A medical device material impregnated with a combination of antimicrobial agents, the combination of antimicrobial agents comprising a first antimicrobial agent, the first antimicrobial agent being triclosan and at least a second antimicrobial agent, wherein the combination of antimicrobial agents provides the device material with antimicrobial activity and inhibition of resistant microbial mutations for of the order of, or greater than, 80 days.

An antimicrobial medical device for use during the placement of a catheter. The antimicrobial medical device includes a tubular body configured to receive the catheter through a lumen of the tubular body during an intravascular procedure and wall of the tubular body forms a liner between catheter and the patient's skin. The device further includes an antimicrobial material coupled with the tubular body so that in use the antimicrobial material inhibits microbe growth at the insertion site.

An exemplary ultraviolet (UV) arrangement, can be provided, which can include, for example, a lumen structured to be inserted into a body of a patient and pass a percutaneous structure therethrough into the body of the patient, wherein the lumen can be configured to disperse or provide a UV radiation, and an optical arrangement coupled to the lumen, and configured to generate the UV radiation, and provide the UV radiation to the lumen to be dispersed or provided by the lumen. The lumen can include a weave of a plurality of strands. The optical arrangement can include an optical fiber(s) coupled to the lumen at one of the strands. The optical arrangement can include a plurality of optical fibers coupled to the lumen, where the optical arrangement can include a plurality of diffusing rings, and wherein each ring can be connected to one of the optical fibers.

Invasive medical devices including a substantially non-eluting antimicrobial treatment are disclosed. One or more external and/or internal surfaces of the medical device include a substantially non-eluting copper-coated surface that assists in preventing microbial colonization of the coated surface. This in turn reduces the incidence of infection to the patient originating from the medical device. In one embodiment, a catheter assembly is disclosed and comprises an elongate catheter tube that defines at least one lumen, at least one extension leg including a luer connector, and a bifurcation hub including at least one fluid passageway that provides fluid communication between the extension leg and the lumen. A substantially non-eluting copper coating is disposed on a surface of at least one of the lumen, the extension leg, the luer connector, and the fluid passageway. The coating is applied via an electroless deposition process. A water-shed coating is disposed on the copper coating.

A stabilizing connector includes a connector portion and a stabilization portion. The connector portion is configured to couple to an access device. The connector portion defines at least one lumen that is configured to be placed in fluid communication with a lumen of the access device. The stabilization portion is coupled to the connector portion. The stabilization portion is configured to be placed in contact with a surface of a patient's skin to stabilize at least one of the stabilizing connector or the access device.

An obturator can include antimicrobial features which assist in sterilizing or maintaining the sterility of fluid contained within a vascular access device while the device is not being used for infusion or other access to the patient's vasculature. These antimicrobial features include antimicrobial coatings applied to various surfaces of an obturator and antimicrobial components bonded or otherwise secured to an obturator. Various combinations of antimicrobial coatings and/or components can be used on an obturator as necessary to provide a desired amount of antimicrobial agents within a particular enclosed volume of a vascular access device.

Methods and apparatus are disclosed for making and using adjustable epidermal tissue ingrowth cuff and catheter assemblies for transcutaneous placement to provide periodic or continuous external access for medical purposes to an interior body region of a patent who requires such medical treatment over an extended period of time.

A barrier system is provided for use in reducing infections associated with a percutaneous medical device, such as a catheter, that is disposed within a percutaneous incision. Such a barrier system can include: a barrier device having a skin-contacting surface and a catheter-receiving surface; and an adhesive composition configured for adhering to skin, the barrier device, and/or the catheter so as to form a barrier at or adjacent to an incision in the skin where the catheter is percutaneously inserted through the skin. The barrier device can include a conduit configured to receive the catheter. Alternatively, the barrier device can include a groove in a base surface that is configured to receive the catheter. A system that includes a medical device, the barrier device, and adhesive can also be provided.

Syringe assemblies comprising an absorbent pad containing disinfectant and a rotatable cap to ensure adherence to aseptic techniques for use in flush procedures for vascular access devices (VAD's) are described. Also described are methods of disinfecting vascular access devices.

The disclosed antimicrobial device securely attaches to an underlying substrate such that the insertion needle can puncture though the antimicrobial device for easy application and antimicrobial protection of the insertion needle. The antimicrobial device comprises a contact dressing with a contact dressing first surface and contact dressing second surface, opposite the contact dressing first surface. The contact dressing first surface has an adhesive and an antimicrobial agent. The insertion needle is inserted through the contact dressing. The adhesive and antimicrobial agent are on the contact dressing first surface adjacent the inserted insertion needle.