A delivery adapter which may be used as an interface between a syringe and a catheter hub is described.

Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that are configured to be implanted within a patient. The apparatuses, systems, and methods may include a catheter configured to implant within the intraperitoneal space of the patient, an interior flow lumen, and at least one opening connected to the interior flow lumen for therapeutic agent delivery.

A medical connector for minimizing discomfort to a patient may include a substantially rigid inner body and a flexible outer body having a patient interfacing surface and coupled to at least a portion of the substantially rigid inner body. The patient interfacing surface may include a cushion material. The cushion material may be interposed between the substantially rigid inner body and the patient's skin when the medical connector is attached to the patient.

A fully implanted automatic disorder response system is devised to act as a backup “immune” system, automatically detecting and dispensing an enzyme, for example, deficient due to an inborn error of metabolism. In response to a disease, the agent released is one or more drugs. By directly pipeline-targeting agents through a closed system of drug reservoirs, fluid and electrical lines, and leak-free, durable, and safe tissue connectors to the site of disease, the system achieves a level of efficiency critically superior to the systemic dispersal of an agent into the circulation, fundamentally liberalizing the use of drugs. In comorbid disease, each morbidity is assigned to an arm or channel in a hierarchical control system. Beginning with symptomatic indicia sensors, data is analyzed and passed up through successively higher-level nodes that generate a cross-morbidity view passed up to an implanted microprocessor which effectuates a release of drugs calculated to optimize homeostasis.

A vascular access device including a catheter adapter, a port opening, and an elastomeric valve. The catheter adapter extends along a longitudinal axis and includes a proximal end, a distal end, and a lumen extending therebetween. The port opening is formed in a surface of the catheter adapter in fluid communication with a side port of the catheter adapter and the lumen. A structural geometry of the port opening directs a fluid into the lumen in a proximal direction. The elastomeric port valve is disposed within the lumen and configured to deform in response to a transverse force applied thereto. A proximal gap may result between the inner wall forming the lumen and a proximal side of the elastomeric port valve, thereby opening a fluid path.

Devices and methods for retrieving percutaneously implanted catheter systems such as a heart valve repair system. The devices include at least one locking connector at the distal end of a flexible elongated extension for coupling to an implanted tubular member. The locking connector may be a tubular anchor having a pair of distal prongs which are biased outward and face in a proximal direction, as well as an expandable auxetic midsection. Inserting the tubular anchor into the implanted tubular member flexes the distal prongs inward such that they prevent proximal movement of the tubular anchor. A user pulls on the proximal end of the tubular anchor to expand the auxetic midsection and lock the two pieces together. The devices and methods are particularly useful to attach extensions to implanted concentric tubes to enable relative axial force application.

Neurosurgical apparatus has a guidance device having a guide tube and a neurosurgical instrument for insertion into the guide tube. The inner surface of the guide tube is arranged, for example profiled, to at least partially engage the outer surface of the neurosurgical instrument when inserted therein. The guide tube thus guides the neurosurgical instrument along a predefined path through the guide tube. At least one of the guidance device and the outer surface of the neurosurgical instrument are configured to provide a fluid return path for carrying any fluid displaced from within the guide tube during insertion of the neurosurgical instrument into the guide tube. A seal may also be provided for sealing the fluid return path.

A patency system for maintaining a patency of an indwelling medical device including an elongated shaft configured to be at least partially received within a portion of the indwelling medical device, and at least one cleaner configured to at least partially dislodge debris formed within the indwelling medical device.

The invention relates to a vascular access device (10) for implantation onto a vessel wall, the access device comprising an tubular structure (12) to provide an access passage into the vessel via a hole in a vessel wall, a connector arrangement (20; 21) for attaching the tubular structure at said hole in the vessel wall, and a membrane structure (16A; 16B) sufficiently flexible to be collapsed for insertion through said hole and to be expanded to lie at least partially against an inner vessel surface thereby to surround the hole. The membrane structure comprises a membrane aperture (18) to provide a passage from inside the vessel into the tubular structure. The vascular access device further comprises a closing mechanism capable of closing the membrane aperture while the membrane structure is expanded against said inner vessel surface. There is also provided a method of implanting a vascular access device.

A valved introducer sheath (1) having a valve housing (17, 18) with a through-lumen and an inflatable cuff (2, 60, 70) disposed in the valve housing that can be inflated to occlude the through-lumen, is described. The device has an overflow tube (30) in fluidic connection with the inflatable cuff having a resiliently deformable overflow chamber (34). When the inflatable cuff is filled with inflation liquid, the cuff partly or fully occludes the through-lumen, thereby preventing blood pass through the lumen. When an interventional device is pushed through the lumen for use in a medical procedure, the pressure forces liquid from the cuff into the overflow tube, allowing the cuff to partly deflate. As the overflow chamber is resiliently deformable, the liquid is pressurised which maintains a seal between the inflatable cuff and the interventional device. Upon removal of the interventional device from the lumen, the overflow tube pushes fluid back into the cuff, allowing it to reinflate fully.