Embodiments of the present invention provide a method of treating a stricture in a nonvascular body lumen such as urethral strictures, benign prostatic hyperplasia (BPH) strictures, ureteral strictures, esophageal strictures, sinus strictures, and biliary tract strictures. Embodiments of the present invention provide a method for treating at least one of benign prostatic hyperplasia (BPH), prostate cancer, asthma, and chronic obstructive pulmonary disease (COPD). The method can include delivering, for example, via drug coated balloon catheters, anti-inflammatory and anti-proliferative drugs (e.g., rapamycin, paclitaxel, and their analogues) and one or more additives.

In various embodiments, a device is provided comprising a balloon configured to expand to an expanded state in response to introduction of a fluid at a first pressure, wherein the fluid perfuses through the balloon above a second pressure, the second pressure being the same or greater than the first pressure. In various embodiments, a method comprising fabricating a balloon configured to expand to an expanded state in response to introduction of a fluid at a first pressure, wherein the fluid perfuses through the balloon above a second pressure, the second pressure being at or greater than the first pressure, disposing the balloon on an elongate member having a lumen, placing the lumen in fluid communication with an interior volume of the balloon.

Inflatable medical devices and methods for making and using the same are disclosed. The devices can be medical invasive balloons, such as those used for transcutaneous heart valve implantation, such as balloons used for transcatheter aortic-valve implantation. The balloons can have high strength, fiber-reinforced walls.

A balloon catheter includes a shaft inserted into a body; a balloon attached to the shaft on a distal end side and is expandable by an expansion fluid supplied from a side of a proximal end of the shaft; an elastic band wound around an outer periphery of an intermediate portion between a distal end portion and a proximal end portion of the balloon , and is configured to limit expansion of the balloon at the intermediate portion; and a covering member covering an outer periphery of the elastic band. The balloon is expandable to a maximum expansion diameter from a folded state, in accordance with pressure of the expansion fluid, the elastic band is expandable beyond the secured diameter, by being elastically deformed by the balloon expanding, and the covering member is expandable by being elastically deformed by the balloon or the elastic band expanding.

A parison for being blow molded into a medical balloon for a catheter includes a first tubular layer having a functional modification and a second tubular layer adapted for bonding with the first tubular layer to form the blow molded balloon. Related methods are disclosed.

Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for stent deployment, are modified with the addition of a reservoir of dry micelles. The micelle preparation is reconstituted and the micelles are mobilized when the aqueous solution used to inflate the balloons is injected into the catheter. The micelles are infused into tissue surrounding the balloon when pressurized fluid within the balloon leaks through the wall of the balloon.

A balloon in which a rupture in a circumferential direction can be prevented from occurring, and a method of manufacturing the same is disclosed. The balloon is configured to be arranged on a medical catheter, and includes a dilatable cylindrical portion formed with a birefringent polymer material. A ratio of the number of orientation distributions, calculated by dividing the number of orientation distributions of the cylindrical portion in a circumferential direction by the number of orientation distributions of the cylindrical portion in an axial direction, is less than 2.

An ultrasonic echogenic device (100) includes a base layer (1), an echogenic layer (2) covering the base layer (1) and adhered to the base layer (1) at least by a separate lower adhesive (4), an outer layer (3) covering the echogenic layer (2) and adhered to the echogenic layer (2) at least by a separate upper adhesive (5), wherein the ultrasonic echogenic device (100) is configured such that a rough interface is provided at a position where the echogenic material of the echogenic layer (2) contacts at least the upper surface of the upper adhesive (5) and the lower adhesive (4), and the outer surface of the outer layer (3) at least partially follows an undulation of the rough interface. An ultrasonic echogenic device (100) with a simple structure and easily formed is obtained.

A balloon catheter includes a shaft having a first shaft portion and a second shaft portion located on a proximal side of the first shaft portion, and a balloon covering and joined to the second shaft portion. The first shaft portion is more flexible than the second shaft portion and has a length in an axial direction of 1.5 cm or more.

In some examples, a medical device includes a balloon inflatable to an inflated configuration. The balloon includes an outer layer coextruded on an inner layer. The outer layer has a maximum radial ratio that is lower than that of the inner layer.