A package including a body portion, a sealing portion, and a combustible plant-based material is disclosed. The body portion can include a combustible or burnable material.

A delivery device for delivering a metered amount of substance (L) in response to exhalation by a user, the delivery device comprising: a mouthpiece (5) through which the user in use exhales; an outlet (45) from which substance Is delivered; and a dispensing unit (35) which is operable to dispense a metered amount of substance through the outlet in response to exhalation by the user through the mouthpiece, wherein the dispensing unit comprises a body member (37) which includes a cavity (39) for containing a metered amount of substance, an outlet nozzle (43) which is fluidly connected to the cavity from which substance is in use delivered, and a dispensing (41) member which is movably disposed in the cavity and configured to be driven through the cavity by a driving pressure created by exhalation of the user, such as to cause substance to be delivered from the outlet nozzle.

The present disclosure relates to a nebulization composition comprising tiotropium and formoterol for the treatment of inflammatory or obstructive airway disease. The present disclosure also relates to a process for preparing the composition.

A delivery device for use in administering a dry powder to a biological subject's airway is provided. The device comprises (a) a housing having an inlet in fluid communication with an outlet for delivering a flow of gas to the subject's airway; and (b) one or more cantilever structures located within the housing. Vibration of the one or more cantilever structures facilitates entry of the dry powder into the flow of gas, such that the dry powder can be delivered by the flow of gas through the outlet to the subject's airway. Also provided is a container for releasably storing a particulate composition, the container comprising a shell sealed by a seal in which the particulate composition is stored, wherein a puncturing device for rupturing the seal to release the particulate composition is housed within the shell. Further provided are associated methods for administering dry powder using the delivery device and/or container.

The present invention relates to a preparation for inhalation use in form of dry powder comprising particles of ambroxol and/or hydrochlorides thereof, and at least a pharmaceutically acceptable excipient and/or dispersant wherein at least 85% of said particles has a geometrical diameter from 3 to 5 m. The present invention further relates to the methods for preparing such composition and uses thereof. The present invention thanks to the very fine particles of dry powder, as above defined, constitutes a composition for inhalation use with optimum performances which, combined with inhaler action, reaches and acts directly on the bronchi or on the damaged respiratory tract. The local action and the quick absorption of the drug guarantee good features of bioavailability. The decrease in dosing Ambroxol with respect to the other existing oral or injectable formulations allows to reach quickly, locally and safely, the therapeutic target.

A nebulizer unit includes a housing, which includes an aerosol generator with a feed chamber disposed at one side, an ampoule receiver, an opening device with at least one opening, which is in communication with the feed chamber, and an ampoule with liquid, which comprises at least one opening, with which it can be inserted or used in the ampoule receiver, wherein the ampoule has a connection region, which interacts with a connector of the ampoule receptacle in order to hold the ampoule firmly in the ampoule receiver and to connect the openings such that they are leak tight.

Various exemplary drug delivery devices with propellant, drug products utilizing the same, and methods of using drug delivery devices with propellant are provided. In general, a nasal drug delivery device is configured to expel a drug into a nose of a patient and to drive delivery of the drug using a propellant. The propellant includes a gas, e.g., air, carbon dioxide, etc., and/or at least one material substance configured to produce energy that causes movement of the drug out of an opening of the drug delivery device.

The e-vaping device includes a first housing, a chamber defined within the first housing, a first structure and a second structure that interface with the chamber, the first structure is configured to accept at least one first-type consumable within the chamber and the second structure is configured to receive at least one second-type consumable within the chamber.

The method includes defining a chamber withing a first housing, the chamber including a first-shaped cavity and a second-shaped cavity configured to receive a first-type consumable and a second-type consumable, respectively.

The present disclosure relates to a cartridge for use in an aerosol delivery device and an aerosol delivery device having the same. The cartridge includes a first reservoir configured to contain an aerosol precursor composition, and an atomizer having a liquid transport element in fluid communication with the first reservoir and a heating element configured to vaporize the aerosol precursor composition transported by the liquid transport element. The cartridge also includes a second reservoir, the second reservoir including two or more separate chambers, wherein at least one of the chambers contains a flavorant. A flow of air is configured to pass adjacent to the atomizer to entrain particles of the aerosol precursor composition that are vaporized by the heating element. The flow of air is also configured to pass at least one of the chambers of the second reservoir to entrain the flavorant of the respective chamber.