A medical device includes a case obtained by mating a liquid-phase-portion case and a gas-phase-portion case to each other, a membrane member as an elastic member with which a liquid-phase portion covered by the liquid-phase-portion case and a gas-phase portion covered by the gas-phase-portion case are separated from each other, fixing parts and at which the liquid-phase-portion case and the gas-phase-portion case that are mated to each other are fixed to each other, holding surfaces and between which a peripheral edge of the membrane member is held, and a sealing part that seals the entirety of the peripheral edge of the membrane member held between the holding surfaces and. The medical device has a releasing part that releases the pressure in an air gap produced between the sealing part and the fixing parts.

A method of manufacturing a medical device. The medical device includes a case obtained by mating a first case portion and a second case portion to each other, the case having a housing space inside; an elastic membrane as an elastic member attached to the case and with which a first housing space covered by the first case portion and a second housing space covered by the second case portion are separated from each other; fixing parts provided at respective peripheries of the first case portion and the second case portion and at which the first case portion and the second case portion that are mated to each other are fixed to each other; holding surfaces provided at the respective peripheries of the first case portion and the second case portion and between which a peripheral edge of the elastic membrane is held; and a sealing part provided at the periphery of the first case portion or the second case portion on an inner side with respect to the fixing parts and that seals an entirety of the peripheral edge of the elastic membrane held between the holding surfaces. When fixing at the fixing parts and sealing by the sealing part are performed to assemble the first case portion and the second case portion together, an air gap produced between the sealing part and the fixing parts is depressurized or heated.

Disclosed are example embodiments of a dialysis machine having a frame, a cartridge cassette, one or more alignment-locking features, and an actuation mechanism. The frame is fixedly coupled to the dialysis machine, and the cassette is slidably coupled to the frame. The cassette can have one or more track structures, with each of the one or more track structures having a rotor and one or more rollers. The one or more alignment-locking features extend from the frame and are configured to be inserted into one or more alignment features of a disposable cartridge that functions to secure or release the disposable cartridge. The actuation mechanism is made to slide the cassette with respect to the one or more track structures.

A tube pump having a housing in which a large diameter flexible tube is arranged along a lateral wall formed to have a substantially horseshoe shape, and a roller that moves along the lateral wall of the housing. Between a blockage section which pressures and blocks the large diameter tube and a separation section shaped so as to gradually extend away from the rotation center, the lateral wall is provided with a pressure release section having an arc with a radius larger than the blockage section. While the roller is moving through the pressure release section, a communication opening is formed in the large diameter tube pressured by the roller so as to allow communication between a part positioned on an upstream side and a part positioned on a downstream side of the roller, while a size of the communication opening is maintained to be constant.

A dual lumen coaxial cannula assembly includes a first infusion tube having a first elongate body defining a first lumen therethrough, the first infusion tube having a proximal end, a distal end, and a sidewall extending circumferentially therebetween. A second drainage tube is co-axially aligned with the first infusion tube and has a second elongate body with a second lumen defined by a space between the first infusion tube and the second drainage tube. The second drainage tube has a proximal end, a distal end, and a sidewall extending circumferentially therebetween. A connector is attached to the proximal end of the first infusion tube and the proximal end on the second drainage tube. The cannula assembly further includes a distal tip connected to the distal end of the first elongate body and made of a material having a lower hardness than a hardness of the first elongate body.

There is provided an introducer system for percutaneously delivering a first and a second medical device to a patient. The system may comprise an introducer sheath having a longitudinal axis and a lumen formed therein. The system may also comprise a bifurcated hub coupled to a proximal end of the sheath. The hub may comprise a first arm having a first lumen and a first hemostasis valve for the passage of the first medical device. The hub may also comprise a second arm coupled to the first arm and having a second lumen and a second hemostasis valve for the passage of the second medical device. Further, the hub may comprise a connection port such that the first lumen and the second lumen are in communication with the lumen of the introducer sheath for the passage of at least one of the first and second medical devices through the introducer sheath for delivery to the patient.

The application refers to a medical treatment device a medical treatment system and a method for operating the medical treatment device and medical treatment system for treatment of a patient, comprising a sensor interface for receiving sensor data from a plurality of different external and internal peripheral sensors, a controller for processing the received sensor data in order to calculate control data and for providing the calculated control data for controlling medical treatment-related devices or for controlling a configuration of medical treatment-related apparatuses and an output interface for providing the control data.

The present invention discloses a self-sealing cannula and methods of its use. The self-sealing cannula can be minimally invasively placed into the heart for drawing and/or returning blood with a self-sealing function at the interface of the blood access site. The disclosed cannula can be implemented as a single lumen cannula or a double lumen cannula, which can be used with ventricular assist devices for heart support or pump-oxygenators for ECMO and respiratory support. Through a self-sealing mechanism fixed on the ventricular wall or atrial wall, a cannula body is attached to the self-sealing fixture and blood is drawn into the lumen via an external pump and returned to the circulation system through a separate cannula. In the case of the double lumen cannula embodiment, the blood will be drawn into the drainage lumen of the double lumen cannula and returned through an infusion lumen at the desired location. The present invention achieves minimally invasive insertion without surgical sutures to the heart, and allows for optimal drainage of the blood from the heart. With use of the double lumen cannula, it prevents need for multiple cannulation sites, and greatly reduces the blood recirculation. Removal of the cannula is simplified without need for suturing or insertion of a plugging member.

Methods, devices, and systems establish and facilitate retrograde or reverse flow blood circulation in the region of the carotid artery bifurcation in order to limit or prevent the release of emboli into the cerebral vasculature such as into the internal carotid artery. The methods are particularly useful for interventional procedures, such as stenting and angioplasty, atherectomy performed through a transcarotid approach or transfemoral into the common carotid artery, either using an open surgical technique or using a percutaneous technique, such as a modified Seldinger technique or a micropuncture technique.

A disposable fluid pump is provided with a housing including first and second faces, with a sidewall extending between the first and second faces. The housing defines a chamber, with an inlet and an outlet in fluid communication with the chamber. An impeller is rotatably mounted within the chamber and includes a plurality of flexible vanes. Such a pump may be incorporated into a disposable fluid flow circuit that is adapted to be mounted on a durable hardware for processing a fluid. In such a fluid flow circuit, the fluid pump may be integrated into a cassette of the circuit or, alternatively, the inlet and outlet of the fluid pump may be directly connected to fluid flow conduits of the circuit.