Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

A method of treating a patient's joint having opposing joint surfaces includes providing an elongate member having a proximal end, a distal end and an expandable member near the distal end. The expandable member is positioned in the joint between the joint surfaces and expanded so as to separate the joint surfaces away from one another into a distracted position. The joint is manipulated while in the distracted position so that the joint is distracted and in flexion. A diagnostic or therapeutic procedure is then performed on the joint while maintaining the joint in the flexed and distracted position.

A catheter tip having a spring element that imparts longitudinal flexibility, pushability and radial rigidity to the catheter tip, thereby improving deliverability, is provided. The spring element also provides radial support to the distal edge of the catheter tip. The spring element may taper distally, but may have a substantially constant inner luminal diameter. The spring element may be partially covered or embedded, leaving its distal end exposed. The spring element may also include spaced coils in a proximal region. The apparatus may be used with any interventional catheter system, but is particularly suitable for use with balloon-expandable stent systems and balloon-angioplasty systems, where flexibility of the catheter tip and minimal flaring of the distal edge of the catheter tip is desirable.

Various embodiments of the present disclosure can include flexible catheter tip. The flexible catheter tip can include an inboard understructure that defines a tip longitudinal axis, wherein the inboard understructure can be formed from a first continuous element that includes a first rectangular cross-section. An intermediate inboard covering can be disposed about the first continuous element that forms a distal portion of the inboard understructure. An outboard understructure can extend along the tip longitudinal axis, wherein the outboard understructure can be formed from a second continuous element that includes a second rectangular cross-section. An intermediate outboard covering can be disposed about the second continuous element that forms a distal portion of the outboard understructure.

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

A catheter assembly includes: a catheter; and an inner needle inserted through the catheter. The catheter includes: a catheter body; and a flexible portion that is located at a distal portion of the catheter body and forms a most distal portion of the catheter. An elastic modulus of the catheter body is greater than an elastic modulus of the flexible portion. The catheter has a mixed region in which the catheter body and the flexible portion overlap each other in a radial direction.

A catheter (100) includes a resin-made distal tip (80) linked to a distal end of a catheter body (10), and the distal tip (80) has a distal lumen (81) having an open distal end. The distal lumen (81) communicates with a lumen (31). The catheter (100) is an inactive type microcatheter in which an outer diameter of the distal end of the catheter body (10) is 0.6 mm or smaller and a maximum outer diameter of the distal tip (80) is 0.6 mm or smaller. A dimension of a marker (70) in an axial direction of the catheter body (10) is smaller than the maximum outer diameter of the distal tip (80), and the length of the distal tip (80) in the axial direction of the distal tip (80) is 3 times to 18 times the maximum outer diameter of the distal tip (80).

A urinary catheter with deflectable tip, comprising a hollow catheter body configured to be inserted within the urethra of a patient, the catheter body having an elongate portion, a tip portion near a distal end of the elongate portion and an engagement portion spaced from the distal end where a user can grasp the catheter, the tip portion being deflectable for the purpose of steering the catheter within the urethra to allow the catheter to follow a natural curvature of the urethra, the tip portion being movable from a generally straight condition to a deflected condition wherein deflection of the tip portion occurs while the elongate portion remains generally straight.

The present embodiments provide delivery systems for facilitating orientation of a prosthesis in a bodily passage. In one example, a system comprises an inner cannula having proximal and distal regions, and further comprises an atraumatic tip having a proximal end, a distal end, and a central region disposed therebetween. At least a portion of the atraumatic tip may be coupled to the proximal region of the inner cannula. A plurality of orientation struts are provided having a retracted delivery state, an expanded deployed state, and a retracted withdrawal state. The plurality of orientation struts each have apices that are oriented proximally relative to the atraumatic tip in the retracted delivery state, are oriented radially outward relative to the atraumatic tip in the expanded deployed state, and are oriented distally relative to the atraumatic tip in the retracted withdrawal state.

A urinary catheter with an actively deflectable tip, the tip portion being deflectable for the purpose of steering the catheter within the urethra to allow the catheter to follow a natural curvature of the urethra, when inserted into the urethra by a user. The described catheter includes features of the catheter described in PCT/AU2020/050972, but includes a number of modifications and variations, which may allow additional benefits to those of the previously described catheter.