A persistent perfusion sheath assembly can be used for the passage of an intravascular medical device while maintain a flow passage in the vessel. The sheath assembly passes through an arteriotomy and can include a first lumen configured for the passage of a medical device, a second lumen configured to allow a flow of fluid from a location in the blood vessel upstream of the arteriotomy to a location downstream of the arteriotomy. The sheath assembly can further include a stylet, a sleeve or an additional sheath configured to selectively open and close the flow of blood between upstream and downstream of the arteriotomy. The sheath assembly can further include a closure device distal of the arteriotomy, the closure device configured to control blood flow through the arteriotomy.

A medical liquid injection device including a catheter shaft having a first lumen, and a connector being connected to a proximal end portion of the catheter shaft and including a second lumen communicating with the first lumen. The connector is formed with a weak portion extending from an outer peripheral surface of the connector to an inner peripheral surface of the connector and being weaker than another portion of the connector.

A blunt-tipped cannula needle for injection of fluid into the subcutaneous tissue around a vein. The cannula needle includes a tubular side wall having three straight sections, each section having a central axis. The second central axis is angled away from the first central axis at a first preselected angle in a first plane. The third central axis is angled away from the second central axis at a combination of a preselected second angle and a preselected third angle, such that the third central axis is effectively angled away from the second central axis both at the second angle in the first plane and at the third angle in a second plane perpendicular to the first plane. A distal end section of the needle in the third straight section has a plurality of apertures that at least substantially face the second central axis.

A catheter assembly includes a shaft with two non-communicating lumens for simultaneous inflow and outflow of fluids from a vein. A return lumen extends to an outlet assembly at the tip. A draw lumen includes an inlet assembly, proximally of the outlet assembly, with multiple openings to avoid blockage causing pressure elevation due to suction. The draw lumen has a larger crescent-shape profile while the return lumen has a smaller, circular profile within the arms of the crescent shape.

The present disclosure provides an apparatus including a first tubular housing including a first exit port and a second tubular housing including a second exit port. The apparatus also includes a third tubular housing coupled to at least one of the first tubular housing and the second tubular housing such that each of the first tubular housing, the second tubular housing, and the third tubular housing are fixed with respect to one another. The apparatus also includes a first catheter including a first plurality of outlets and is configured to be positioned at least partially within the first tubular housing. The apparatus also includes a second catheter including a second plurality of outlets and is configured to be positioned at least partially within of the second tubular housing. The apparatus also includes a pressure transducer line positioned in the third tubular housing and a pressure transducer coupled to the pressure transducer line.

The present embodiments provide systems and methods suitable for delivering an agent including a plurality of particles to a target site. In example embodiments, a system suitable for delivering an agent to a target site includes a catheter having a first wall defining a lumen sized for delivery of the agent to the target site. The catheter has a distal end terminating with a primary opening of the lumen, an opposing proximal end, and a longitudinal axis extending between the distal end and the proximal end. At least one secondary opening is formed at the distal end, wherein the secondary opening is configured to allow fluid to flow through the secondary opening to create a steady flow of fluid at an angle with respect to the longitudinal axis and prevent the plurality of particles from flowing through the secondary opening.

This disclosure includes intraluminal tubes comprising: an elongated tube (e.g., having a proximal portion, a distal portion configured to be disposed inside of an internal cavity of a patient, and a sidewall defining a lumen extending from the proximal portion to the distal portion, the distal portion defining one or more openings in fluid communication with the lumen) and a plurality of deployable tines, each coupled to the tube and disposed outside the sidewall of the distal portion, where each tine is movable from a collapsed state to a deployed state in which a portion of the tine extends laterally away from the distal portion of the tube. In some of the present intraluminal tubes, the sidewall of the distal portion defines a plurality of longitudinal grooves, and each tine is disposed in a different one of the grooves when the tines are in the collapsed state.

An introducer assembly includes a plurality of selectable side holes through which a fluid can be delivered. In some examples, an introducer assembly includes an outer elongated body defining a plurality of outer body side holes and an inner elongated body defining a plurality of inner body side holes. The inner elongated body is configured to rotate relative to the outer elongated body between a first rotational orientation in which a first subset of outer body side holes aligns with a first subset of inner body side holes and the inner elongated body blocks fluid flow out of the outer elongated body through a second subset of outer body side holes, and a second rotational orientation in which the second subset of outer body side holes aligns with a second subset of inner body side holes and inner elongated body blocks fluid the first subset of outer body side holes.

Disclosed embodiments include apparatuses, systems, and methods for assessing collateral ventilation. An illustrative embodiment includes a flexible insertion catheter device includes an outer tube having an inner diameter. The outer tube includes a plurality of ports at a distal end and an occlusion device filling port located proximal from the plurality of ports. Also, the flexible insertion catheter device includes an inner tube receivable within the outer tube. The inner tube includes a flow lumen and an outer diameter less than the inner diameter of the outer tube. The flexible insertion catheter device further includes an occlusion device attachable to the outer tube and configured to selectively seal a bronchial passageway to occlude a lobe of a lung.

A direct stream hydrodynamic catheter system is provided for the removal of thrombus, lesions and the like including provisions for the infusion of drugs, lysing fluids and the like into a blood vessel. Physician controlled powered direct fluid jet streams emanate from a fluid jet emanatory in the form of robust radially directed fluid jet streams to impinge upon and ablate difficult and strong thrombus and lesions within a blood vessel. Effluent aspiration is controlled by an exhaust regulator in the form of a roller pump, but effluent removal can be assistingly influenced by the fluid pressure associated with the radially directed fluid jet streams.