An implantable vascular access port has a main port body with one or more hollow internal chambers formed therein each with a floor at the base of the internal chamber. The port body has an outlet aperture formed in a sidewall there of the internal chamber. One or more parallel, lateral, or angled-access apertures, relative to the port floor and associated septa are located opposite the outlet aperture in the main port body in a sidewall there of (parallel or lateral or angled-access aperture or septum), with at least a one perpendicular-access aperture and septum located opposite the floor of the internal chamber(s). The port chamber in the area of the outlet aperture has an at least partially conical shape directionally aligned with the parallel or lateral or angled-access aperture and septum, with said outlet aperture in contiguity a reversible outlet tube or port body needle locking mechanism.

A low-profile access port for subcutaneous implantation within the body of a patient is disclosed. The access port includes a receiving cup that provides a relatively large subcutaneous target to enable a catheter-bearing needle to access the port without difficulty. In addition, the access port includes a valve/seal assembly to permit pressurized fluid injection through the port while preventing backflow. In one embodiment, therefore, a low-profile access port comprises a body including a conduit with an inlet port at a proximal end thereof, and a receiving cup. The receiving cup is concavely shaped to direct a catheter-bearing needle into the conduit via the inlet port. The receiving cup is oriented substantially toward a skin surface when subcutaneously implanted within the patient to ease needle impingement thereon. A valve/seal assembly disposed in the conduit enables passage of the catheter therethrough while preventing fluid backflow.

An arteriovenous graft system is described. The arteriovenous graft system includes an arteriovenous graft that is suited for use during hemodialysis. In order to minimize or prevent arterial steal, at least one valve device is positioned at the arterial end of the arteriovenous graft. In one embodiment, for instance, the arteriovenous graft systems includes a first valve device positioned at the arterial end and a second valve device positioned at the venous end. In one embodiment, the valve devices may include an inflatable balloon that, when inflated, constricts and closes off the arteriovenous graft. If desired, a single actuator can be used to open and close both valve devices.

Catheters, catheter ports, connectors, and related methods are disclosed herein, e.g., for drug delivery to a subject. The catheters and catheter ports can include various features to facilitate dosing protocols that require multiple injections, and/or for reducing or eliminating damage that may occur to the catheter, port, or patient tissue as a result of multiple injections.

An access port for subcutaneous implantation is disclosed. The access port may include a body for capturing a septum for repeatedly inserting a needle therethrough into a cavity defined within the body. The access port may further include at least one feature structured and configured for identification of the access port subsequent to subcutaneous implantation. Methods of identifying a subcutaneously implanted access port are also disclosed. For example, a subcutaneously implanted access port may be provided and at least one feature of the subcutaneously implanted access port may be perceived. The subcutaneously implanted access port may be identified in response to perceiving the at least one feature. In one embodiment, an identification feature is included on a molded insert that is sandwiched between base and cap portions of the access port so as to be visible after implantation via x-ray imaging technology.

A low-profile access port for subcutaneous implantation within a patient. The access port can include a set of receiving cups which can be placed in fluid communication with a catheter. The set of receiving cups can provide a greater skin surface with which to access the port to avoid repeated penetrations at a single locus, such as during consecutive dialysis treatments. The access port can alternatively include needle penetrable arms or elongate chambers that also have a slim, low profile. The access port can include a needle guide to direct subsequent needle access to different insertion points to permit healing at the previous insertion points. The access port can be formed of a modular construction with a first conduit, a second conduit, and an outer shell. The outer shell can include a proximal portion and a distal portion. The access port can include a stem assembly and a locking member.

A method for manufacturing an implantable access port, including forming a port body. The port body can include a fluid cavity located in a central region, the fluid cavity having a base surface lying in a first plane, and a plurality of recessed sections located in a peripheral region surrounding the central region, the plurality of recessed sections having a depth extending from a bottom surface of the peripheral region through the first plane. The method further includes locating a septum over the fluid cavity, and positioning a radiopaque insert in the plurality of recessed sections.

An implantable access port for use in transferring fluid transdermally between an external fluid storage or dispensing device and a site within a patient is disclosed. The access port includes a body, at least two reservoirs defined within the access port body, and at least one septum secured to the body and enclosing the reservoirs within the body. The access port also includes reservoir outlets defined within the reservoirs. The access port also has body conduits defined within the body and in fluid communication with the reservoir outlets and external openings defined in the exterior of the body. An implantable access port and system for use in apheresis is also provided that includes an implantable access port, at least one needle, and a catheter that is fluidly connected to the access port.

Described herein are implantable ports including a housing with a fluid receptacle, a port stem in fluid communication with the fluid receptacle, and a septum covering the fluid receptacle. The ports may be configured to reduce the priming volume by including a plurality of fluid-locked chambers and/or one or more base mats. The ports may also include a hydrophobic coating on one or more surfaces thereof.

A power-injectable access port and methods of making are described. One method of making includes forming a power-injectable access port housing, creating a screen including one or more apertures through the screen in the shape of one or more alphanumeric characters, suspending a radiopaque material in a silicone material to form a radiopaque suspension, and depositing the radiopaque suspension onto a surface of the power-injectable access port housing through the one or more apertures of the screen to create at least one radiopaque identification feature. The at least one radiopaque identification feature may have a thickness protruding from an outer surface of the port base such that it is perceivable by sight and touch prior to implantation of the power injectable access port, and is observable via imaging technology subsequent to subcutaneous implantation of the power-injectable access port.