A device, system, and method for performing a variety of treatment procedures safely with a single treatment device. For example, a system is provided that includes a treatment device with a highly conformable balloon that is inflated at a constant pressure and that remains “soft” during use, which enhances balloon-tissue contact, treatment efficacy, and patient safety. In one embodiment, a system for ablating tissue comprises: a treatment device including a highly conformable balloon; a control unit including a fluid supply reservoir in fluid communication with the highly conformable balloon, the control unit being configured to deliver fluid from the fluid supply reservoir to the highly conformable balloon such that the highly conformable balloon is maintained at a balloon pressure of between 0.2 psig and 3.0 psig.

An everting balloon system is disclosed that can be used for the placement of an IUD within the uterine cavity of a female patient. The everting balloon system with IUD can be used to access a uterine cavity at specific locations in the fundus. A one-handed IUD delivery system for placement with an everting catheter is disclosed. An IUD loading system for placement within an everting catheter is disclosed. The everting catheter with an IUD can simplify the process of IUD placement within the uterine cavity.

In some examples, a catheter includes one or more balloons positioned between an inner wall and an outer wall of an elongated body of the catheter. The one or more balloons are configured to expand through one or more inner wall openings defined by the inner wall and into an inner lumen of the catheter, as well as through one or more outer wall openings defined by the outer wall, e.g., to extend radially away from an outer surface of the outer wall of the catheter. In some examples, the one or more balloons are configured to expand radially inward through the one or more inner wall openings and into the inner lumen of the catheter to contact (e.g., directly contact) a guidewire positioned within the inner lumen.

A medical probe includes a shaft, an expandable membrane and a probe maneuvering assembly (PMA). The shaft is configured for insertion into a cavity of an organ of a patient. The PMA is located inside the expandable membrane and includes a first elastic element, which is fitted along a longitudinal axis of the PMA and is configured to expand the membrane by shortening the PMA, and to collapse the membrane by elongating the PMA. The PMA further includes a second elastic element, which surrounds at least a portion of the first elastic element and is configured to deflect the membrane relative to the longitudinal axis.

An everting balloon system is disclosed that can be used for the placement of an IUD within the uterine cavity of a female patient. The everting balloon system with IUD can be used to access a uterine cavity at specific locations in the fundus. A one-handed IUD delivery system for placement with an everting catheter is disclosed. An IUD loading system for placement within an everting catheter is disclosed. The everting catheter with an IUD can simplify the process of IUD placement within the uterine cavity.

A drug or agent coated balloon having a length which is adjustable in vivo is described herein. The balloon is configured to be coated or coatable with one or more drugs where the coating may be applied prior to advancement into a patient body or prior to balloon expansion within the patient body. The length of the expandable portion of the balloon is adjustable to approximate a length of the tissue region to be treated. Moreover, the drug-coated balloon may be used alone or it may be utilized to deploy luminal prostheses having one or more linked or otherwise coupled segments.

An apparatus for performing a medical procedure includes a balloon comprising an inflatable body. A first releasable or frangible connection is provided to maintain the body at a first diameter up to a first inflation pressure, and to release, such as by disconnecting, and thus allow the body to assume a second diameter, such as at a second inflation pressure greater than the first inflation pressure or upon a manual release of the connection by a clinician. Multiple releasable or frangible connections may be provided, including between portions (folds) of the inflatable body of the balloon. This disclosure also pertains to a non-compliant or semi-compliant balloon having a first inflation diameter corresponding to a first range of inflation pressures and a second inflation diameter corresponding to a second inflation pressure greater than the first range of inflation pressures.

A balloon catheter includes a shaft, and a balloon provided outside the shaft. A drug is provided on an outer surface of the balloon, and the balloon has at least a straight tube part. A change ratio of an outer diameter of the straight tube part, (D28−D24)/D24, is 1.1% or less. D24 is the outer diameter of the straight tube part when an internal pressure of 2.43 MPa (24 atm) is applied, and D28 is the outer diameter of the straight tube part when an internal pressure of 2.84 MPa (28 atm) is applied.

A dialysis catheter includes a first tubular member having a proximal portion, a distal portion, and an inflation lumen extending at least partially through the first tubular member. The catheter has a balloon at the distal portion of the first tubular member, the balloon being in fluid communication with the inflation lumen. A second tubular member has a proximal portion connected to an outer surface of the first tubular member. The second tubular member has a second lumen extending therethrough, with a second opening connected to the second lumen. A third tubular member has a proximal portion connected to the outer surface of the first tubular member and a distal portion partially detached from the rest of the catheter (e.g., a catheter body) over a first detachment length. The third tubular member has a third lumen extending therethrough with a third opening connected to the third lumen.

An everting balloon system is disclosed that can be used for biopsy within a body of a patient or animal. The everting balloon system can be used to access a bodily cavity or vessel for tissue specimen collection at specific bodily locations. The everting catheter system described simplifies the process of tissue biopsy.