An apparatus used to disinfect viruses/bacteria contaminated exhaust air from devices, such as ventilators, CPAP, APAP, VPAP auto, BiPAO, ECMO, and also devices for air filtration used in cars, buildings, ships, planes, etc. is disclosed in this document. A heat source is used to burn the contaminated air at elevated temperatures, such as 100° C., 500° C., 1,000° C., and/or even more, in a confined environment to inactivate/destroy viruses/bacteria carried in the air. The heat sources can be, but not limited to, electrical, gases, infrared, microwave, and Ultraviolet (UV). After disinfection, the exhaust air from the apparatus is then released to the ambient environment, or to the next chamber for further treatment.

The present disclosure provides methods of treatment of COVID-19 through pH modulation of the respiratory tract using a controlled delivery device. In some embodiments, the controlled delivery device includes an aerosolizer, a microprocessor, and a syringe. The controlled delivery device can be integrated with a humidifier or a ventilator. In some embodiments, two agents are delivered in conjunction using the controlled delivery device. In some embodiments, one agent is a physiologically compatible alkalizing agent, such as an aqueous solution of sodium bicarbonate of strength 3%-8.4% at a pH ranging from 8 to 8.6 at 20° C. In some embodiments, one agent is an anti-inflammatory agent, such as corticosteroid ciclesonide.

A thermogenic emergency airway management device configured to prevent or treat hypothermia in a patient. The device may be configured to receive inlet air and modify one or more properties of the inlet air to output air at a temperature and/or humidity associated with the prevention and/or treatment of hypothermia. In an embodiment, the device may receive input via a user interface to determine a temperature and/or humidity associated with the air to be output to the patient. In an embodiment, the input may additionally include an amount of air to be output to the patient. In such an embodiment, the device may be configured to cause the amount of air to be output to the patient to prevent and/or treat hypothermia.

A ventilation control unit (100), regulating a gas flow (102) within a ventilation system (105), includes a reception module (120), first and second calculation modules (130, 135) and an output module (140). The reception module has a signal interface (122) receiving inspiratory and expiratory flow signals (125, 127) at regular time intervals. The first calculation module calculates a leak flow (132) based on a difference between the current inspiratory gas flow and the current expiratory gas flow, with an external gas flow source (110) separated from a ventilation circuit of the ventilation system. The second calculation module calculates an external gas flow (136) after connecting the external gas flow source to the ventilation circuit based on the leak flow and the difference between the current inspiratory gas flow and the current expiratory gas flow. The output module outputs an output signal (142), based on the external gas flow.

The disclosure relates to a nasal cannula comprising a port configured for delivery of a medicament into a flow of a fluid being delivered by the nasal cannula to a user and/or configured for interfacing with a medicament delivery device or an instrument. The disclosure also relates to a nasal cannula comprising an asymmetric profile to reduce an amount of occlusion of one nare of a user to provide access for an instrument to the nare with the nasal cannula in use.

A supplemental oxygen delivery system is described in which Aerosol is delivered into a housing 10, 20, which sits in the circuit from the supplemental oxygen supply and optional humidifier. The supplemental oxygen passes through this chamber 10, 20 in which the aerosol is located, and collects the aerosol transporting it to a patient via a nasal cannula 3 or a face mask 4. An aerosol generator 9 is mounted to the housing 10, 20 and delivers aerosol into an oxygen stream 13 flowing between an inlet 14 and an outlet 15 of the housing 10. The housing 10 also has a removable plug 16 in the base 17 thereof for draining any liquid that accumulates in the housing 10. There is no disruption of oxygen delivery to patients using nasal cannulas who currently have to use a separate face-mask when receiving nebulized medication.

An adaptor for a respiratory assistance system delivers aerosols to a patient. The adaptor is lightweight with a small footprint to increase patient comfort. The adaptor has a nozzle and a sealing mechanism to maintain pressure therein regardless of whether the nozzle is inserted into the adaptor. The adaptor is configured to connect to medical tubing and a medicament delivery device.

The disclosure relates to a nasal cannula comprising a port configured for delivery of a medicament into a flow of a fluid being delivered by the nasal cannula to a user and/or configured for interfacing with a medicament delivery device or an instrument. The disclosure also relates to a nasal cannula comprising an asymmetric profile to reduce an amount of occlusion of one nare of a user to provide access for an instrument to the nare with the nasal cannula in use.

The present invention discloses a device for removing sputum scabs of a respiratory tract, comprising an outer housing. A fluid hole is designed on a removing part at the front end of the outer housing, and the fluid hole is respectively communicated with a liquid pump and an air pump, so that the device can be extended into the lower respiratory tract of the patient during use. Then, the sputum scabs attached to the inner wall of the respiratory tract can be softened and removed by alternately spraying liquid and gas from the fluid hole, and the removed sputum scabs can be sucked out through negative pressure holes, so as to prevent the scabs of the secretions of the lower respiratory tract from blocking the tracheae.

Substance supply apparatus, systems and methods are provided herein. In some aspects, a substance supply apparatus comprises a tank assembly coupled to a manifold. The tank assembly can comprise a cavity housing one or more electrical components, a set of heating elements electrically coupled to the electrical components, and wherein each heating element is configured to couple with a cartridge configured to house a substance to be heated. The manifold can comprise a plurality of delivery ports, wherein each delivery port is configured to couple with a cartridge that is also coupled to the heating element. In some aspects, a system comprises one or more supply apparatus, as well as one or more inhalation chambers, actuator devices, supply paths from the apparatus to an inlet port of the chambers, and one or more controllers.