The present invention includes an apparatus and method for breaking up mucus in a lung comprising: a chamber having an inlet and an outlet; a pressure oscillating unit in fluid communication with the chamber for supplying and vacuuming air into/out of the chamber, wherein the pressure oscillating unit creates ultrasound waves; a control unit for selecting a positive air pressure or a negative air pressure from the pressure oscillating unit, a fluid container in fluid communication with the chamber; a pressure sensor in fluid communication with the chamber; and an outlet connected to the chamber to send respiration gas to a patient, ultrasonic waves in the respiration gas are capable of breaking up mucus in the lung.

A system for obtaining and providing enhanced PAP metrics of a patient's sleep period includes: a pressure support device for use in providing a flow of breathing gas to the patient; a processing unit; and a number of auxiliary devices in wireless communication with the processing unit. Each auxiliary device of the number of auxiliary devices is structured to detect and collect sleep-related data of the patient. The processing unit is programmed to: receive data obtained by a number of sensors of the pressure support device during operation of the pressure support device in providing the flow of breathing gas to the patient; receive supplemental data obtained by the number of auxiliary devices while the pressure support device is not providing the flow of breathing gas to the patient; and determine the enhanced PAP metrics of the sleep period of the patient utilizing the data and the supplemental data.

Systems and methods are provided for delivering one or more drugs. In some embodiments, a drug delivery system includes a housing having a distal end with an inlet through which an inspiratory flow of air passes into the housing, a proximal end having a patient interface attached thereto, the patient interface being configured to interface with a user, and an inspiratory flow pathway extending from the distal end to the proximal end of the housing. A nitric oxide (NO) source is positioned within the housing and is configured to deliver NO-containing gas to the patient interface. A secondary drug source is positioned within the housing and is configured to deliver a secondary drug to the patient interface. A controller is configured to control an amount of NO-containing gas and an amount of the secondary drug delivered using a control scheme.

A liquid ventilation system includes a reservoir holding a perfluorochemical (“PFC”) fluid, and a suction pump connected to the reservoir to reduce pressure within the reservoir. A sensor is configured to measure an intra-lung pressure. An appliance is configured to be disposed within a patient. The appliance carries an injector to supply the PFC fluid through the appliance. An extraction valve is disposed on an extraction line between the appliance and the reservoir. The extraction valve is arrangeable between a first position enabling fluid communication from the appliance to the reservoir and a second position disabling fluid communication from the appliance to the reservoir.

A respiratory delivery system providing a bi-level pressure airflow. The system includes respiratory and pneumatic circuits. The respiratory circuit includes a respiratory gas supply, a patient interface, and a bi-level pressure regulator. The respiratory gas supply supplies a respiratory gas to the patient interface via a first conduit. The bi-level pressure regulator is coupled to the patient interface via a second conduit and is configured to cyclically alternate the respiratory gas passing through the bi-level pressure regulator between a low-pressure level and a high-pressure level. The pneumatic circuit includes a pneumatic gas supply and a pneumatic cycler configured to output a cycling pressure level. The cycler is coupled to the bi-level pressure regulator via a third conduit. The bi-level pressure regulator cyclically alternates the pressure level of the respiratory gas between the low-pressure level and the high-pressure level with the timing defined by the cycling of the pneumatic gas.

A system and process for an oxygen flow control system for supplemental oxygen is provided, including a system with an optical flow sensor and 3-way solenoid that operate to detect inhalation and deliver a microburst of oxygen that is electronically controlled based on one or more parameters.

Disclosed herein are methods, systems, and devices for controlling a gas mixture within a mechanical ventilator. According to one embodiment, a computer implemented method includes receiving first peripheral arterial oxygen saturation (SpO.sub.2) data from a pulse oximeter via a pulse oximeter interface, wherein the pulse oximeter is configured to monitor a patient receiving invasive ventilation; determining a first mode of operation for a ventilator mechanism, wherein the ventilator mechanism is configured to provide at least a portion of the invasive ventilation; determining first partial pressure of oxygen (PaO.sub.2) data stored in a first lookup table using the first SpO.sub.2 data, wherein the first lookup table is derived from a sigmoid shaped oxyhemoglobin dissociation curve; determining first fraction of inspired oxygen in air (FiO.sub.2) data for setting a mixture in a gas blender in the ventilator mechanism based on the first PaO.sub.2 data and a variable offset; and providing the FiO.sub.2 data to the ventilator mechanism.

Systems and methods for calibrating oxygen sensors in ventilators are provided. An oxygen sensor is coupled in flow communication with a first oxygen gas source. A calibration circuit including a second oxygen gas source is coupled in flow communication with the oxygen sensor and a third oxygen gas source is coupled in flow communication with the oxygen sensor. A controller is configured to determine a calibration curve for the oxygen sensor via the calibration circuit by measuring the second oxygen gas source and the third oxygen gas source. Based on the calibration curve, an oxygen concentration value of the first oxygen gas source is measured and distributed.

Disclosed herein is a system and method for controlling oxygen supply equipments. The system is equipped with pressure sensors coupled to the oxygen supply equipments. Depending on the oxygen supply selected by a user for the patient, the pressure sensor monitors the current pressure of the preset oxygen supply during an inhalation phase corresponding to the patient. If the current pressure is less than a minima value or if a pressure drop rate is higher than or equal to a threshold rate or both, the system generates an alarm notifying the user to check the preset oxygen supply and in the meanwhile switches the preset oxygen supply from one oxygen supply equipment to another oxygen supply equipment or vice-versa.

The invention relates to a device for the dynamically adapting sealing of an organ or a body cavity, e.g. the windpipe (trachea) of an intubated and ventilated patient, wherein the sealing balloon element is produced via particularly rapid shifting of filling medium from an extracorporeal reservoir or an extracorporeal source to the sealing balloon, and wherein, in the dynamic sealing of the trachea according to the example case, a balloon-type foil body preferably formed with residual material in the diameter, i.e. exceeding the tracheal diameter, is in contact with the inner wall of the trachea in a sealing manner and with a pressure that is as constant as possible, wherein fluctuations in the balloon volume, caused by fluctuations in the intrathoracic pressure relating to the mechanics of breathing, are compensated as quickly as possible by supplying volume from an extracorporeal reservoir or an extracorporeal source, and the tracheal secretion sealing of the balloon is thereby kept continuous. This is both made possible by a sufficiently high-volume supply of the balloon filling medium to the cuff, and also prevents steps, gaps or ridges in the supply system, whereby volume flow directed towards the balloon can be minimised, which is crucial for a rapid-as-possible stabilising of the filling volume in the balloon, in particular with small pressure differences between 15 and 30 mbar that are driving the volume flow.