A method for manufacturing a medical instrument having a lubricating layer (coating layer) that exhibits excellent durability (particularly, sliding durability) is provided. The method for manufacturing a medical instrument is a method for manufacturing a medical instrument that includes a base layer and a lubricating layer carried on at least a portion of the base layer. The method includes applying a solution including a block copolymer having a structural unit derived from a reactive monomer having an epoxy group and a structural unit derived from a hydrophilic monomer, a choline derivative, and a solvent, on the base layer.

A medical device comprises a catheter and an aspiration pump. The catheter has a hybrid reinforcement to improve performance characteristics. The aspiration pump is cycled to improve aspiration efficacy.

An intravascular device delivery system includes an elongated member with a distal end cap and a delivery disc that are longitudinally movable using a disc handle. A main body of the disc handle is configured to move the distal end cap and a movable body of the disc handle is configured to move the delivery disc. The movable body is movable relative to the main body, and the main body and movable body are movable together.

The present disclosure can improve durability (particularly, sliding durability) of a surface lubricating layer while maintaining flexibility of a medical instrument. The medical instrument can include: a base whose surface is partially made of a polyester resin; an intermediate layer formed on at least a part of the surface of the base and containing a (meth)acrylic-modified polyester resin and a polyurethane resin; and a surface lubricating layer formed on an upper part of the intermediate layer and containing a block copolymer having a structural unit (A) derived from a hydrophobic monomer and a structural unit (B) derived from a hydrophilic monomer, in which at least one of the hydrophobic monomer and the hydrophilic monomer has a (meth)acryloyl group.

A vascular access sheath includes an inner support structure extends from a hemostasis valve toward a distal end section of the access sheath. An outer polymer is disposed over the inner support structure, where the outer polymer has an exterior surface extending from the hemostasis valve to a distal tip of the access sheath. The outer polymer has a consistent thickness along the access sheath and defines a greater durometer an intermediate section of the access sheath than at the proximal and distal end sections of the access sheath. The outer polymer also has a secondary lumen disposed between the exterior surface and the central lumen, where the secondary lumen extends at least partially along the length of the access sheath and is configured to receive a wire to reinforce the stiffness of the intermediate section of the access sheath.

A coated urinary catheter or urinary stent device includes a urinary catheter or stent which, in a deployed position, includes or defines a protective surface area and a protected surface area and a coating upon at least a portion of the protective surface area. The coating includes a lubricant and an antimicrobial and/or pH buffering material. The device is configured such that, upon application of negative pressure to the catheter or stent, tissue of a urinary tract of a patient conforms or collapses onto the protective surface area and is thereby prevented or inhibited from occluding one or more protected drainage holes, ports or perforations of the catheter or stent.

A method of making a ready-to-use catheter assembly is provided, which can be immediately used by a patient. The ready-to-use catheter assembly ensures that the catheter does not suffer from a loss of quality during its shelf life and a wetting medium are provided. The method comprises: placing a catheter with an inactivated hydrophilic outer surface at least along its insertable length and a wetting medium in a catheter package; treating the catheter package with the catheter and the wetting medium with electro-magnetic and/or particle radiation while at least initially the hydrophilic outer surface at least along the insertable length of the catheter remains inactivated; and activating the hydrophilic outer surface at least along the insertable length of the catheter with the wetting medium during and/or after the radiation treatment and wherein the wetting medium decreases in viscosity when submitted to electro-magnetic and/or particle radiation.

A packaged catheter assembly having a catheter, a fluid reservoir, and an opaque pouch containing the fluid reservoir and catheter, wherein the pouch comprises a transparent or translucent window. The catheter may be a male urinary intermittent catheter. The window may correspond to the position of the fluid reservoir in the pouch. The window may correspond to the position of an indicator region of the pouch. The indicator region may be configured to indicate successful release of fluid from the reservoir. The catheter in the pouch may be hidden, for example by the fluid reservoir and/or a wall of the pouch. The pouch may comprise a retaining seal configured to restrict the movement of the fluid reservoir within the pouch.

A vasculature navigation system may include a dilator having a proximal end and a distal end located opposite the proximal end, the dilator comprising a guidewire lumen extending between the proximal end and the distal end, the dilator defining a proximal portion and a distal portion located opposite the proximal portion. In some embodiments, the vasculature navigation system also includes an access port located at the proximal end of the dilator, a distal port located at the distal end of the dilator, and a hemostasis valve coupled to the proximal portion of the dilator. The hemostasis valve may be configured to control fluid flow between the proximal portion and the distal portion. In some embodiments, a flush port is coupled to the proximal portion of the dilator and located distal to the hemostasis valve, and the flush port is coupled to a fluid supply source.

The disclosure generally relates to adjustable sheath devices for insertion into the body to provide intravascular access to various medical devices, involving a dynamically expandable sheath capable of expanding within the blood vessel when a medical device is passed through the sheath and retracting back to almost its original size when the medical device is removed from the sheath. Embodiments generally comprise a rigid collar and an elongated sleeve comprising a continuous elastomeric outer layer and an expandable inner layer.