The invention of the present disclosure relates to a medicament dispenser for dispensing medicament from a plurality of elongate form medicament carriers, the dispenser comprising a dispensing mechanism for dispensing the medicament held within the dispenser, wherein the dispensing mechanism is capable of independently advancing each medicament carrier held within the dispenser, the dispensing mechanism comprising a driver, a carrier engagement for each medicament carrier for individually advancing the medicament dose portions thereof, an advancer for each carrier engagement, a flow director capable of dispensing a medicament dose from a plurality of medicament carriers, and a cover for the medicament access body operating as a component of the dispenser actuation mechanism.

The present disclosure provides a nasal delivery device with a device body that includes a trigger end and an outlet end. The nasal delivery device also includes a trigger assembly coupled to the trigger end of the device body, a drug container supported by the device body, and a spring-loaded activator assembly supported by the device body and disposed between the trigger assembly and the drug container.

A method of treatment for mixed carbon dioxide, carbonic acid, saline and optional active additives for treating non-nasal ailments includes delivery of dosage of the treatment at specified flow rates, using a) main housing having a hollow central area containing the dosage; b) a dosage dispenser head located at the distal end of the main housing, and having at least one flow channel for movement of the dosage from the main housing through the dosage dispenser head and to external of the dosage dispenser head; c) a dosage release control component located between the main housing and the dosage dispenser head to permit flow of the dosage through the dosage dispenser head in response to increased pressure against the dosage; and d) a pressure-changing moveable component on the main housing.

A pulmonary delivery system includes an elongated body having an openable and closeable portion thereof for receiving an insertable and replaceable container such as a cartridge of pure medical product disposed in a saline solution. The medical product may be epinephrine, insulin or nicotine disposed in a saline solution. The system also incorporates a penetrating element that is disposed in the cylinder to pierce the cartridge and release the nicotine solution into the cylinder and into or on a micron mesh grid. A flow of air created by inhaling through a mouthpiece draws air into an individual's lungs from an entrainment port and onto a grid for atomizing a mist of micron droplets through the grid. It is recognized that the air from the entrainment port further dilutes the concentration of the medical product. The grid is connected to a source of electrical power to vibrate the mesh grid.

A battery-operated foam inhalation device which comprises a cartridge (610) having a liquid for producing a foam and a foam outlet (654). Agitation means agitates the liquid to produce the foam, and the agitation means comprises an electric motor (762) and a battery (760) for energising the electric motor (762). A carrier (672) receives the cartridge (610) and has a carrier foam inlet (680) for fluid communication with the foam outlet (654) of the cartridge (610). A carrier foam outlet (682) dispenses the foam to a user.

The invention provides an apparatus for use in aerosolized delivery of a powder, and comprises a first chamber containing gas at a first pressure higher than atmospheric pressure, and a second chamber containing gas at a second pressure higher than atmospheric pressure. The apparatus also comprises a powder, contained within the first or second chamber. The first chamber has a first external wall and a separating wall, the separating wall being shared with the second chamber. The first external wall or the separating wall is configured to rupture if the pressure difference across it becomes equal to or greater than a threshold pressure difference. In particular, the apparatus is configured so that the difference between the second pressure and atmospheric pressure is greater than the threshold pressure difference. In an initial state, the apparatus is configured such that the difference between the second pressure and the first pressure is less than the pressure difference required to rupture the separating wall, and the difference between the first pressure and atmospheric pressure is less than the pressure difference required to rupture the first external wall.

A dry powder inhaler with a blister folding device can include a housing to receive a single blister containing a dose of medicament for inhalation by a user, and a mouthpiece through which a dose of medicament is inhaled by a user and a blister opening device. The blister opening device can include a blister support element for supporting a blister containing a dose of medicament for inhalation by a user, and a blister folding element co-operable with the blister support element. The blister folding element and the blister support element can be movable relative to each other between a first position, for insertion of the blister into or onto the blister support element, and a second, burst, position in which the blister folding element has co-operated with the blister support element.

A delivery device for use in administering a dry powder to a biological subject's airway is provided. The device comprises (a) a housing having an inlet in fluid communication with an outlet for delivering a flow of gas to the subject's airway; and (b) one or more cantilever structures located within the housing. Vibration of the one or more cantilever structures facilitates entry of the dry powder into the flow of gas, such that the dry powder can be delivered by the flow of gas through the outlet to the subject's airway. Also provided is a container for releasably storing a particulate composition, the container comprising a shell sealed by a seal in which the particulate composition is stored, wherein a puncturing device for rupturing the seal to release the particulate composition is housed within the shell. Further provided are associated methods for administering dry powder using the delivery device and/or container.

The present disclosure relates to a cartridge for use in an aerosol delivery device and an aerosol delivery device having the same. The cartridge includes a first reservoir configured to contain an aerosol precursor composition, and an atomizer having a liquid transport element in fluid communication with the first reservoir and a heating element configured to vaporize the aerosol precursor composition transported by the liquid transport element. The cartridge also includes a second reservoir, the second reservoir including two or more separate chambers, wherein at least one of the chambers contains a flavorant. A flow of air is configured to pass adjacent to the atomizer to entrain particles of the aerosol precursor composition that are vaporized by the heating element. The flow of air is also configured to pass at least one of the chambers of the second reservoir to entrain the flavorant of the respective chamber.

A stable-foam inhalation-device cartridge for a stable-foam inhalation device which dispenses a stable foam to be consumed by a user. The cartridge is devoid of an electrical energisation component. The cartridge includes a flexible mixing chamber, first and second foam-generation elements, an expansion chamber, a partitioning element having one or more mixing members for agitating a consumable foam and a discharge element. The discharge element has an outlet opening an inlet opening and a discharge conduit which interconnects the inlet opening with the outlet opening. The discharge conduit has a longitudinal extent which locates the inlet opening at a position closer to the partitioning element than to the outlet opening.