Disclosed herein are methods, systems, and devices for controlling a gas mixture within a mechanical ventilator. According to one embodiment, a computer implemented method includes receiving first peripheral arterial oxygen saturation (SpO.sub.2) data from a pulse oximeter via a pulse oximeter interface, wherein the pulse oximeter is configured to monitor a patient receiving invasive ventilation; determining a first mode of operation for a ventilator mechanism, wherein the ventilator mechanism is configured to provide at least a portion of the invasive ventilation; determining first partial pressure of oxygen (PaO.sub.2) data stored in a first lookup table using the first SpO.sub.2 data, wherein the first lookup table is derived from a sigmoid shaped oxyhemoglobin dissociation curve; determining first fraction of inspired oxygen in air (FiO.sub.2) data for setting a mixture in a gas blender in the ventilator mechanism based on the first PaO.sub.2 data and a variable offset; and providing the FiO.sub.2 data to the ventilator mechanism.

Systems slow breathing with positive pressure therapy. In embodiments, a current interim breathing rate target is set, and periodically magnitude of a variable pressure waveform scaled to the current interim breathing rate target is increased if breathing rate is greater than the interim rate target to lengthen breath duration. The magnitude of the pressure increase may be a function of the difference between the interim rate target and the breathing rate. The interim rate target may be reduced in response to slowing breathing rate. The waveform cycles, inhalation to exhalation, when airflow decreases to a cycle threshold. Different interim rate targets have different cycle threshold functions that allow easier cycling as the interim rate targets decrease. Similarly, the waveform triggers, exhalation to inhalation, when airflow increases to a trigger threshold. Different interim rate targets have different trigger threshold functions that allow easier triggering as the interim rate targets decrease.

Product manifolds for use with portable oxygen concentrators and portable oxygen concentrators including such product manifolds. A product manifold for use with a portable oxygen concentrator includes a first product port, a second product port, an accumulator port, an output port, and a flow path. The flow path operatively coupling each of the first product port, the second product port, the accumulator port, and the output port to one another. The product manifold includes a plurality of control ports. Each of the control ports fluidly coupling the flow path. The product manifold includes a first orifice disposed in a first portion of the flow path; a second orifice disposed in a second portion of the flow path; and a third orifice disposed in a third portion of the flow path. Each of the first orifice, the second orifice, and the third orifice being formed by an electrical forming process and having a thickness of between about 0.0025 inches and about 0.004 inches.

A respiratory device can include an oxygen generator and a ventilator. The oxygen generator can include a first inlet to ambient air, a vacuum or pressure swing oxygen generating system in fluid communication with the first inlet, a first fluid pathway, and a first outlet. The ventilator can include a second inlet to ambient air and a blower in fluid communication with the second inlet to draw ambient air. The ventilator can include a third inlet in fluid communication with the first fluid pathway upstream of the first outlet. The blower can also be in fluid communication with the second inlet to draw at least some of the extracted oxygen. The ventilator can also include a second outlet in fluid communication with the blower to dispense a mixture of the ambient air and the extracted oxygen to the user.

A method of controlling a ventilation system includes displaying, on a display screen of a ventilation system, a first bar including a plurality of parameter segments. Each parameter segment indicates a level of a ventilation setting. The method further includes displaying, on the display screen, a second bar including a plurality of time segments. Each time segment indicates a time duration of a corresponding parameter segment of the first bar. As time passes, the display of the second bar is altered based on an amount of time passing. Upon a time duration of a time segment expiring, the ventilation setting is altered by the ventilation system to a level corresponding to a subsequent parameter segment. The display of the first bar is altered to highlight the subsequent parameter setting.

Described herein is a respiratory care apparatus capable of performing multitude of therapy for secretion management and breath assistance therapy. The respiratory care apparatus comprises an electromechanical air router assembly (EARA) and an interfacing assembly. The EARA includes independent first and second pressure generating sources for assisted inhalation/insufflation and assisted exhalation/exsufflation process. The interfacing assembly includes a patient interface port and a patient interface tube. The and negative pressure at the patient interface port for assisted inhalation/insufflation and assisted exhalation/exsufflation processes respectively. The assisted inhalation/insufflation and assisted exhalation/exsufflation processes are carried out independently through separate conduits/passages to reduce contamination and infection. Further, the respiratory care apparatus comprises a garment which oscillates due to alternate positive and negative pressure generation and provides therapy to the patient.

A patient support apparatus includes a bed including a frame. A mattress is supported by the frame. A respiratory therapy apparatus is supported by the frame. A pneumatic system is operable to inflate at least one bladder of the mattress and operable to deliver air to the respiratory therapy apparatus.

Sensing airflow and delivering therapeutic gas to a patient. At least one example embodiment is a method including: sensing, by a delivery device, that multiple breathing orifices are open to flow; and during a plurality of subsequent inhalations in which multiple breathing orifices are open to flow; and delivering, by the delivery device, a bolus of therapeutic gas to only one breathing orifice during each inhalation, and alternating delivery location in subsequent inhalations. The example delivering may further comprise: supplying therapeutic gas only from an accumulator during a first portion each inhalation; dispensing therapeutic gas from the accumulator and from a pressure regulator during a second portion of each inhalation, the second portion immediately subsequent to the first portion.

The present invention relates to an apparatus for providing respiratory assistance to a user via a user conduit. The apparatus being operable in a humidifying mode and a non-humidifying mode, and includes a humidification chamber for containing an amount of water that can be located in an operating position in the humidifying mode and, optionally separate from the apparatus in the non-humidifying mode. The apparatus may also have an auxiliary flow path that can be activated in the non-humidifying mode and a powered device that heats water in the humidification chamber when the apparatus is in the humidifying mode.

Methods and apparatus provide controlled operations in an oxygen concentrator (100) such as by adjusting valve opening time to regulate amount of oxygen enriched air released to a user. The apparatus may generate, with a sensor configured to sense pressure at a location associated with accumulation of enriched air produced by the concentrator, a signal representing measured pressure of the accumulated enriched air. The apparatus may generate, with a sensor, a signal indicative of respiration of a user of the concentrator. The apparatus may include a controller configured to receive the measured pressure and respiration signals. The controller may control, responsive to the respiration indication and according to a target duration, actuation of a valve adapted to release a bolus of accumulated oxygen enriched air. The controller may dynamically determine the target duration during the release of the bolus according to a function of a value of the measured pressure.