A clot retrieval device is provided. The clot retrieval device includes a capturing basket having an opening at a proximal end where the capturing basket is deployable downstream from a clot in a blood vessel. The capturing basket is configured to surround a portion of the clot and the opening in the proximal end of the capturing basket is configured to reduce in size such that the capturing basket conforms around the portion of the clot and be retrieved after the capturing basket conforms around the portion of the clot.

The present disclosure describes flow stagnation control components that allow improved flow control in systems including injection members, while also limiting the creation of regions of little to no flow in the vasculature, resulting in low flow zones or dead zones. The flow stagnation control components can be formed as an imposed minimum conductance component or a controlled flow partitioning system.

An inflatable balloon is provided. The balloon includes a central lumen open at both ends of the balloon and connected to a gap formed in one sidewall of the balloon. This arrangement may provide the balloon with a generally C-shaped profile with the open central lumen within the balloon along a center axis thereof, such as to allow for perfusion. The balloon may also include an inflation port offset from a central axis and a shaft including an inflation lumen connected to the inflation port. A sheath may also be provided with a window through which the balloon may project in use.

Devices, systems, and methods for treating a blood flow passage are discloses herein. In one example, a treatment device includes an expandable element configured to be positioned within the passage and a reinforcing element. The expandable element may have an expanded configuration in which the expandable element defines a lumen therethrough. The reinforcing element may be positioned within the lumen of the expandable element. The reinforcing element may be coupled to the expandable element such that expansion of the expandable element causes the reinforcing element to radially expand, thereby creating a perfusion lumen through the device.

Disclosed is a double balloon fluid-carrying catheter including an outer conduit and a balloon. Two Luer ports are provided at a proximal end of the outer conduit, of which one is used to inflate and deflate the balloon and the other is used to flush a guidewire lumen, and the balloon is provided near a distal end of the outer conduit, wherein the balloon is provided with two balloons, namely a proximal balloon and a distal balloon, and there is a certain distance between the proximal balloon and the distal balloon; a proximal end of the proximal balloon is provided with a plurality of side holes on a wall of the outer conduit, the side holes conduct an inside and an outside of the outer conduit, and a distal end of the distal balloon is provided with a bridging reflow hole.

A method of embolizing a tumor includes advancing a distal end of a device having a catheter body and an occlusion structure to a target tumor site within a blood vessel of a body. The occlusion structure is activated within the blood vessel, and a real time pressure measurement in the vascular space distal to the activated occlusion structure is monitored. The method further includes waiting for a pressure drop in the vascular space distal to the activated occlusion structure and for the pressure drop to cause a blood flow reversal in branch vessels antegrade to the occlusion. An embolic substance is injected from the distal end of the delivery device to permit the reversed blood flow to carry the embolic substance into the vasculature of the target tumor and the device is withdrawn from the body. Other catheter assemblies and methods of use are also disclosed.

This patent document discloses perfusion catheters and related methods for treating complications related to CTO interventions or dilating a vessel occlusion while maintaining a passage through the treated vessel segment. A perfusion catheter can include an inflatable balloon coiled in a helical manner around a central axis into a series of windings. An inner surface of the series of windings, when inflated, can define a passage through the inflatable balloon. A catheter can also include an elongate shaft extending from a proximal portion to a distal portion, having an inner surface that defines a lumen for providing inflation fluid to, or withdrawing inflation fluid from, a distal end of the inflatable balloon. A catheter can further include a guidewire support tube including a lumen, separate from the lumen from the elongate shaft and the passage through the inflatable balloon, for receiving a guidewire.

A non-occluding drug-coated balloon catheter device for use in a blood vessel transporting blood comprises a catheter shaft including a guidewire lumen, a fluid lumen and a connector port. A balloon is mounted on the catheter shaft and includes an outer envelope surrounding the guidewire lumen in fluid communication with the fluid lumen; a drug coating applied on the exterior surface of the outer envelope; and at least one bypass lumen forming a passage extending from the proximal end of the outer envelope to the distal end of the outer envelope. When the balloon is positioned in a blood vessel and inflated, the exterior surface of the outer envelope presses the drug coating against the blood vessel and the bypass lumen is open between the distal end of the outer envelope and the proximal end of the outer envelope such that blood transport continues through the bypass lumen.

An apparatus and methods to form a tissue scaffolding are provided. The apparatus may include a catheter shaft extending from a proximal end to a distal tip, a distal balloon positioned on the catheter shaft proximal to the distal tip, and a proximal balloon positioned on the catheter shaft proximal to the distal balloon. The apparatus may further include an intermediate balloon positioned on a distal segment of the catheter shaft proximal to the distal balloon and distal to the proximal balloon. The intermediate balloon and the distal segment each include a translucent material. A light fiber may extend through the distal segment. A first lumen and a second lumen may be arranged in the catheter shaft, the first lumen comprising a first port located between the distal balloon and the intermediate balloon, and the second lumen comprising a second port located between the intermediate balloon and the proximal balloon.

A non-occluding drug-coated balloon catheter device for use in a blood vessel transporting blood comprises a catheter shaft including a guidewire lumen, a fluid lumen and a connector port. A balloon is mounted on the catheter shaft and includes an outer envelope surrounding the guidewire lumen in fluid communication with the fluid lumen; a drug coating applied on the exterior surface of the outer envelope; and at least one bypass lumen forming a passage extending from the proximal end of the outer envelope to the distal end of the outer envelope. When the balloon is positioned in a blood vessel and inflated, the exterior surface of the outer envelope presses the drug coating against the blood vessel and the bypass lumen is open between the distal end of the outer envelope and the proximal end of the outer envelope such that blood transport continues through the bypass lumen.