Some embodiments are directed to an adherence monitor for use with a tethered cap inhaler device. The monitor engages the inhaler device, and includes a tether opening for receiving the tether, so that the path length of the tether around the monitor is minimized or reduced.

An inhaler includes a main body having a canister housing, a medicament canister retained in a central outlet port of the canister housing, and a dose counter having an actuation member for operation by movement of the medicament canister. The canister housing has an inner wall, and a first inner wall canister support formation extending inwardly from a main surface of the inner wall. The canister housing has a longitudinal axis X which passes through the center of the central outlet port. The first inner wall canister support formation, the actuation member, and the central outlet port lie in a common plane coincident with the longitudinal axis X such that the first inner wall canister support formation protects against unwanted actuation of the dose counter by reducing rocking of the medicament canister relative to the main body of the inhaler.

A fluid dispenser device having at least one reservoir (20) that is suitable for containing fluid to be dispensed and a propellant gas; a valve (30), in particular a metering valve, that is mounted on said reservoir (20); and a body (10) including a dispenser orifice (40) via which the fluid is dispensed. The reservoir (20) is movable in the body (10) so as to actuate the valve (30); at least a portion of the dispenser device is made out of a material having an aliphatic polyketone.

The present invention discloses a liquid, propellant-free pharmaceutical formulation and a method for administering a pharmaceutical preparation by nebulizing the pharmaceutical preparation in an inhaler. The propellant-free pharmaceutical formulation comprising: (a) active substances selected from aclidinium bromide and formoterol fumarate; (b) a solvent; and (c) a pharmacologically acceptable preservative, optionally including a pharmacologically acceptable stabilizer, a pharmacologically acceptable solubilizing agent, or other pharmacologically acceptable additives.

A system may include an external device and an inhaler. The external device may include a processor, a communication circuit, and memory. The inhaler may include a mouthpiece, medicament, a mechanical dose counter, and an electronics module comprising a processor and a communication circuit. The electronics module may record a dosing event when the inhaler is actuated, such as when the mouthpiece cover is opened, and send a signal indicating the dosing event to the external device. The external device may receive a mechanical dose reading of the mechanical dose counter, determine an electronic dose reading based on the signal indicating the dosing event, determine that a discrepancy between the mechanical dose reading and the electronic dose reading exceeds a threshold, and notify the user of the discrepancy, for example, by providing a notification to the user by way of a mobile application residing on the external device.

Embodiments relate to an intranasal drug delivery device, system, and process. The drug delivery device can have a compliant/flexible soft nib. The drug delivery device can have an actuator and shot chamber. The drug delivery device can have a non-air interface mechanically pressurized fluid reservoir. The drug delivery device can have a facial or device recognition application to prevent intentional or unintentional misuse.

A fluid dispenser device having at least one reservoir (20) that is suitable for containing fluid to be dispensed, a dispenser member (1, 30), an actuator member (2, 10) that is suitable for actuating said dispenser member (1, 30); a dispenser orifice (3, 40) via which the fluid is dispensed; and a dose counter or indicator (A). At least a portion of the dose counter or indicator (A) is made out of a material having an aliphatic polyketone.

The present disclosure relates to systems, methods, and devices that may be used to incentivize inhaler use.

A device (20) is disclosed for dispensing a fluid supplied from an external fluid source. The device comprises a transducer (32) adapted to receive a fluid from the fluid source, and a collapsible linkage and trip link (502) coupling the transducer and the fluid source. The linkage has a collapsible joint inhibiting discharge of the fluid source when in a locked orientation. The device (20) further comprises a moveable member coupled to the linkage such that inhalation forces on the device cause the linkage to collapse thereby discharging the fluid from the fluid source. The device may further include a dose counter coupled to the fluid source for registering the amount of doses administered from the fluid source.

A metered dose inhaler (1) for dispensing aerosol doses comprises an actuation housing (2) adapted to receive a canister (4). The canister (4) is configured to move from a rest position to an activation position in which a valve (7) of the canister (4), positioned at a valve end (8) of the canister (4), is depressed against a bottom portion of the actuation housing such that an aerosol dose is released. The inhaler (1) further comprises a mechanical dose (10) counter comprising an indicator member which is constructed and arrangement to undergo a predetermined count-indicating motion when an aerosol dose is released. Moreover, the inhaler (1) comprises a triggering unit (11) for triggering at least one electrical switch (12) when the canister (4) is moved from the rest position to the activation position whereby an electrical signal is generated. Also part of the inhaler (1) is a processing unit for processing the signal generated by the switch (12) upon being triggered.