The disclosure relates to a subcutaneously implanted port device for establishing access to the vascular system of a patient requiring multiple blood treatments over an extended period of time. The systems, devices and methods disclosed herein may reduce miscannulation, promote intra-session hemostasis, and decrease the incidence of bacteremia and sepsis among other improvements and advantages. The devices include a port with a tapered seat for receiving an access tube, the first tapered seat having a proximal portion, a distal portion, and a conical section extending between the proximal portion and the distal portion; and an interface surface configured to engage a blood vessel or a vascular access catheter. The proximal portion of the tapered seat is configured to receive the access tube therethrough, and the tapered seat creates a mismatch fit with a diameter of the access tube when in use for an increase in flow during treatment.

Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.

A system for facilitating instrument delivery through a peripheral intravenous catheter may include a catheter adapter having a proximal end, a distal end, and a lumen extending there through. The catheter adapter may include a side port. The system may include an extension tube extending from the side port. The system may include a blood control valve disposed in the lumen of the catheter adapter. The system may include a peripheral intravenous catheter extending distally from the catheter adapter.

A barrier system is provided for use in reducing infections associated with post-operative surgical incision and/or a percutaneous medical device, such as a catheter, that is disposed within the surgical incision. Such a barrier system may include: a barrier device having a skin-contacting surface and a catheter-receiving surface; and an adhesive composition configured for adhering to skin, the barrier device, and/or the catheter so as to form a barrier at or adjacent to an incision in the skin where the catheter is percutaneously inserted through the skin. A tensioning anchor and associated system of two or more tensioning anchors is provided for post-operative wound closure. A method for applying and removing the barrier device and tensioning anchors is also provided.

According to one implementation an apparatus for bacterially disinfecting a surface is provided. The apparatus includes a flexible body that contains therein at least one radially emitting optical fibers that is configured to emit bacterial disinfecting light. The radially emitting fibers having an axial and/or radial freedom of movement within a channel in which it is housed inside the flexible body such that when the flexible body changes shape the axial and/or radial freedom of movement reduces the amount of tensile stress applied along the length of the radially as compared to an amount of tensile stress that would otherwise be applied to the radially emitting fiber in an absence of the axial and/or radial freedom of movement of the radially emitting fiber inside the channel.

Provided herein is a catheter system that includes an intravenous catheter assembly including a catheter defining a lumen extending between a distal end and a proximal end of the catheter and an access connector configured to provide access to the lumen of the catheter. The catheter system also includes a disinfecting probe coupleable to the access connector, with the disinfecting probe including a housing having a proximal end and a distal end, a lighting system disposed at least partially within the housing and configured to emit a disinfecting ultraviolet light, and an advancement member configured to advance a portion of the lighting system beyond the distal end of the housing and into the catheter, responsive to movement of the advancement member with respect to the housing, wherein the disinfecting ultraviolet light disinfects the lumen of the catheter upon being advanced therein by the advancement member.

A medical device material impregnated with a combination of antimicrobial agents, the combination of antimicrobial agents comprising a first antimicrobial agent, the first antimicrobial agent being triclosan and at least a second antimicrobial agent, wherein the combination of antimicrobial agents provides the device material with antimicrobial activity and inhibition of resistant microbial mutations for of the order of, or greater than, 80 days.

A percutaneous collar is made up of a central rigid ring and a flexible mesh inside a microporous silicone disc. The volume of the disc has a three-dimensional network of interconnected micropores forming microchannels connecting both external faces of the disc through the external micropores to the internal flexible mesh wherein the flexible mesh is formed by crossed longitudinal and radial elements or plates which form a plurality of holes.

The present invention relates to subcutaneously implanted graft-port systems, devices and methods for establishing access to the vascular system of a patient requiring multiple blood treatments over an extended period of time. The systems, devices and methods disclosed herein reduce miscannulation, promote intra-session hemostasis, and decrease the incidence of bacteremia and sepsis among other improvements and advantages. The devices include a port with a flattened plateau-like surface for receiving an access tube. The flat surface may include a tactile or visual guide to assist with placement of the access tube into the tapered seat. Optional valve mechanisms reduce the size and form factor of the implantable graft-port device and seals the conduit of the port closed to physiologic pressures until the valve is opened upon percutaneous insertion of the access tube. The access tube does not pass into the conduit. A mismatch fit between the access tube and tapered seat causes a decrease in the cross-sectional sealing area, a reduction in the overall device size, and an increase in blood flow during treatment. Lock solutions to prevent fowling and infection are also disclosed.

A barrier system is provided for use in reducing infections associated with post-operative surgical incision and/or a percutaneous medical device, such as a catheter, that is disposed within the surgical incision. Such a barrier system may include: a barrier device having a skin-contacting surface and a catheter-receiving surface; and an adhesive composition configured for adhering to skin, the barrier device, and/or the catheter so as to form a barrier at or adjacent to an incision in the skin where the catheter is percutaneously inserted through the skin. A tensioning anchor and associated system of two or more tensioning anchors is provided for post-operative wound closure. A method for applying and removing the barrier device and tensioning anchors is also provided.