Patent classifications
A61M15/0043
CAPSULE INHALERS AND METHODS OF USING SAME
The present disclosure describes a capsule inhaler. The capsule inhaler includes a main body including an inner cavity, a mouth section coupled to or integral with the main body and in fluid communication with the inner cavity, an actuator coupled to the main body, at least four longitudinally spaced apart nozzles residing within the main body positioned and configured to direct airflow into the inner cavity, and a cover coupled to the main body. The inner cavity is sized and configured to receive a capsule containing a dry powder formulation. One or more of the inner cavity, elongate member, and cover each are configured to engage with the capsule when inserted into the inner cavity and assist in separating the capsule to release the dry powder formulation into the inner cavity of the inhaler for inhalation by a subject. At least two of the nozzles are positioned and configured to direct airflow received from the at least one air intake port into separated segments of the capsule and at least another two of the nozzles are positioned and configured to direct bypass airflow received from the at least one air intake port into the inner cavity. Methods of using a capsule inhaler are also described herein.
System composed of inhaler and capsule
The invention relates to a system composed of an inhaler and a capsule, preferably intended for single use. The capsule contains a preferably powdered pharmaceutical preparation which, for inhalation, is expelled from the capsule through at least one hole. The capsule comprises as capsule elements a capsule cap and a capsule body, at least one of which comprises at least one prefabricated hole. The prefabricated hole in the capsule is sealed off in the transporting state of the system and is open in the usage state. The hole is exposed by actuation of a pulling mechanism. Prior to this the hole is closed off by a capsule receptacle or a film. In one embodiment the capsule may be present in two different states, for example in different insertion positions of the capsule elements. In the first state the prefabricated hole is closed off and in the second it is exposed. Also shown is an inhaler suitable as a disposable product, which is manufactured from thermoformed parts or from blister film.
Powder inhaler and powder inhalation set
The invention relates to a powder inhaler and to a powder inhaler set that contains the powder inhaler. The powder inhaler comprises two half-shells (3, 4), which are connected to each other by means of at least one film hinge and are formed as a single piece. In a joined arrangement, the two half-shells (3, 4) enclose an air inlet region, a powder deposition region and powder release region, and an outlet region, through which regions a fluid path extends, wherein at least one of the half-shells (3, 4) has at least one air inlet opening (8) in the air inlet region. Furthermore, one of the half-shells (3, 4) has at least one powder-accommodating recess (9) in the powder deposition region and powder release region, while the outlet region has at least one deagglomeration structure (17, 17) and an outlet for aerosol, which outlet is formed by the half-shells (3, 4).
DRY POWDER INHALATION DEVICE
Taught herein is a disposable breath actuated dry powder drug inhalation device having a powderized drug storage chamber with integral toroidal geometry and air flow pathways for entraining and breaking up powder aggregates prior to delivery to the patient. The toroidal chamber is fluidly connected by one or more air inlets directed in a non-tangent manner toward the powder to loft and set up an irregular-rotational flow pattern. Also, in fluid connection with the toroidal chamber is a centrally or near centrally located air and powder outlet consisting of one or more holes forming a grid in fluid connection with a channel providing a passageway for powder flow to the patient.
NASAL DELIVERY DEVICE FOR A POWDER
A nasal powder dispenser device having a reservoir containing at least one dose of powder; a nasal dispenser head for inserting into a user's nostril, the nasal dispenser head including a dispenser orifice; and an air expeller that, during actuation of the nasal powder dispenser device, generates a flow of compressed air so as to dispense a dose of powder into the nostril through the dispenser orifice. The air expeller has an air chamber and a piston that slides in airtight manner in the air chamber so as to compress the air contained in the air chamber. In the nasal powder dispenser device, a pressure of the flow of compressed air generated by the air expeller is higher than 0.7 bar; and a volume of the air chamber is greater than 1700 mm.sup.3.
Powder compartment for high dosage drug delivery
A dry powder inhaler for pulmonary or nasal use, comprising at least an inhaler body 801 and a cartridge 803 with at least one powder compartment 805 including one dose of a drug. The body has an opening 804 shaped for receiving the cartridge 803 and the means to allow a controlled sliding movement of the cartridge 803 relative to the body 801 after mounting. The cartridge powder compartment 805 comprises at least two inlets or slits 806, 809, at least one of which is a side inlet 809, for the admission of air, and a compartment outlet 807 to allow filling and fluid communication with an inhalation channel 808 provided in the body 801. In use, the patient slides the cartridge 803 relative to the body 801 from the storage position, where the inlets in the cartridge powder compartment 805 are blocked and sealed by walls comprised in the body 801, into the inhalation position, where the compartment inlets become available for the admission of air used in the dispersion of the particles there contained and the compartment outlet 807 becomes aligned with the inhalation channel 808 in the body 801 to allow the entrainment of the dose dispersed through the device and into the desired site of action during inhalation. The addition of one or more lateral vents 809 in the cartridge powder compartments induces a turbulent and swirling flow pattern that promotes improved dispersion and entrainment. The invention affords a very economical and simple device for the delivery of high dosages of inhaled medicines.
Methods and apparatus for producing herbal vapor
The present disclosure relates to systems and methods for producing a consistent and effective herbal vapor. A sealed container pod may include a chamber wall defining an internal volume within which a pre-processed herbal composition (e.g., cannabis) is located. The container pod may include filters for the vapor produced from the herbal composition. The container pod may also include a support member for holding and evenly distributing the herbal composition within the internal volume during vaporization. A vaporizer may be configured to obtain information regarding the contents of the herbal composition. The vaporizer may expose the herbal composition to an automated series of timed temperature adjustments specifically tailored for producing a desirable herbal vapor. The herbal vapor may be collected into a bag and/or canister for subsequent consumption.
Device for dispensing a fluid product
Device for dispensing a fluid product having a body (1) and dispensing head (2) provided with a dispensing opening (3) and axially movable with respect to the body (1) during actuation. The body (1) accommodates a reservoir (10) containing one or two doses of fluid product. The device has an electronic module (100) with a wireless communication module (101), a geographical location module (102), and a power source (103). The device has a system of sensors (200, 201, 202) for detecting and signaling, automatically, an attempt to actuate the device, when a first sensor (200) is activated. The wireless communication module (101) is adapted to make an automatic emergency call to an emergency number when the sensor system detects an attempt to actuate the. The first sensor is activated when it detects an actuation force greater than 5N or 10N.
Devices and methods for delivering dry powder medicaments
An apparatus includes a first member coupled to a second member. The first member defines a chamber containing a dry powder and includes a chamber wall that forms an outer boundary of the chamber. The second member includes a surface covering the chamber and defines an intake channel and an exit channel. The exit channel is fluidically coupled to the chamber via an exit opening. The intake channel is fluidically coupled to the chamber via an intake port. A center line of the intake channel is tangential to a portion of the chamber wall such that a portion of an inlet airflow conveyed into the chamber via the intake channel has a rotational motion. The intake port is defined at least in part by an intake ramp. The intake ramp includes a transition surface that forms an exit angle with respect to the surface of less than 105 degrees.
Powder inhaler and powder inhalation set
The invention relates to a powder inhaler and to a powder inhaler set that contains the powder inhaler. The powder inhaler comprises two half-shells (3, 4), which can be or are articulated to each other and which enclose an air inlet region, a powder deposition region and powder release region, and an outlet region in a joined arrangement, through which regions a fluid path extends. At least one of the half shells (3, 4) has at least one air inlet opening (8) in the air inlet region, and at least one air-swirling structure (5) is present in the air inlet region, which air-swirling structure defines the fluid path between the at least one air inlet opening (8) and the powder deposition and release region. Furthermore, one of the half-shells (3, 4) has at least one powder-accommodating recess (9) in the powder deposition region and powder release region, while the outlet region has at least one deagglomeration structure (17, 17) and an outlet for aerosol, which outlet is formed by the half-shells (3, 4).