A flexible portal cannula for use in arthroscopic surgery. Distally positioned flaps extend radially outwardly from the outer surface of the cannula and are resiliently foldable to lie against the outer surface of the cannula during insertion into a surgical portal, and resiliently biased to return to the radially outwardly extending position when unconstrained. Slots disposed around the perimeter of the flaps for anchoring and sorting sutures.

A nanofluidic peristaltic pump includes an elongated tubular member having a first end, an opposed second end, and an elastic wall defining a flow channel extending between the first and second ends; and a series of shape memory alloy actuator wires extending across and at least partially around the outer surface of the elastic wall at spaced positions along the length of the tubular member, wherein the actuator wires are configured to reversibly and directly compress the wall, and thereby constrict regions of the flow channel, upon an electrothermally induced phase transition of the shape memory alloy. With the flow channel at the first end of the tubular member in fluid communication with a fluid source, an electric current is delivered to the actuator wires to sequentially activate and deactivate them and cause fluid to flow through the flow channel from the first end toward the second end.

In some examples, a device, which may be used to access vasculature or another hollow anatomical structure of a patient, includes a housing, a cannula mechanically coupled to a housing distal end, and a needle configured to be locked in a deployed configuration in which the needle extends within a cannula lumen and protrudes from the cannula distal end. The needle is configured to slide proximally through the cannula lumen from the deployed configuration into a retracted configuration in which at least a portion of the needle is within a housing lumen. The device further includes at least one needle guide configured to maintain the needle along a path in the housing lumen substantially parallel to the needle guide when the needle moves between the deployed configuration and the retracted configuration.

The present invention relates to subcutaneously implanted graft-port systems, devices and methods for establishing access to the vascular system of a patient requiring multiple blood treatments over an extended period of time. The systems, devices and methods disclosed herein reduce miscannulation, promote intra-session hemostasis, and decrease the incidence of bacteremia and sepsis among other improvements and advantages. The devices include a port with a flattened plateau-like surface for receiving an access tube. The flat surface may include a tactile or visual guide to assist with placement of the access tube into the tapered seat. Optional valve mechanisms reduce the size and form factor of the implantable graft-port device and seals the conduit of the port closed to physiologic pressures until the valve is opened upon percutaneous insertion of the access tube. The access tube does not pass into the conduit. A mismatch fit between the access tube and tapered seat causes a decrease in the cross-sectional sealing area, a reduction in the overall device size, and an increase in blood flow during treatment. Lock solutions to prevent fowling and infection are also disclosed.

A system for accessing a patient's vascular system may have a tube with a wall that defines an exterior surface and lumen with a proximal end and a distal end, and a guidewire that is deployable, by sliding distally, from a retracted position in which the guidewire resides in the lumen, to a deployed position in which the guidewire extends beyond the distal end. The system may further have a retraction mechanism that can be actuated to retract the guidewire from the deployed position to the retracted position, or a protective shield that can be actuated to extend distally from the distal end of the tube to cover the guidewire in the deployed position.

A flexible portal cannula for use in arthroscopic surgery. Distally positioned flaps extend radially outwardly from the outer surface of the cannula and are resiliently foldable to lie against the outer surface of the cannula during insertion into a surgical portal, and resiliently biased to return to the radially outwardly extending position when unconstrained. Slots disposed around the perimeter of the flaps for anchoring and sorting sutures.

A method and apparatus are aimed to improve arteriovenous fistula maturation rate by treating the fistula with a crosslink agent solution (fixative solution). The fixative solution will crosslink proteins and biomolecules, allowing formation of crosslinks that stabilize or stable tissue structure. The method and apparatus will address factors that contribute to arteriovenous fistula maturation failure by stopping the neointimal hyperplasia growth after vascular injury and stabilizing the venous wall to prevent the lumen from narrowing.

A sterile vascular access device for placing a central venous catheter (CVC) on a human subject, said device comprising: a flexible enclosure formed of a flexible, transparent, pathogen impermeable medical grade material, said flexible enclosure having a base portion and a top portion, said base portion and said top portion together defining an internal space of the flexible enclosure, said base portion having an adhesive bottom surface adapted to be reversibly attached to the skin of the subject and a top surface connected to the top portion, and said top portion comprising a tubular portion having a proximal end which is connected to the top surface of the base portion and a distal end which is sealed.

The present invention comprises a deformable, implantable subcutaneous port for anchoring a transcutaneous treatment component. A port body portion having a normal area port footprint is adapted by means of a port orifice for receiving and anchoring the transcutaneous treatment component beneath the point of entry into the physiology of a patient and for routing the transcutaneous treatment component. The port body portion is produced from a deformable material and has structure and/or composition that provides deformability characteristics of the port such that collapsing, folding, stretching, elongating and/or twisting the port body portion into a modified port shape having a reduced-size port profile enables removal of the port body portion from the physiology of a patient through a relatively small transcutaneous opening.

The present disclosure is directed to a reversibly removable self-adjusting, perforating and/or guiding port configured to automatically retract a perforating blade or guiding rod upon entering a body cavity, while providing a substantially hermetic seal across the body cavity's wall.