Percutaneous access apparatus is described that comprises a percutaneous fluid access device having an extracorporeal portion, one or more ports accessible from the extracorporeal portion and a septum for sealing each port. A connector device comprising one or more hollow needles is attachable to the percutaneous fluid access device. The apparatus also includes an attachment mechanism for attaching the connector device to the extracorporeal portion and an actuation mechanism that, after the connector device has been attached to the extracorporeal portion, can be used to drive the one or more hollow needles through the septum to establish fluid communication between the one or more hollow needles and the one or more ports. The apparatus may be used for neurosurgery applications.

A safety device for a drug delivery system includes a first member including a first arm having first and second ends and a length extending therebetween and a second member including a second arm having first and second ends and a length extending therebetween. The second end of the first member defines a first wall region. The first member further includes a first guard positioned at or near the second end thereof. The second member is rotatably coupled with the first member, and the second end thereof defines a second wall region and a needle guide member. The second member further includes a second guard positioned at or near the second end thereof. Upon rotatably positioning the second end of the first member near or adjacent to the second end of the second member, the first and second wall regions cooperate to define a container connector receptacle and the first and second guards cooperate to define a hand guard.

Percutaneous access apparatus is described that includes a percutaneous fluid access device having an extracorporeal portion, one or more ports accessible from the extracorporeal portion and a septum for sealing each port. A connector device having one or more hollow needles is attachable to the percutaneous fluid access device. The apparatus also includes an attachment mechanism for attaching the connector device to the extracorporeal portion and an actuation mechanism that, after the connector device has been attached to the extracorporeal portion, can be used to drive the one or more hollow needles through the septum to establish fluid communication between the one or more hollow needles and the one or more ports. The apparatus may be used for neurosurgery applications.