Disclosed are example embodiments of a dialysis machine having a frame, a cartridge cassette, one or more alignment-locking features, and an actuation mechanism. The frame is fixedly coupled to the dialysis machine, and the cassette is slidably coupled to the frame. The cassette can have one or more track structures, with each of the one or more track structures having a rotor and one or more rollers. The one or more alignment-locking features extend from the frame and are configured to be inserted into one or more alignment features of a disposable cartridge that functions to secure or release the disposable cartridge. The actuation mechanism is made to slide the cassette with respect to the one or more track structures.

Disclosed are example embodiments of a dialysis machine having a frame, a cartridge cassette, one or more alignment-locking features, and an actuation mechanism. The frame is fixedly coupled to the dialysis machine, and the cassette is slidably coupled to the frame. The cassette can have one or more track structures, with each of the one or more track structures having a rotor and one or more rollers. The one or more alignment-locking features extend from the frame and are configured to be inserted into one or more alignment features of a disposable cartridge that functions to secure or release the disposable cartridge. The actuation mechanism is made to slide the cassette with respect to the one or more track structures.

Apparatus and methods are described, including apparatus (20) for implanting in a heart of a human subject. The apparatus includes an interatrial anchor (22) shaped to define an opening (26) having a diameter of 4-8 mm, and a bag (24) in fluid communication with the opening of the anchor. The apparatus is shaped to fit within a right atrium of the heart of the subject, and has a capacity of between 4 and 20 cm3. Other applications are also described.

The invention relates to a catheter device (100) comprising a catheter (68) for insertion into a living being and at least one lumen (69, 70, 74, 79) for guiding a fluid flow within a section of the catheter device, and comprising a valve for controlling a fluid flow, in particular through a catheter, having a valve control chamber (12, 12a), into which an inlet opening (1a) of an inlet channel (1) and an outlet opening (2a) of an outlet channel (2) open, and further having a closure element (5, 13, 17) which can be moved in the valve control chamber (12, 12a) in a controlled manner and which, in at least a first position (I), closes the outlet opening (2a), in at least a second position (II) closes the inlet opening (1a), and which, in at least a third position (III), keeps open a connecting channel between the inlet opening (1a) and the outlet opening (2a), a valve train (A, A, B, B, 3, 14, 18) being provided and optionally moving the closure element (5, 13, 17) to at least the first, second or third position, and the at least one lumen (68, 70, 74, 79) being fluidically connected to the inlet channel or the outlet channel.

The disclosure describes a low-capacity plasma exchange device, comprising a chassis assembly, wherein a centrifuge component is arranged on the inner side of the chassis assembly, and a medication pump, an anticoagulant pump, and a blood drawing pump are arranged on one side of the top of the chassis assembly relative to the centrifuge component, and a first air detector component is arranged on one side of both the medication pump and the blood drawing pump; in the disclosure, the low-capacity plasma exchange device first collects a certain amount of plasma from the patient's body, then mixes the treatment medication into the blood cells after the removal of plasma and reinfuses them back into the patient's body, achieving the effect of exchange treatment, significantly improving the treatment effect, and solving the problem of poor treatment effects of oral medication and infusion therapy in the existing technology.

Disclosed are example embodiments of a dialysis machine having a frame, a cartridge cassette, one or more alignment-locking features, and an actuation mechanism. The frame is fixedly coupled to the dialysis machine, and the cassette is slidably coupled to the frame. The cassette can have one or more track structures, with each of the one or more track structures having a rotor and one or more rollers. The one or more alignment-locking features extend from the frame and are configured to be inserted into one or more alignment features of a disposable cartridge that functions to secure or release the disposable cartridge. The actuation mechanism is made to slide the cassette with respect to the one or more track structures.

Disclosed are example embodiments of a dialysis machine having a frame, a cartridge cassette, one or more alignment-locking features, and an actuation mechanism. The frame is fixedly coupled to the dialysis machine, and the cassette is slidably coupled to the frame. The cassette can have one or more track structures, with each of the one or more track structures having a rotor and one or more rollers. The one or more alignment-locking features extend from the frame and are configured to be inserted into one or more alignment features of a disposable cartridge that functions to secure or release the disposable cartridge. The actuation mechanism is made to slide the cassette with respect to the one or more track structures.

A suction device configured to simultaneously draw in fluid and expel fluid. The suction device may comprise a barrel defining a cavity and extending from a first end to a second end. A first fluid inlet may be adjacent the first end of the barrel and a second fluid inlet adjacent the second end of the barrel and a first fluid outlet may be adjacent the first end of the barrel and a second fluid outlet adjacent the second end of the barrel. A plunger may be slideably disposed within the cavity of the barrel with a handle assembly operably coupled thereto. A actuation of the handle assembly may be configured to move the plunger within the cavity between the first end and the second end of the barrel.

A suction device configured to simultaneously draw in fluid and expel fluid. The suction device may comprise a barrel defining a cavity and extending from a first end to a second end. A first fluid inlet may be adjacent the first end of the barrel and a second fluid inlet adjacent the second end of the barrel and a first fluid outlet may be adjacent the first end of the barrel and a second fluid outlet adjacent the second end of the barrel. A plunger may be slideably disposed within the cavity of the barrel with a handle assembly operably coupled thereto. A actuation of the handle assembly may be configured to move the plunger within the cavity between the first end and the second end of the barrel.

A ventricular assist device (VAD) for use with a heart includes a housing, an upper membrane pump including a pumping chamber coupled to one-way upper inlet and outlet valves, a lower membrane pump including a pumping chamber coupled to one-way lower inlet and outlet valves, and an actuator that causes the upper membrane pump and the lower membrane pump to alternately draw blood into and pump blood out of their respective pumping chambers, and a control module in operative communication with the actuator, wherein the actuator operates with a pumping frequency which is greater than a pulse frequency of the heart.