A needle suitable for use by inserting thru tissue for gaining access to target location. A needle is provided which has improved functionality and reducing complexity of procedure. The needle is comprised of an end with side aperture towards the tip portion, which is connected via conduit portion to the needle port. In one embodiment, the needle is comprised of a hollow needle with a port and a distal atraumatic end towards which there is a single aperture on the side wall, wherein a wire can be moved within the needle without damaging the wire. In other embodiment, the needle is comprised of a hollow needle with more than one port connected to tip portion towards which there are multiple apertures on the side wall, wherein a contrast or fluid injected from one port and wire can be inserted and removed from another port of the needle.

Devices, methods, and kits are presented that allow for simplified stent placement and stent retention in a biological vessel other than a blood vessel, and especially biliary stent placement in an antegrade manner. The devices and methods advantageously allow for shortened imaging and stent placement time, and substantially improve tolerability and/or retention of the stent in the vessel, and in further beneficial aspects, contemplated stents form a composite fluid path to facilitate drainage of the vessel. Still further, the devices and methods presented herein reduce or even entirely eliminate partial deflation of the peritoneal space during imaging and stent placement and so prevent exposure of operating personnel to vented gases carrying harmful agents.

Provided herein is a delivery system and method for delivering a depot within a submucosal pocket comprising a housing including a central opening and a fluidic connector configured to secure to a fluidic supply, an extension configured to at least partially collapse within the central opening of the housing, a supply conduit configured to extend through the housing and the extension, the supply conduit configured to deliver a lift solution configured to form a submucosal pocket within a subject, and a depot conduit configured to extend through the housing and the extension and to deposit a depot within the submucosal pocket, where when the extension is configured to at least partially collapse within the housing, whereby at least one of the supply conduit or depot conduit, or both advance distally past a distal end of an endoscope.

Devices, methods, and kits are presented that allow for simplified stent placement and stent retention in a biological vessel other than a blood vessel, and especially biliary stent placement in an antegrade manner. The devices and methods advantageously allow for shortened imaging and stent placement time, and substantially improve tolerability and/or retention of the stent in the vessel, and in further beneficial aspects, contemplated stents form a composite fluid path to facilitate drainage of the vessel. Still further, the devices and methods presented herein reduce or even entirely eliminate partial deflation of the peritoneal space during imaging and stent placement and so prevent exposure of operating personnel to vented gases carrying harmful agents.

Devices, methods, and kits are presented that allow for simplified stent placement and stent retention in a biological vessel other than a blood vessel, and especially biliary stent placement in an antegrade manner. The devices and methods advantageously allow for shortened imaging and stent placement time, and substantially improve tolerability and/or retention of the stent in the vessel, and in further beneficial aspects, contemplated stents form a composite fluid path to facilitate drainage of the vessel. Still further, the devices and methods presented herein reduce or even entirely eliminate partial deflation of the peritoneal space during imaging and stent placement and so prevent exposure of operating personnel to vented gases carrying harmful agents.

The gastrostomy catheter includes a shaft in which a lumen is provided, a flexible bumper which is provided at a tip of the shaft, and a wire which has elasticity and can bias the bumper in a diameter-increasing direction and restricts deformation of the bumper in a diameter-decreasing direction. At least a portion on a tip side of the wire biases the bumper in the diameter-increasing direction or restricts the deformation of the bumper in the diameter-decreasing direction by the elasticity of the wire in a state in which the wire is disposed in the bumper.