A method comprises positioning a medical appliance having a primary pressure sensor at or within a patient incision site and supplying an insufflation fluid to the patient cavity. The method further comprises measuring a pressure in the patient cavity by the primary pressure sensor and controlling the supply of insufflation fluid by an insufflator to the patient cavity based at least on the measured pressure. The method further comprises determining, by a processor associated with the insufflator, that the measured pressure may be inaccurate and, in response to determining that the measured pressure may be inaccurate, controlling, by the insufflator, the supply of the insufflation fluid to the patient cavity based at least on a pressure measured by a backup pressure sensor.

A vascular introducer sheath device comprising a tubular main shaft and a main hub attached to the proximal end of the main shaft. Attached to the proximal end of the main hub is a header hub, which has a first arm and a second arm. The header hub is attached to the main hub in a releasably locked configuration. As such, the header hub is functionally detachable from the main hub. The header hub and the main hub could together have a twist-on or snap-on mating mechanism. An example of such a mating mechanism is a male lock fitting on the header hub and a female lock fitting on the main hub. Further, there could be a side port on the main hub and a side port on the header hub, wherein the side ports for the main hub and header hub are oriented on a same plane when the header hub and the main hub are in locked configuration.

A vascular access device including a catheter adapter, a port opening, and an elastomeric valve. The catheter adapter extends along a longitudinal axis and includes a proximal end, a distal end, and a lumen extending therebetween. The port opening is formed in a surface of the catheter adapter in fluid communication with a side port of the catheter adapter and the lumen. A structural geometry of the port opening directs a fluid into the lumen in a proximal direction. The elastomeric port valve is disposed within the lumen and configured to deform in response to a transverse force applied thereto. A proximal gap may result between the inner wall forming the lumen and a proximal side of the elastomeric port valve, thereby opening a fluid path.

A system includes a first port comprising a first inlet, a first outlet, a first fluid pathway extending from the first inlet to the first outlet, a second inlet, a second outlet, and a second fluid pathway extending from the second inlet to the second outlet. The system further includes one or more CSF catheters having a first lumen, a first distal opening in fluid communication with the first lumen, a second lumen, and a second distal opening in fluid communication with the second lumen. The one or more CSF catheters are, or are configured to be, operatively coupled with the first implantable device such that the first lumen is in fluid communication with the first fluid pathway and the second lumen is in fluid communication with the second fluid pathway. At least the first distal opening is configured to be placed in the CSF-containing space. The system further includes a second port having a third inlet, a third outlet, and a third fluid pathway extending from the third inlet to the third outlet. The system also includes a port catheter configured to operatively couple the third fluid pathway to the second fluid pathway.

An implantable cranial medical device includes a first fluid flow path, a second fluid flow path, and upper flange portion, and a lower portion. The upper flange portion is configured to rest on a skull of a subject about a burr hole. The lower portion is configured to be placed within the burr hole. The first fluid flow path may extend from a first opening in the upper flange portion to a first opening in the lower portion. The second fluid flow path may extend from a second opening in the upper flange portion to a second opening in the lower portion.

The present disclosure relates to implantable encapsulation devices for housing a biological moiety or a therapeutic device that contains a biological moiety. Particularly, aspects of the present disclosure are directed to an implantable apparatus that includes a distal end, a proximal end, a manifold including at least one access port positioned either at the distal end or the proximal end, and a plurality of containment tubes affixed to the manifold and in fluid communication with the at least one access port. Additionally, the encapsulation device may contain a flush port and a tube that are fluidly connected to the manifold. The containment tubes may contain therein a biological moiety (e.g., cells) or a therapeutic device (e.g. a cell encapsulation member).

A vascular access tube (2) for a fluid subject to a driving pressure comprises a wall (4) defining a main lumen. A portion of the wall comprises an access port (10) for an object (14) to be introduced through the wall. The access port comprises a biasing structure (12) which provides a self-closing behaviour that is sufficiently strong to remain fluid-tight when exposed to a driving pressure of up to 50 mmHg. The access port is therefore sufficiently fluid-tight to contain pressurised fluid flowing through the vascular access tube.

According to the present invention, blood access formed by a percutaneous terminal for hemodialysis is performed, the percutaneous terminal provided with: a contact body comprising a biocompatible member that comes into contact with skin tissue inside and outside a living body; a tubular body having one end connected to an artery and the other end connected to a vein; a blood removal tubular body having one end connected to a side surface of the tubular body and supplying blood to an external blood circuit; and a retransfusing tubular body having one end connected to the vein and the other end connected to a retransfusing portion of the blood circuit, wherein the other end of the blood removal tubular body and the retransfusing tubular body are located at a central portion of the contact body. Furthermore, provided is a hemodialysis system that is less burdensome for a patient and enables stable blood access.

Endovascular drug delivery systems and methods are disclosed herein for delivering a therapeutic agent to the intracranial subarachnoid space of a patient, and/or deploying an endovascular drug delivery device distal portion in the intracranial subarachnoid space and a portion of the drug delivery device body in a dural venous sinus such that a therapeutic agent is delivered from the deployed drug delivery device into the intracranial subarachnoid space.

An apparatus for guiding cannulation with a dialysis needle of an arteriovenous dialysis access graft subcutaneously implanted in a body of a subject. The guiding apparatus comprises an elongated body member comprising a base portion terminating in longitudinal edges, a distance between the longitudinal edges of the base portion being substantially equal to a lateral dimension of the aces graft, and an elongated tubular sleeve defining an pocket having a longitudinal dimension and a lateral dimension configured to receive the body member. The body member is adapted to be received in the pocket of the sleeve for securing adjacent the subcutaneous access graft such that the inner surface of the base portion is aligned with a cannulation point of the graft for guiding location of a needle insertion.