A respiratory therapy system can have a flow generator adapted to provide gases to a patient. A gas passageway can be located in-line with the flow generator. The gas passageway can have a first portion adapted to receive a first gas and a second portion adapted to receive a second gas. The gas passageway can have a static mixer downstream of the first and second portions.

A ventilator includes a ventilation body, the ventilation body includes a ventilation cavity and an air inlet end and an air outlet end communicating with the ventilation cavity, the ventilation body further includes an annular shell configured to form the ventilation cavity, the annular shell is formed with an annular cavity inside, an air inlet and an air outlet communicating with the annular cavity are disposed on the annular shell, the air outlet is communicated with the annular cavity and the ventilation cavity, the air outlet has a slit shape extending along a circumferential direction of the annular shell and is disposed to be capable to guide gas flows out towards the air outlet end. The ventilator may greatly increase the ventilation volume and the gas pressure, by using the ventilation body as mentioned above.

A system for delivering a therapeutic amount of nitric oxide can include a reservoir containing a nitrogen dioxide source. A heating element can be configured to heat the reservoir, causing nitrogen dioxide vapor to exit the reservoir through a restrictor into a conduit. The nitrogen dioxide vapor can mix with gas from a gas supply, which can then flow to a cartridge that includes a surface-activated material saturated with an aqueous solution of a reducing agent. The cartridge can convert the nitrogen dioxide into nitric oxide.

Various systems, devices, NO.sub.2 absorbents, NO.sub.2 scavengers and NO.sub.2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.

Various embodiments are described herein for a controller for controlling the operation of a breathing assistance device that provides breathing assistance to a user. The controller comprises a processor that generates a respiratory index value that is determined during a current monitoring time period to detect a respiratory failure, or predict the respiratory failure when at least one PSG signal is measured. The respiratory index value is compared to a threshold to determine if the control signal needs to be updated to reduce or eliminate respiratory failure that the user is currently experiencing or to prevent a predicted respiratory failure from occurring.

A trap bowl is provided to accumulate liquid droplets from a filter, as a liquid content. The trap bowl includes a transparent vertical prism, The transparent vertical prism includes a face that forms a vertical transparent surface facing against a content of the section, The face can provide a first angle of total reflection when content of the section is a type of gas, and a second angle of total reflection when the content of the section is the liquid content. A light source may emit a light beam incident on the face at an angle of incidence. The angle of incidence results in reflection of the light beam, striking the light receiver, when the face has the first angle of total reflection, and results in refraction of the light beam, missing the light receiver, when the face has the second angle of total reflection.

The principles and embodiments of the present invention relate to methods and systems for safely providing NO to a recipient for inhalation therapy. There are many potential safety issues that may arise from using a reactor cartridge that converts NO.sub.2 to NO, including exhaustion of consumable reactants of the cartridge reactor. Accordingly, various embodiments of the present invention provide systems and methods of determining the remaining useful life of a NO.sub.2-to-NO reactor cartridge and/or a breakthrough of NO.sub.2, and providing an indication of the remaining useful life and/or breakthrough.

An apparatus for delivery of a flow of gases to a user, such as a respiratory therapy apparatus, is provided. The apparatus may have first and second inlets for receiving supplementary gases flows, a blower to generate the gases flow to the user, and a controller. A valve and a sensor may be provided in the second inlet. The controller may be configured to detect the disconnection of a gases source from the second inlet, and to respond by operating the valve and/or triggering an alarm. The controller may be configured to determine whether a gases flow is being provided at one or both of the inlets, and to accordingly control an operational mode of the apparatus.

A system for sterilization of a medical device comprising at least one medical device and at least one sterilization device. The sterilization device comprises at least one plasma generator and at least one water source and/or water vapor source for providing water and/or water vapor. The sterilization device is configured to generate plasma-activated water vapor and the system is configured to at least partially conduct the plasma-activated water vapor through the medical device.

An apparatus, method and system for delivering CO.sub.2 into an inspiratory gas stream to formulate a blended respiratory gas in a manner that continuously maintains a target CO.sub.2 concentration in a volume of the inspired respiratory gas, for example, over the course of a breath or a volumetrically definable part thereof or a series of partial or full breaths.