An apparatus includes an outer portion comprising a primary opening, a first pillar support and a second pillar support coupled to the outer portion, a first upper gum support rotatably coupled to the first pillar, a first lower gum support rotatably coupled to the first pillar, a second upper gum support rotatably coupled to the second pillar, a second lower gum support rotatably coupled to the second pillar, a first upper gum end rotatably coupled to the first upper gum support, a first lower gum end rotatably coupled to the first lower gum support, a second upper gum end rotatably coupled to the second upper gum support, and a second lower gum end rotatably coupled to the second lower gum support.

A high flow therapy system for delivering heated and humidified respiratory gas to an airway of a patient, the system including a respiratory gas flow pathway for delivering the respiratory gas to the airway of the patient by way of a non-sealing respiratory interface; wherein flow rate of the pressurized respiratory gas is controlled by a microprocessor.

The present invention relates to an exhalation disposal system for collecting, transporting and properly disposing of a bio-waste exhalation from an infectious patient in a closed system, thereby minimizing, if not completely eliminating, contact between medical personnel and the infectious patient's bio-waste exhalation. The system utilizes a length of flexible vacuum tubing in communication with both a specialized patient mouthpiece and a waste drain, and a check valve positioned along the length of the tubing to prevent backflow of the bio-waste exhalation. In an exemplary embodiment, the disposal system further comprises at least one sensor, a window and an access point for clearing blockages that may arise in the disposal system during use. The disposal system is configured to service multiple infectious patients simultaneously.

A gas delivery conduit adapted for fluidly connecting to a respiratory gases delivery system in a high flow therapy system, the gas delivery conduit includes a first connector adapted for connecting to the respiratory gases delivery system, a second connector adapted for connecting to a fitting of a patient interface, tubing fluidly connecting the first connector to the second connector where the first connector has a gas inlet adapted to receive the supplied respiratory gas, one of electrical contacts and temperature contacts integrated into the first connector. The gas delivery conduit further can include a sensing conduit integrated into the gas delivery conduit, where the first connector of the gas delivery conduit is adapted to allow the user to couple the first connector with the respiratory gases delivery system in a single motion.

A gas delivery conduit adapted for fluidly connecting to a respiratory gases delivery system in a high flow therapy system, the gas delivery conduit includes a first connector adapted for connecting to the respiratory gases delivery system, a second connector adapted for connecting to a fitting of a patient interface, tubing fluidly connecting the first connector to the second connector where the first connector has a gas inlet adapted to receive the supplied respiratory gas, one of electrical contacts and temperature contacts integrated into the first connector. The gas delivery conduit further can include a sensing conduit integrated into the gas delivery conduit, where the first connector of the gas delivery conduit is adapted to allow the user to couple the first connector with the respiratory gases delivery system in a single motion.

A noninvasive, brain cooling method and device for cerebral cooling via a patient's nasopharyngeal cavity, is described. Thermal conductive nasal prongs are inserted into a nasal cavity and are cooled by thermoelectric cooling elements. An outward air driving fan inside the device drives a cold air current through the nasal and oral cavities. Heat transfer between the cold air and the surface of the nasal cavity cools the nasal cavity, which in turn, cools a patient's brain. Real-time temperature sensing data provides feedback for closed-loop cooling control.

A pediatric nebulizer assembly includes an oxygen hose and a nebulizer containing a fluid medication. The nebulizer engages the oxygen hose to nebulize the fluid medication into oxygen for delivering outwardly through the outlet. A tee fitting releasably engages the nebulizer to receive the nebulized fluid medication and the oxygen. A mouthpiece is attachable to the tee fitting to receive the nebulized fluid medication and the oxygen for inhalation by a patient. A rifled barrel is attachable to the elbow fitting when the mouthpiece is not attached to the tee fitting to receive the nebulized fluid medication and the oxygen. In this way the rifled barrel enhances delivery to a pediatric patient that may be not be capable of inhaling through the mouthpiece.

Provided herein are methods of treatment, including methods of treating subjects having or at risk of having or having a viral infection, and specifically a SARS-CoV-2 viral infection. The methods provided include the administration of 4-methylumbelliferone (4-MU), palmitoylethanolamide (PEA), reservatrol, fisetin, H.sub.2, nebulized hyaluronidase or combinations thereof. Also provided herein are a respiratory assistance device, methods of generating a customized respiratory assistance device, methods of treating a coronavirus infection, and methods of inhibiting a coronavirus infectivity, virulence and/or spread.

A therapy system configured to wash out or flush out the oral and/or nasal cavity to reduce the effective dead space and reduce the work of breathing. The system may displace the expired air in the oral and/or nasal cavity with atmospheric air, or air with altered concentrations, for example, increased humidity, or oxygen levels. A sealed oral interface is provided to the mouth of a patient to supply a volume of pressurized gas. A control system to synchronize the supply of pressurized gas with the patients respiratory cycle. The supply of respiratory gas may be provided during only a portion of the respiratory cycle.

Disclosed embodiments of an endotracheal tube (ETT) guard system help to hinder self-extubation of the ETT of an awake patient who may reflexively attempt removal, but also allow early mobilization and exercise necessary for preservation of muscle strength. Embodiments may include an ETT holder, which may be generic ETT holders offered by various medical device companies, or a specially configured ETT holder as described herein. Embodiments also may include a sensor that alarms when the ETT guard is moved beyond pre-set motion thresholds.