taking a drug from a vial, in particular a drug potentially releasing a toxic aerosol.

The document also discloses a method for using the kit and the device according to the invention.

An autoinjector includes a housing, a product container, a torsion spring, a drive element, and a propulsion element. In order to discharge liquid out of the product container, the torsion spring rotates the drive element, and the rotating drive element produces a propulsive movement of the propulsion element and of a piston in the product container. A rotation sensor is configured for an alternating continuous detection of at least two rotational positions per revolution of the drive element during the discharge process, and a processor unit is configured for determining the axial position of the piston in the product container from the detected rotational positions.

An autoinjector for discharging one or more liquid products includes: a housing containing a multichamber product container, which includes a syringe body and an injection needle rigidly arranged at the distal end of the syringe body. The syringe body includes a first chamber for a first liquid product, a second chamber for a second liquid product, and a bypass for fluidically connecting the first chamber and second chamber. The bypass is formed in or on the syringe body in the form of a curved section protruding radially outwards, and two plungers are arranged in the syringe body in an axially movable manner.

Provided are an apparatus and method for injection of a fluid into a substrate. In some embodiments, an apparatus or method described herein delivers cells to a tissue scaffold, graft, or site of tissue injury to facilitate the repair of a tissue defect.

A hollow needle includes a needle body made of an electrically conductive material, forming a cylindrical shape, and including a shaft part, a tip part connected with the shaft part, and an opening for discharging or drawing in a liquid in which a cavity communicating between the shaft part and the opening is formed. Also included is an annular insulating film made of an electrically insulative material, which exposes the opening and at least part of the tip part, and coats at least part of an outer circumferential surface of the shaft part.

An exchangeable cartridge for an injection device is disclosed. The cartridge (3) comprises a container (4) and a plunger (10) connectable with a plunger rod (9). The container receives the plunger rod from its rear end. The plunger comprises a rod connector (12) connectable with a front portion (13), and the rod connector has a base portion (24), an outer wall section (15), an inner wall section (16), and a rod stop portion (17) encircled by the inner wall section. The inner wall section comprises several tongues (22) protruding rearwards from the base portion and defining an entrance opening (18) for the plunger rod. The inner wall section receives a front portion (13) of the plunger rod through the entrance, and the tongues are provided with retaining portions arranged to retain the front end portion during retraction of the plunger rod within the housing.

A vial adaptor can include a connector interface and/or a piercing member. The vial adaptor can include a regulator assembly. The regulator assembly can include a regulator base, a regulator nest coupled with the regulator base, and/or a storage chamber formed at least partially by one or both of the regulator base and regulator nest. The regulator assembly can include a cover connected to one or both of the regulator base and regulator nest and fitted around a radially outward portion of one or both of the regulator base and regulator nest. In some cases, the regular assembly includes a flexible enclosure connected to the regulator nest and configured to transition between a contracted configuration and an expanded configuration. In some cases, the flexible enclosure is inhibited from transitioning to the expanded configuration prior to removal or modification of the cover from the regulator assembly.

A vial adaptor can include a connector interface and/or a piercing member. The vial adaptor can include a regulator assembly. The regulator assembly can include a regulator base, a regulator nest coupled with the regulator base, and/or a storage chamber formed at least partially by one or both of the regulator base and regulator nest. The regulator assembly can include a cover connected to one or both of the regulator base and regulator nest and fitted around a radially outward portion of one or both of the regulator base and regulator nest. In some cases, the regular assembly includes a flexible enclosure connected to the regulator nest and configured to transition between a contracted configuration and an expanded configuration. In some cases, the flexible enclosure is inhibited from transitioning to the expanded configuration prior to removal or modification of the cover from the regulator assembly.

An auto-injector for administering a dose of a liquid medicament (M) is presented having an elongate case, a carrier subassembly comprising a tubular carrier slidably arranged inside the case, where the carrier adapted to contain a syringe with a hollow injection needle. The injector also has, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for advancing the needle beyond a proximal end of the auto-injector, and a trigger button is used for releasing the control spring on actuation.

An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.