A drug delivery device is formed from an elastic sleeve deployed around a core, with first and second edge portions inwardly inverted. When a fluid is introduced between the core and the sleeve, the sleeve inflates to form a reservoir with a pressure of the fluid pressing the inwardly-inverted extremities portions against the core. The device is preferably anchored by providing a stem of conformable material which is depressed by pressure applied by adjacent edges of a layer of tissue to achieve tissue-wedged anchoring of the device.

Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of fabricating, deploying, inflating, locating, tracking, monitoring, deflating, and retrieving the same are provided.

Devices and methods for treating obesity are provided. More particularly, intragastric devices and devices for inflating and methods of fabricating, deploying, inflating, monitoring, and retrieving the same are provided.

An inflation and deflation assembly includes an interface member including a proximal connector portion and distal resilient fingers cantilevered from an intermediate body portion distal of the proximal connector portion. A coupling device is formed with a lumen that has a proximal lumen portion and a distal lumen portion and a constriction portion intermediate the proximal lumen portion and the distal lumen portion. In a coupling orientation, the interface member is introduced into the coupling device and the resilient fingers bend radially inwards upon abutting and passing through the constriction portion.

An implant delivery system can be configured to deliver an inflatable implant into a bladder via a urethra. The delivery system can comprise an elongate tubular body, an inflation tube and an implant decoupler. The tubular body can comprise a central lumen configured to hold an inflatable implant in an initial un-inflated state for delivery of the implant into the bladder. A method of use can include passing a distal tip of the elongate tubular body into the bladder. The implant can be inflated and released into the bladder.

This disclosure provides a self-sealing system of a balloon system implanted in vivo. The balloon system includes a balloon, a catheter and a filling. The balloon includes a self-sealing valve penetrated by and hermetically connected to the catheter. A distal end of the self-sealing valve is provided with an inverted pocket and a sealing belt. The catheter penetrates through a hole in the self-sealing valve and enters the inverted pocket. The balloon is packaged in a capsule before being swallowed. One end of the catheter is connected to the self-sealing valve on the balloon while the other end is left outside the capsule. The catheter has a length, making an in-vitro end leave outside an oral cavity during use. The sealing belt makes the distal end of the inverted pocket be tightly closed after the filling is full and the catheter is removed, thereby preventing the filling from leaking out.

A drug delivery device is formed from an elastic sleeve deployed around a core, with first and second edge portions inwardly inverted. When a fluid is introduced between the core and the sleeve, the sleeve inflates to form a reservoir with a pressure of the fluid pressing the inwardly-inverted extremities portions against the core. The device is preferably anchored by providing a stem of conformable material which is depressed by pressure applied by adjacent edges of a layer of tissue to achieve tissue-wedged anchoring of the device.

An example medical device delivery system is disclosed. The delivery system includes an inflation shaft having a first lumen, a second lumen and a distal end region, the distal end region including an elongated tip. The delivery system also includes a detachment shaft extending along a portion of the inflation shaft. The delivery system also include a delivery shaft having a proximal end region, a distal end region and a lumen extending therein. The delivery system also includes an occlusive member positioned within at least a portion of the lumen of the delivery shaft, wherein the occlusive member is configured to expand and seal the opening of a left atrial appendage. Further, a portion of the elongated tip is removeably engaged with the occlusive member.

A breast cavity spacer device, a kit for performing a biopsy and a method of performing a biopsy, such as for use with a percutaneous lumpectomy, is provided. The breast cavity spacer device includes a catheter. A self-sealing balloon member is removably and fluidly coupled on one end of the catheter. An umbrella valve is coupled to the catheter adjacent the balloon member, the umbrella valve being configured to fluid flow into the balloon in response to fluid flow from an end of the catheter opposite the balloon and prevent fluid flow from the balloon when fluid flow from the end of the catheter is stopped.

Devices and methods for treating obesity are provided. More particularly a device for assisting a patient in swallowing an intragastric balloon is provided, comprising an elongate tube, a gastric balloon assembly reversibly attached to an orifice of the elongate tube and comprising an inflation catheter engaged with a gastric balloon, a handle member, and an engagement subassembly comprising a female portion and a male portion and configured and arranged for threading the inflation catheter into and engaging the elongate tube.